Very cool pair of papers demonstrating little link between amount of additive genetic variation and amount of nucleotide variation within species: journals.plos.org/plosbiology/... www.pnas.org/doi/10.1073/...
Профиль
Jun Ishigohoka
Профиль VivelyEvolutionary biologist. Phenotypic noise < bird migration genomics Tübingen < Plön < Kiel < Sapporo < Tokyo https://junishigohoka.github.io/
New paper out in Phil. Trans. B! We set out to understand how seasonal migration evolves by combining a common garden experiment and scATAC-seq of the hypothalamus in ancestral migratory and derived resident populations of the Eurasian blackcap. 1/n
Genotype-by-environment-by-environment (GxExE) interactions have the potential to shape adaptation in response to multiple stressors https://www.biorxiv.org/content/10.64898/2026.07.21.739626v1
Researchers have discovered a contagious cancer in catfish – just the fourth example of tumour cells that spread naturally from one animal to another go.nature.com/4fsoLR3
Neural correlates of seed-eating in songbirds royalsocietypublishing.org/rspb/article... Our new paper showing that songbirds that dehusk seeds with the beak and tongue have an enlarged trigeminal nucleus in the brainstem, particularly the part where the tongue is represented.
Our latest paper on how transcription factor binding sites for global regulators can evolve in bacteria is now published in eLife! Mutation by mutation, we are uncovering the regulatory landscapes of bacteria. elifesciences.org/digests/1037...
New #microsky#AMR Perspective paper with @penamiller.bsky.social rdcu.be/fqBJo ANTIBIOTIC RESISTANCE (IE MIC) AND TOLERANCE ARE NOT BACTERIAL TRAITS! Please read on if you want an explanation for this provocative claim.
📢 happy to share our new paper in @molecology.bsky.social Common chiffchaff subspecies diverge in the same migration-related region as willow warblers (see thread): onlinelibrary.wiley.com/doi/10.1111/...
#ERGAReads | 🐦⬛ 🦜 🪶 Insights into Convergent Evolution From Studying Amino Acid Patterns in Independent Lineages of Birds academic.oup.com/gbe/article/... #genomes #birds #convergentevolution #birdgenomics @genomebiolevol.bsky.social @erichjarvis.bsky.social
MIT Professor Susumu Tonegawa, renowned molecular biologist and Nobel laureate, dies at 86 news.mit.edu/2026/mit-pro... #neuroscience
I am very happy to share that our article, "Splicing of a core circadian clock gene regulates seasonal adaptations by a winter gating mechanism," is now available in Science Advances. 🎊 (1/4) www.science.org/doi/10.1126/...
New preprint! We sequenced 175 'Alalā (Hawaiian crow) genomes to understand why >50% of eggs fail to hatch in a species recovered from just 9 individuals. What we found was a both exciting and surprising. www.biorxiv.org/content/10.6...
How do aerodynamic constraints and evolutionary pressures shape the diversity of flight in true flies? By integrating wing shape, wing motion and #aerodynamics, this study uncovers similarities as well as striking divergences in flight performance. 🧪 #AcademicSky #evolution plos.io/4b4LMbJ
Immune cells exist as continuous clouds, not discrete categories. In this Perspective, @tal-shay.bsky.social &co reframe immune identity through systems biology, and propose that immunotherapies should aim at dynamics of the cell cloud. 🧪 #AcademicSky #immunology plos.io/4oWuoLG
Seafaring turtles navigate by moving in one direction at a time during ocean migrations, even when doing so causes them to go off course for a while, new research suggests. Learn more in #ScienceAdvances: https://scim.ag/4xNAwtR
From migrants to residents: Genomic insights into adaptive strategies in European robins (Erithacus rubecula) https://www.biorxiv.org/content/10.64898/2026.06.26.734870v1
The lab is at #SMBE2026! Come see @junishigohoka.bsky.social talk on Wednesday in the "Fitness Landscapes" symposium @3:50pm. Jun will talk about our theoretical and experimental efforts to understand the implications of *probabilistic* GP maps for evolution (in contrast w *deterministic* GP maps).
Paper alert!🧬🐦💻 Divergent selection is the textbook explanation for narrow inversion clines. Our blackcap inversion cline doesn't fit: it is wide, and the inversion is always the rarer arrangement. We show that negative frequency-dependent selection shifting between populations underlies this!
A fundamental study of individual variation and contribution of learning to behavioural individuality. Conclusions are supported by compelling, rigorous analysis across a number of experiments in thousands of individuals across genotypes and conditions.
awesome work by @junishigohoka.bsky.social highlighting the underappreciated role of shifting balancing selection. jun used demography inference, pogen simulation under our blackcap demography, and ABC to (i) identify the type of balancing selection and (ii) estimate its spatially varying parameters
Jun IshigohokaPaper alert!🧬🐦💻 Divergent selection is the textbook explanation for narrow inversion clines. Our blackcap inversion cline doesn't fit: it is wide, and the inversion is always the rarer arrangement. We show that negative frequency-dependent selection shifting between populations underlies this!