Gene regulation in health and disease | Professor/Vice-Chair @UCSF Dept. of Biochemistry and Biophysic | via Stanford, UCSF and MIT | https://madhanilab.ucsf.edu
Next summer's Epigenetics GRC (I'm co-chairing with Deborah Bouch'is) is shaping up nicely with an all-star lineup of speakers working on a broad range of organisms and systems and everything from molecular mechanisms to new phenomena. Apply and put it on your calendar! www.grc.org/epigenetics-...
2027 Epigenetics Conference GRCThe 2027 Gordon Research Conference on Epigenetics will be held in Holderness, New Hampshire. Apply today to reserve your spot.www.grc.orgHaving chaired an NIH review panel, I know how much effort is put into peer review by everyone involved. This piece lays out the current attack on this system amd why it’s bad for American scientific leadership. It’s exceptionally well written and worth the read. It’s also a call to action.
Lisa SchiffSuch a detailed, powerful accounting by @27unihted.bsky.social of how this administration is destroying the U.S. research enterprise: 27unihted.substack.com/p/the-quiet-... #science #resist #censorship #PeerReview #NIH #Action
A DNA break-5mC cycle activates transposable elements in Arabidopsis | PNAS www.pnas.org/doi/abs/10.1...
A DNA break-5mC cycle activates transposable elements in Arabidopsis | PNASPlant genomic and epigenomic integrity are perpetually threatened by exogenous and
endogenous DNA damage. However, the interplay between DNA damage...www.pnas.orgBrings back some memories. I wrote the title of our paper “A novel base-pairing interaction between U2 and U6 snRNAs suggests a mechanism for the catalytic activation of the spliceosome.” Ira Herskowitz, who was on my thesis committee said I shouldn’t use “suggests” in a title. We left it in!
MRC Laboratory of Molecular BiologyThe LMB warmly welcomes Reinhard Lührmann to deliver the Max Perutz Lecture at 11am (BST) on Monday 13 July titled ‘Structural insights into the cascade of snRNP remodelling steps leading to the formation of a catalytically activated spliceosome’ Read more here: mrclmb.ac.uk/news-events/... #LMBNews
The caption for the photo says ‘Cole Valley’ which is incorrect. It was taken near Buena Vista park in the Haight. And the story isn’t exactly news. SF is famous for its summer fog.. The City Where You’ll Nearly Always Want a Jacket on the Fourth of July www.nytimes.com/2026/07/04/w...
The City Where You’ll Nearly Always Want a Jacket on the Fourth of Julywww.nytimes.com