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What if you could hear scientific data instead of see it? 🧪 A Science & Society article in EMBO Reports explores how #sonification, the use of sound to represent data, could interpret complex datasets and make #science more accessible: https://link.springer.com/article/10.1038/s44319-024-00230-6

Aflah Hanafiah, Zhonghua Gao et al show that cPRC1.2 complex forms #chromatin loops at poised bivalent promoters. A switch from cPRC1.2-mediated to CTCF-mediated active loops enables differentiation to #neuronal progenitors and activation of lineage-specific genes. link.springer.com/article/10.1...

“… the most impactful publications in modern science are increasingly not primary theoretical or experimental findings, but the methodological innovations that enable and support them.” Read the full Science & Society article by Krauss, Rosenfeld & Bornmann -> link.springer.com/article/10.1...

The second July issue is online: link.springer.com/journal/4431... The cover features work by Naoyuki Inagaki, Kio Yagami and colleagues from NAIST describing spontaneous membrane protrusion and cell morphogenesis via self-propelled #actin filaments. -> link.springer.com/article/10.1...

A new review is online! Monja Müller, Konstanze Winklhofer @ruhr-uni-bochum.de and Fulvio Reggiori discuss the role of E3 #ubiquitin ligases in selective types of #autophagy. -> link.springer.com/article/10.1...

A new review is online! Umut Sahin and Elif Nur Firat-Karalar @cytolabkoc.bsky.social describe the role and alterations of the #centrosome - #cilium - satellite axis in neurodegenerative disease and discuss potential mechanism-based therapeutic strategies. -> link.springer.com/article/10.1...

This knowledge, published in @emboreports.org, has potential in the design and improvement of #immunotherapy treatments. 5/ link.springer.com/article/10.1...

A beautiful image (and study), indeed! A similar image was featured on the Cover of our June issue, Volume 27, issue 12! => link.springer.com/journal/4431...

A Science & Society article reflects on 100 years of the theory of the gene – from its role in explaining inheritance to how it laid the foundation for modern #genetics and continues to evolve with discoveries: https://link.springer.com/article/10.1038/s44319-026-00770-z 🧪 #LifeSciences #research

Francesca Pappacena, Jean-Michel Cioni and co-workers show that lc3b mRNA is translated on #endosomes in #axons and that this local synthesis is vital for clearance of dysfunctional endosomes by #autophagy. #ProteinSynthesis #neurons -> link.springer.com/article/10.1...

Yanis Macé, Nicolas Bidère and co-workers show that CYLD is a target of #caspase -3. CASP3-induced cleavage of CYLD tempers inflammatory signaling and heps maintain #apoptosis silence. #inflammation #CellDeath #ubiquitin -> link.springer.com/article/10.1...

The first July issue is online: link.springer.com/journal/4431... The cover features work by Hsiao-Ying Kuo from NYCU Taipei describing activity-dependent #development of #vocal circuits in the neonatal rodent #forebrain. -> link.springer.com/article/10.1...

Philippe Dehio @pdehio.bsky.social, Christoph Hess and co-authors describe a conserved VPS34-PIKfyve pathway regulating #T cell and amoeboid cell migration speed via #lysosome Ca2+ efflux, #myosin IIA activation and retrograde #actin flow. -> link.springer.com/article/10.1...

Mindong Ren, Michael Schlame and co-authors show that cardiolipin de novo synthesis, but not remodeling, is essential for mouse postnatal maturation of cardiac mitochondria, respiratory chain biogenesis and cardiac function. #lipid #mitochondria -> link.springer.com/article/10.1...

Gayatri Rai, Bama Charan Mondal and co-authors show that the COP9 signalosome and Cullin-RING #ubiquitin ligases regulate the cell fate of myeloid-type blood progenitors in Drosophila via EGF and #WNT #singaling. -> link.springer.com/article/10.1...

Academic independence after the USA's 250th anniversary of the Declaration of Independence? Read why the proposed #OMB policies would undermine research & economic leadership + comment by July13th shorturl.at/2s6f8). At the same time we must get our house in order. link.springer.com/article/10.1...

Timo-Daniel Voss @unihohenheim.bsky.social and co-authors show that C-terminal lysine residues localise NLRP10 at lipid droplets and govern #NLRP10 oligomer formation. link.springer.com/article/10.1... Press releases: www.uni-hohenheim.de/index.php?id... idw-online.de/de/news873496

Schistosomiasis affects 110 million African children. Its control demands an urgent shift from drug treatments to permanent transmission interruption. Read the article by Francisca Mutapi and Mark EJ Woolhouse here: -> link.springer.com/article/10.1...

Margot Sahnine, Dorian Obino and co-workers @pasteur.fr show that N. meningitidis induces membrane protrusions with distinct #F-actin networks in epithelial and endothelial cells. The branched network in endothelia depends on Arf1. #Host-pathogen #membrane -> link.springer.com/article/10.1...

Naoyuki Inagaki at Nara Institute of Science and Technology (NAIST) and co-workers show spontaneous #membrane protrusion and cell morphogenesis happens via self-propelled #actin filaments. link.springer.com/article/10.1... Read the press release here: www.naist.jp/en/research_...