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Профиль

Kurianlab

Профиль Vively

RNA biology lab studying cell fate and cell identity in the context of embryonic development and disease @Goethe University #ribosome #translational_control #RBP #splicing #RNA_localizatilzon https://kurianlab.com/ Alum:@salkinstitute @yeo lab, UCSD

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New preprint alert!!! Super proud to finally share an authentic 'tour-de-force' from the amazing PhD students Shivani Gunnan @shivanigunnan.bsky.social, Max Kotz and Lucas Ribas, in collaboration with @friedrich-group.bsky.social 👇a small thread www.biorxiv.org/content/10.6...

Developmental growth rates adapt to enable self-correction of organ morphology after injury.Proportional organ growth requires tissue-level control of cell behavior. Yet the cues that adapt growth rates, especially after organ injury, remain unclear. Here, we uncover that developing organs a...www.biorxiv.org
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Our new study shows a CHD-family remodeler can nucleate and spread H3K9 methylation de novo, inverting the canonical hierarchy between writers and remodelers. www.biorxiv.org/content/10.6...

Nucleosome remodeling by a CHD enzyme promotes H3K9 methylation establishment and spreading via remodeler-writer feedbackIn Schizosaccharomyces pombe , the conserved CHD remodeler Mit1 function within the SHREC remodeler-deacetylase complex (a homolog of the metazoan Mi-2/NuRD complex), which is essential for H3K9 methy...www.biorxiv.org
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Please share! What companies have folks successfully worked with to generate custom antibodies? Rough cost? We've been burned once before and want to try a different company this time around.

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“AlphaFold 3's representational coherence is deeply tied to evolutionary scaffolding, suggesting it functions similarly to an advanced fold-recognition system and highlighting that protein structure prediction from sequence alone is not yet fully solved.”

www.biorxiv.org
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arXiv has spun out as an independent non-profit like openRxiv. Today they announce their new CEO and founding Board blog.arxiv.org/2026/07/30/a...

arXiv welcomes inaugural CEO and founding Board of DirectorsarXiv welcomes inaugural CEO and founding Board of Directorsblog.arxiv.org
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Wow 🤩 @benoitbruneau.bsky.social Very proud! Big congrats!

Gladstone Institutes

Benoit Bruneau will receive the American Heart Association's highest scientific honor in November. @americanheart.bsky.social @benoitbruneau.bsky.social

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This epic paper, which has been a heroic 10 year journey for the lead author, Ricardo Barrientos, is finally out in Cell today! Many thanks to all co-authors, especially Billie Meadowcroft and Andela Saric for their beautiful MD simulations www.cell.com/cell/fulltex...

Basement membrane turnover controls cell shapeBasement membranes are scaffolds of proteins, like collagen, that give organs shape. During development, basement membranes must adapt to the growing organ. We infer how fast the basement membrane ada...www.cell.com
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Next summer's Epigenetics GRC (I'm co-chairing with Deborah Bouch'is) is shaping up nicely with an all-star lineup of speakers working on a broad range of organisms and systems and everything from molecular mechanisms to new phenomena. Apply and put it on your calendar! www.grc.org/epigenetics-...

2027 Epigenetics Conference GRCThe 2027 Gordon Research Conference on Epigenetics will be held in Holderness, New Hampshire. Apply today to reserve your spot.www.grc.org
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A new article from Jeff Coller's lab. www.cell.com/molecular-ce...

Nascent chain folding status modulates ribosome dynamics and mRNA stability through the ribosome-associated chaperone Zuo1Chang et al. show that co-translational protein misfolding feeds back to ribosomes, slowing translation elongation and triggering mRNA decay. The ribosome-associated chaperone Zuo1 mediates this respo...www.cell.com
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Great wrap-up of #2026SDB - if you are hungry for more #devbio, consider joining us for the upcoming Gordon Research Conference & trainee-led Gordon Research Seminar in Developmental Biology, Jan 17-22 at Il Cioccio! 🧬🐟🐀🧪🌱🧫🦎🪰🪱

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Sometimes the dark alleys are in fact dark alleys that we shouldn't have gone down. But sometimes the dark alleys are really the path to enlightenment. And we don't really know, ahead of time, which one is going to go, unfortunately. –@harmitmalik.bsky.social on the Night Science Podcast, episode 6

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Wrote a short piece on Transposable Elements as catalysts of evolutionary innovation for a forthcoming special issue of @naturerevgenet.bsky.social on, duh, Evolutionary Innovation! www.nature.com/articles/s41...

Transposable elements as catalysts of evolutionary innovation - Nature Reviews GeneticsIn this Comment, Cedric Feschotte highlights evidence from diverse lineages showing that transposable elements are key drivers of evolutionary innovation, repeatedly introducing regulatory and coding ...www.nature.com
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🚨 Want to start your lab in Marseille on a broad neuronal/brain development theme? There's an exciting tenure track opportunity at @inp-marseille.bsky.social and others Marseille institutes! Check more details here: neuro-marseille.org/en/blog/juni... or contact me if you have any question

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Thrilled to share that our ENCODE enhancer–gene mapping paper is now out in Nature! An encyclopedia of human enhancer–gene regulatory interactions: www.nature.com/articles/s41... Thread 👇 1/

An encyclopedia of human enhancer–gene regulatory interactions - NatureAn encyclopedia of more than 92 million enhancer–gene regulatory interactions created as part of the ENCODE4 project provides a valuable resource for future studies of gene regulation and human geneti...www.nature.com
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A DNA break-5mC cycle activates transposable elements in Arabidopsis | PNAS www.pnas.org/doi/abs/10.1...

A DNA break-5mC cycle activates transposable elements in Arabidopsis | PNASPlant genomic and epigenomic integrity are perpetually threatened by exogenous and endogenous DNA damage. However, the interplay between DNA damage...www.pnas.org
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Manuscripts with women as corresponding authors are less frequently sent out for review at Science. The ones reviewed receive less favorable reviews by both male and female reviewers.

Javi Ibarrondo

Editorial and peer review dynamics at elite general science journals | Science Advances www.science.org/doi/10.1126/... 🧪

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Nature News covered our preprint on LLM analysis of Preprint-to-Publication transition 😆👇 Think preprints are unreliable? Analysis of 70,000 studies might change your mind www.nature.com/articles/d41... Kudos to @rrust.bsky.social for leading this project👍 www.biorxiv.org/content/10.6...

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In print today @science.org Laser phase plate improves structure determination of small proteins by cryo-EM | Science www.science.org/doi/10.1126/...

Laser phase plate improves structure determination of small proteins by cryo-EMPhase plates can, in principle, overcome the poor image contrast in cryo–electron microscopy (cryo-EM) and the resulting limits on the structural reconstruction of small proteins. However, previous de...www.science.org
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📣 Applications are open for the next NAR Early Career Investigator (ECI) Advisory Board cohort! Work with Executive Editors, help shape journal strategy, and gain insight into peer review during a 2-year term. Apply by 1 Nov 2026: lnkd.in/g233ZCAf #ECR #NAR #AcademicPublishing #MolecularBiology

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