Professor, University of Queensland. Retrotransposons and genomics. Views my own. Scholar publications: http://tinyurl.com/3k7r3xvj
If you can't otherwise access it, here's a link to read our recent Science paper for free (valid for the first 2,000 clicks!): www.science.org/eprint/BYBPQ...
X-chromosome inactivation draws L1 mutagenesis to the human X chromosomeX-chromosome inactivation (XCI) enables gene dosage compensation in XX eutherians. Long interspersed element-1 (LINE-1 or L1) retrotransposons are unusually abundant on the human X chromosome and are ...www.science.orgOur study published today @science.org shows that X-chromosome inactivation (XCI) attracts L1 mutations to the human X chromosome: doi.org/10.1126/scie... With outstanding Perspective from @aurelien-doucet.bsky.social & @retrogenomics.bsky.social: doi.org/10.1126/scie...
Interesting preprint from Moran lab showing an alternate L1 endonuclease activity www.biorxiv.org/content/10.6...
www.biorxiv.org