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Riboseek has now a WIP Marv Logo!

Riboseek is a fast RNA/DNA search. More sensitive than nhmmer at 250x speed. Structure-aware realignment produces MSAs approaching rMSA quality. Plus 1.7M precomputed RNA MSAs, and an API to search your own 📄 www.biorxiv.org/content/10.6... 💾 github.com/steineggerla... 🌐 search.foldseek.com/riboseek

Видео

@wheelerlab.org is talking about his effort to build a resource for protein dynamics (PDB for MD). MDRepo is a repository to store simulation data. This is really needed to push the needle in design, function and more. Please help make it successful by sharing your MD data. #ismb2026 🌐 mdrepo.org

My student @yewonhan.bsky.social will talk today at 3DSIG about our work on expanding the AlphaFold database to complexes (31M predictions). It starts at 14.20 in the International Ballroom East. Please join. We also brought Marv stickers with us. #ISMB2026

@rolanddunbrack.bsky.social is talking about kinases and interface scoring (ipSAE). AF’s ipTM score avg. PAE over the full area not just the interface, so disorder and extra domains drag it down. ipSAE uses a PAE cutoff to avoid low scores, therefor only consider good interface contacts. #ismb2026

Christopher E. Mason’s keynote at the HitSeq at #ISMB2026 felt like watching an episode of „Sendung ohne Namen“ (does anybody know it?). A crazy amount of ideas, facts, and sci-fi. From environmental metagenomics to space genomics.

@yewonhan.bsky.social build a website to explore the #ISMB2026 program. Check it out here: yewon-han-bioinfo.github.io/ISMB2026-tal...

Richard Durbin starts the #ISMB2026 with his keynote about BWT for genomic search. A walk-through from BWA to his most recent work on pan-genomes GBWT. www.biorxiv.org/content/10.6.... Congratulations on the accomplishments by a Senior Scientist Award.

I’m at #ISMB2026 in Washington, DC. Please let me know if you’d like to catch up over coffee.

It seems @anthropic.com or OpenAI are unusable for biological work now. I was considering buying a Teams account, but I am worried it will be useless in the end. Has anybody experience with other LLMs?

ICML is happening in Seoul this year, and I’ve been getting several messages about lab visits. Who else will be in town and would like to meet? @milot.bsky.social lab and mine are planning a dinner on July 7th, after the reception. Let me know if you’re interested!

Korea reduces the immigration barriers for foreign researcher www.koreatimes.co.kr/southkorea/2... Happy to see this happening.

Korea expands ‘top-tier' visa to woo global scientists - The Korea TimesKorea is expanding its elite "top-tier" visa program to encompass foreign professors and researchers as part of an aggressive push to secure global...www.koreatimes.co.kr

Folddisco is now published @natbiotech.nature.com. It’s a fast motif search for similar 3D DISCOntinuous residues like catalytic sites or zinc fingers across the entire protein universe. 📄 www.nature.com/articles/s41... 💾 folddisco.foldseek.com​​​​​​​​​​​​​​​​ 🌐 https://search.foldseek.com/folddisco

Structural motif search across the protein universe with Folddisco - Nature BiotechnologyFolddisco enables protein structural motif search in million scale databases.www.nature.com

hetro-di-mers are released now.