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New paper out today @science.org ! 🐟🧬🧪🦑 #aDNA #genomics #fisheries www.science.org/doi/10.1126/... Bastiaan Star and I discuss applications of marine archaeogenomics for fisheries conservation & restoration in light of recent advances in the field

Beyond the scales: Marine archaeogenomics for the conservation and restoration of fisheriesProtection and restoration of marine environments are essential for food security and climate change mitigation. Yet historical and archaeological research have shown that conservation and management ...www.science.org

This month in our @science.org podcast biography series, Angela Saini talks with Matthew Cobb about what made Francis Crick such a fascinating subject for his book: Crick: A Mind in Motion. Listen here: www.science.org/content/podc... All our biographies so far: www.science.org/content/blog...

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Ebola may have been spreading for months in the DRC before anyone recognized it. A new reconstruction suggests the outbreak was already widespread in the gold-mining town of Mongbwalu by January. It wasn’t officially declared until 15 May. Why did no-one raise the alarm? My story for @science.org 🧪

EXCLUSIVE: Congo’s Ebola epidemic started at least 4 months before it was detectedA remote mining town gripped by fear saw hundreds of suspected cases before the government declared an outbreak, report sayswww.science.org

A liposomal nanoparticle therapeutic takes advantage of temporary blood-brain barrier disruption after surgical resection of #glioblastoma tumors to penetrate margins and deliver drugs such as doxorubicin, according to new preclinical work in #ScienceTranslationalMedicine. https://scim.ag/4vUbUNN

Targeting therapeutic nanoparticles to the glioblastoma resection margin by harnessing postoperative blood-brain barrier disruptionA transient, postoperative window of blood-brain barrier permeability enables repurposing of clinically used liposomal nanoparticles for glioblastoma.scim.ag

Out now in @science.org Atlas of lysosomal aging reveals a metabolite signature shared with lysosomal storage disorders | Science www.science.org/doi/10.1126/...

Atlas of lysosomal aging reveals a metabolite signature shared with lysosomal storage disordersLysosomal dysfunction is a well-recognized feature of aging. Here, we used a suite of tools for rapid lysosomal isolation to construct a multitissue atlas of the metabolite changes lysosomes undergo d...www.science.org

An Editorial in @science.org discusses the recent reorganisation of the UK science ministry, and plans to improve commercialisation of British science. @profgeraintrees.bsky.social & @jameswilsdon.bsky.social argue that capital investment is the main limitation. 🔭🧪⚛️ www.science.org/doi/10.1126/...

Orcas are ramming sunfish so hard they explode. Check out the stunning video at the link. Nice story by @annieroth.bsky.social for @science.org

High-speed orcas are blowing sunfish to smithereensNever-before-seen behavior may represent the giant cetaceans playing with their food, ecologists saywww.science.org

New satellite data reveal in unprecedented detail how groundwater reservoirs permanently lose their ability to store water. https://scim.ag/4h1qteW

A California aquifer may have crossed the point of no returnSatellite data reveal in unprecedented detail how groundwater reservoirs permanently lose their ability to store waterscim.ag

Exclusive: A remote mining town gripped by fear saw hundreds of suspected Ebola cases before the government declared an official outbreak in the Democratic Republic of the Congo, according to a new report. Learn more: https://scim.ag/4fw0Xxd

An analysis of fossil mammals in Science suggests that Mexico served as a long-term evolutionary “holding pen” where North American species adapted and diversified for millions of years before sweeping into South America 2.8 million years ago. https://scim.ag/4fu2QKL

Why is the X chromosome rich in L1 mobile elements? @science.org X-chromosome inactivation draws L1 mutagenesis to the human X chromosome | Science www.science.org/doi/10.1126/...

X-chromosome inactivation draws L1 mutagenesis to the human X chromosomeX-chromosome inactivation (XCI) enables gene dosage compensation in XX eutherians. Long interspersed element-1 (LINE-1 or L1) retrotransposons are unusually abundant on the human X chromosome and are ...www.science.org

"The academic structure … makes planning for a family feel like an impossible luxury." In this Working Life, two postdocs share how, as women in academia, having children can feel impossible—and how talking about it makes them feel less alone. https://scim.ag/46uBWgD #InternationalDayOfFriendship

Our study published today @science.org shows that X-chromosome inactivation (XCI) attracts L1 mutations to the human X chromosome: doi.org/10.1126/scie... With outstanding Perspective from @aurelien-doucet.bsky.social & @retrogenomics.bsky.social: doi.org/10.1126/scie...

Churn, not crisis, for UK science @profgeraintrees.bsky.social & I have written the editorial in this week’s @science.org, reflecting on early moves by the Burnham government + scope for US-UK cooperation on scale-up finance & AI for science www.science.org/doi/10.1126/... @rorinstitute.bsky.social

Research on the fossil record of mammals in Mexico suggests that the geographic region acted as a biodiversity “holding pen” for 10 million years. Learn more this week in Science: https://scim.ag/4xhNmQ9

The move follows a Science and Retraction Watch investigation that revealed the tragedy and raised questions about the paper’s lack of disclosure of safety data and certain funding.

In a new editor’s note added to a paper reporting preclinical studies of a gene-editing treatment that resulted in the death of a Chinese girl, Nature has flagged “concerns” that have emerged about the publication. scim.ag/4vHdfYp

Exclusive: Death of girl in Chinese gene-editing trial was never made publicParents want accountability after study went disastrously wrong, Science and Retraction Watch investigation revealsscim.ag

Activists briefly interrupted the opening ceremony of the 26th annual International AIDS Conference to protest the lack of access in Latin America to lenacapavir, a new long-lasting drug that prevents HIV infection. Learn more: https://scim.ag/4vZ2kJF

In a recent #SciencePodcast🎙️, freelance science journalist Brendan Borrell talks about his work reporting on the previously undisclosed death of a 6-year-old girl in a gene-editing clinical trial in China and the reasons her parents came forward. 🎧 Listen here: https://scim.ag/3RNfStH

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A new U.S. policy that aims to reduce the risks arising from federally funded research with dangerous pathogens is drawing mixed reviews from scientists, with some fearing its vague wording could complicate the rules on what kinds of studies the government will support. https://scim.ag/4bfK3jS

New U.S. rules on risky pathogen research draw mixed reviewsVague language and extensive reviews could impede potentially useful research, some scientists fearscim.ag