Department of Immunology Institute of Nutritional Medicine #unihohenheim #immunosky https://immu.uni-hohenheim.de/en
Timo-Daniel Voss @unihohenheim.bsky.social and co-authors show that C-terminal lysine residues localise NLRP10 at lipid droplets and govern #NLRP10 oligomer formation. link.springer.com/article/10.1... Press releases: www.uni-hohenheim.de/index.php?id... idw-online.de/de/news873496
Our friends at Sheerbroke University identified how NLRC5 helps the immune system to combat cancer. Congratulations to Subburaj Ilangumaran and his team! Check out their new publication academic.oup.com/immunotherap...
NLRC5 expression within tumor cells is critical to activate adaptive and innate antitumor immune responsesAbstractIntroduction. Tumors downregulate NLRC5 expression to reduce MHC-I and evade CD8+ T cell–mediated killing. Introducing full-length NLRC5 (N5FL) oracademic.oup.comNLRP10 is activated at lipid droplets. Check out our new paper just published at EMBOReports! link.springer.com/article/10.1...
C-terminal lysine residues localise NLRP10 at lipid droplets and govern NLRP10 oligomer formation - EMBO ReportsNLRP10 is an atypical member of the NLR family because it lacks a leucine-rich repeat domain at its C-terminus. Here, we show that in human epithelial cells and keratinocytes NLRP10 oligomerises in re...link.springer.com
#WeekendRead! #MomIsAlwaysMom! Fan Zheng Chen &co show @science.org that a maternal diet-derived fatty acid contained in breast milk potentiates Th1 responses in newborns protecting against bacteria & viruses throughout adulthood! doi.org/10.1126/scie...
Maternal trans-vaccenic acid shapes neonatal T cell development and early-life immune imprintingHow maternal nutrition influences neonatal immune development and imprinting through breastfeeding remains largely unclear. We report that maternal supplementation with trans-vaccenic acid (TVA), the ...doi.orgZur Wichtigkeit der Freiheit von Wissenschaft. Live in Hohenheim
Universität HohenheimGrundsatzrede von MP Winfried Kretschmann: ➡️ „Die Wissenschaft ist zentral für das Funktionieren einer freien Gesellschaft.“ ➡️ „Um in den Debatten verstanden zu werden, muss Wissenschaft verständlich sein – auch über den akademischen Raum hinaus.“ @regierungbw.bsky.social @mwk-bw.bsky.social
Join us for an all-star line up for the 2026 #KeystoneSymposia on #InnateImmunity, co-organised by @jkagan1.bsky.social & @brozlab.bsky.social A joint meeting with joint meeting with the Keystone Aging Symposium in beautiful Banff, Canada. Register now! #inflammasomes, #TLRs, #myeloid, #epithelia
Our new manuscript describing the function of the basic c-terminal domain of NLRP10 is now available at Biorxiv. www.biorxiv.org/content/10.1...
C-terminal lysine residues localise NLRP10 at lipid compartments and govern NLRP10 oligomer formationNLRP10 is an atypical member of the NOD-like receptor (NLR) family because it lacks a leucine-rich repeat domain at its C-terminus. Recently, NLRP10 has been shown to form an inflammasome, however, th...www.biorxiv.orgVery nice review article on NLRP3 from Alex Weber et al. online! The expanding role of the NLRP3 inflammasome from periodic fevers to therapeutic targets doi.org/10.1038/s415...
The expanding role of the NLRP3 inflammasome from periodic fevers to therapeutic targets - Nature ImmunologyLatz et al. review the molecular mechanisms that drive NLRP3 inflammasome activation and regulation, and discuss emerging targeting strategies.doi.org
Warm invitation to the DGfI Autumn School! 💡 Deadline for application: July 31, 2025 The DGfI Autumn School invites you to embark on an up-to-date educational journey through the immune system. dgfi.org/akademie-fue... Registration: dgfi.org/akademie-fue... Program: dgfi.org/wp-content/u...
Weltweit breitet sich eine neue Coronavariante aus. Der Infektiologe Leif Erik Sander sagt, was inzwischen über die Risiken einer Covid-Erkrankung bekannt ist und wer sich noch mal impfen lassen sollte.
Corona: Neue Variante NB.1.8.1, Impfung, Long Covid - Experte von der Charité klärt aufWeltweit breitet sich eine neue Coronavariante aus. Der Infektiologe Leif Erik Sander sagt, was inzwischen über die Risiken einer Covid-Erkrankung bekannt ist und wer sich noch mal impfen lassen sollte.www.spiegel.de
Our latest work combines human gut epithelial #organoid culture with experimental #Shigella #infections, transposon mutagenesis, and statistical modeling. This has led to the mapping of the comprehensive geneset that drives Shigella epithelial colonization. Out @natgenet.nature.com: rdcu.be/eqGgf
A scalable gut epithelial organoid model reveals the genome-wide colonization landscape of a human-adapted pathogenNature Genetics - A genome-wide screen using human gut epithelial organoids combined with transposon-directed insertion sequencing identifies over 100 Shigella flexneri genes required for...rdcu.be🗣️Our EMBO Lecture Course "Cell-autonomous defense and innate immunity" now is open for registration. We are proud to present an excellent line of speakers! Join us in India! 👇 meetings.embo.org/event/25-imm...
Cell-autonomous defense and innate immunityCell-autonomous defense encompasses the inherent mechanisms of the cell that allow individual cells to protect themselves from infectious and inflammatory dangers. Recent advancements in the field in…meetings.embo.org
Great Promethion-powered research from Anja Bosy-Westphal & colleagues @ Kiel University – “short-term consumption of protein-enriched UPFs did not prevent overeating but did favourably affect energy partitioning”! 🧪 www.nature.com/articles/s42...
Short-term effects of high-protein, lower-carbohydrate ultra-processed foods on human energy balance - Nature MetabolismThis single-blind crossover trial shows that the short-term consumption of protein-enriched ultra-processed foods does not prevent overeating but favourably affects energy partitioning.www.nature.com