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Riboseek is a fast RNA/DNA search. More sensitive than nhmmer at 250x speed. Structure-aware realignment produces MSAs approaching rMSA quality. Plus 1.7M precomputed RNA MSAs, and an API to search your own 📄 www.biorxiv.org/content/10.6... 💾 github.com/steineggerla... 🌐 search.foldseek.com/riboseek

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📣NAR is recruiting a new Executive Editor!📣Seeking an established researcher with expertise in RNA biology and translation mechanisms to help shape the journal's scientific direction, oversee peer review, and support its growth. Apply by 30 Sept 2026: academic.oup.com/nar/pages/ex...

Very sad to learn of the death of Ralf Seidel. He was a superb single molecule biophysicist--especially in studies of nucleic acid/protein complexes. www.physes.uni-leipzig.de/pdi/profil/n...

Nachruf auf Prof. Dr. Ralf SeidelMit tiefer Trauer nehmen wir Abschied von unserem Kollegen Professor Ralf Seidel. Er ist am 17. Juli 2026 plötzlich und völlig unerwartet verstorben. Sein Tod hinterlässt eine große Lücke. Wir vermiss...www.physes.uni-leipzig.de

Congratulations to Professor Xiao Wang of MIT and the the Broad Institute of MIT and Harvard on receiving the 2027 Eli Lilly Award in Biological Chemistry! Dr. Wang's lab creates chemical tools to study tissue function and develops novel RNA therapeutics.

Join us on Aug. 4 for Bianca Chavez's PhD thesis defense! @biancachavez.bsky.social's research in the @cijilim.bsky.social Lab examined how telomere loops help to protect telomeres from degradation. Learn more: ipib.wisc.edu/2026/07/28/i...

IPiB Thesis Defense August 4, 2026: Bianca ChavezChavez’s research in the Lim Lab examined how telomere loops help to protect telomeres from degradation.ipib.wisc.edu

Pls share: U of Washington has an opening for a tenure-track faculty position at the rank of Assistant Professor. This position is expected to specialize in molecular virology or bacteriology. Here is a link: microbiology.washington.edu/index.php/ne...

🧬 Delighted to share our new Nature Communications paper! We show how MCM2-7 double hexamers become active helicases and trigger DNA melting in vivo. Led by Chris Weekes & L. Maximilian Reuter. Congratulations to the whole team! doi.org/10.1038/s414... #DNAReplication

Breaking news: Shanghai Jiao Tong University School of Medicine will launch a “comprehensive investigation” into the previously undisclosed death last year of a 6-year-old girl who had received an experimental gene therapy from one of its scientists. Learn more: https://scim.ag/4yJXPoU

Happy that our most recent paper on nucleotide excision repair mechanisms has now been published in Science Advances. This project was led by @natalia-mg.bsky.social and @callumhaste.bsky.social and focused on visualising early steps of the NER process by #cryoEM. www.science.org/doi/10.1126/...

Visualization of stepwise derepression of TFIIH in global genome nucleotide excision repairCryogenic electron microscopy captures nucleotide excision repair complexes assembling on damaged DNA templates.www.science.org

Thrilled to share our collab led by Grace Hibshman with the Shipman lab! Type IX retron-Kva2 structure reveals phage detection via an HTH fold, not a primary sequence. We computationally designed triggers that program bacteria cell death, pointing toward designer antimicrobials.

www.biorxiv.org/content/10.6...

A superfolding sfPepper enables superresolution and single-molecule RNA imaging in live cellsFluorescent RNAs (FRs) have emerged as powerful tools for the visualization of RNA in live cells. However, the poor folding of FRs is a major limiting factor in many advanced RNA imaging applications....www.biorxiv.org

The LocScale 2.0 and SURFER papers are now both published in final form. LocScale 2.0: www.nature.com/articles/s41... SURFER: onlinelibrary.wiley.com/iucr/doi/10.... Led by @alok-bharadwaj.bsky.social with contributions of former MSc/Bsc students Reinier de Bruin and Lotte Veerbeek.

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Had a blast putting this video abstract together with colleagues for @zjmaggiexu.bsky.social story in @currentbiology.bsky.social on how the "vampire cell" P. collini builds the perfect feeding trap 👀. Be sure to check out the full paper: www.cell.com/current-biol... www.youtube.com/watch?v=Ikzm...

A cellular vampire builds the perfect feeding trap / Curr. Biol., June 24, 2026 (Vol. 36, Issue 14)YouTube video by Cell Presswww.youtube.com

He is a remarkably gifted scientist but he is also a welcome reminder to me that the best ideas in a lab often come from the imagination of trainees. Yiu can read about his integrin work here: www.science.org/doi/10.1126/... and in a preprint we hope to post later this year (watch this space)

Molecular exaptation by the integrin αI domainAn ancient protein domain insertion seamlessly preserved conformational signaling while providing a novel surface for adaptation.www.science.org

Happy to share our latest paper in NAR showing that the 2B sub-domain is a general dimerization domain for the UvrD-family of SF1A helicases including Rep and PcrA, led by Binh Nguyen in collaboration with Eric Galburt's group. doi.org/10.1093/nar/...

Interested in joining our group in Oxford? We are looking for a PDRA with single particle Cryo-EM experience to help us figure out how sphingolipids are transported to the cell surface of Gram-negative bacteria. The deadline is 31st July. Informal enquires are welcome. Please share!

In print today @science.org Laser phase plate improves structure determination of small proteins by cryo-EM | Science www.science.org/doi/10.1126/...

Laser phase plate improves structure determination of small proteins by cryo-EMPhase plates can, in principle, overcome the poor image contrast in cryo–electron microscopy (cryo-EM) and the resulting limits on the structural reconstruction of small proteins. However, previous de...www.science.org

@breakliquid.bsky.social and I are delighted to say our OpenEVO preprint is finally live! An open source hand-made turbidostat that's modular, affordable, and made to be customized. Designed with love for the research community. Enjoy!!!💚 www.biorxiv.org/content/10.6...

OpenEvo: An Open-Source Platform for Automated Evolution and AnalysisHere we introduce OpenEvo, a fully open-source, low-cost turbidostat platform for automated continuous culture and directed evolution experiments. Existing tools are expensive, complex, or lack open-s...www.biorxiv.org

📣 Applications are open for the next NAR Early Career Investigator (ECI) Advisory Board cohort! Work with Executive Editors, help shape journal strategy, and gain insight into peer review during a 2-year term. Apply by 1 Nov 2026: lnkd.in/g233ZCAf #ECR #NAR #AcademicPublishing #MolecularBiology

Beautiful work (and beautiful figures!) from Sashital lab alum @yuktidhingra.bsky.social! Congrats, and looking forward to seeing more exciting RNAP work in the future!