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Tunable Bessel beam two-photon fluorescence microscopy for high-speed volumetric imaging of brain dynamics

Tunable Bessel beam two-photon fluorescence microscopy for high-speed volumetric imaging of brain dynamicsTunable Bessel beam two-photon fluorescence microscopy enables high-speed volumetric intravital imaging of subcellular dynamics within living mouse brains with fully tunable spatial resolution and volume...buff.ly

Esr1-dependent signaling and transcriptional maturation in the medial preoptic area of the hypothalamus shape the development of mating behavior during adolescence

Esr1-dependent signaling and transcriptional maturation in the medial preoptic area of the hypothalamus shape the development of mating behavior during adolescenceEsr1 directs adolescent transcriptional maturation of medial preoptic GABAergic neurons, enabling the normal development of mating behavior in male and female mice.buff.ly

Multi-timescale neural adaptation underlying long-term musculoskeletal reorganization

Multi-timescale neural adaptation underlying long-term musculoskeletal reorganizationLong-term motor recovery after musculoskeletal alteration relies on gradually developing novel compensatory movements to overcome the rigid, maladaptive timing of stable muscle synergies.buff.ly

Material damage to multielectrode arrays after electrolytic lesioning is insignificant

Material damage to multielectrode arrays after electrolytic lesioning is insignificantAn analysis of the largest publicly available collection of scanning electron microscopy images of explanted multielectrode arrays reveals that electrolytic lesioning causes no significant additional...buff.ly

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Retraction: Exogenous myristate fuels the growth of symbiotic arbuscular mycorrhizal fungi but disrupts their carbon-phosphorus exchange with host plants

Retraction: Exogenous myristate fuels the growth of symbiotic arbuscular mycorrhizal fungi but disrupts their carbon-phosphorus exchange with host plantsMain textbuff.ly

Enterovirus D68 2A protease causes nuclear pore complex dysfunction and independently contributes to motor neuron toxicity

Enterovirus D68 2A protease causes nuclear pore complex dysfunction and independently contributes to motor neuron toxicityEnterovirus D68, a cause of acute flaccid myelitis, disrupts the composition and function of the nuclear pore complex primarily through its 2A protease, which is also toxic to motor neurons.buff.ly

Enterovirus D68 2A protease causes nuclear pore complex dysfunction and independently contributes to motor neuron toxicity

Enterovirus D68 2A protease causes nuclear pore complex dysfunction and independently contributes to motor neuron toxicityEnterovirus D68, a cause of acute flaccid myelitis, disrupts the composition and function of the nuclear pore complex primarily through its 2A protease, which is also toxic to motor neurons.buff.ly

This Reviewed Preprint provides important insights into the field of genomic and transcriptomic prediction of traits across multiple environments. The rationale and analyses conducted to integrate the two types of ~omics datasets across two environments are solid.

Uncovering genetic mechanisms underlying trait variation in switchgrass using explainable artificial intelligenceAltmetric provides a collated score for online attention across various platforms and media.See more detailsbuff.ly

Developmental oligodendrocytes regulate brain function through the mediation of synchronized spontaneous activity

Developmental oligodendrocytes regulate brain function through the mediation of synchronized spontaneous activityDisrupting oligodendrocytes during a narrow early-life window leaves cerebellar circuits permanently mistimed, but adult re-synchronization restores social and motor behavior.buff.ly

Single-step in vitro reconstitution of the <i>Escherichia coli</i> ribosome mediated by two GTPase factors, EngA and ObgE

Single-step in vitro reconstitution of the Escherichia coli ribosome mediated by two GTPase factors, EngA and ObgEA multi-step ribosome assembly method involving changes in ion concentration and temperature can now be carried out in a single step using the two GTPase factors, EngA and ObgE.buff.ly

Constraints on the G1/S transition pathway may favor selection of multicellularity as a passenger phenotype

Constraints on the G1/S transition pathway may favor selection of multicellularity as a passenger phenotypeA genetic analysis in yeast establishes that multicellularity can arise as a side-effect (passenger phenotype) of a completely independent fitness advantage unrelated to the benefits of group formation...buff.ly

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Constraints on the G1/S transition pathway may favor selection of multicellularity as a passenger phenotype

Constraints on the G1/S transition pathway may favor selection of multicellularity as a passenger phenotypeA genetic analysis in yeast establishes that multicellularity can arise as a side-effect (passenger phenotype) of a completely independent fitness advantage unrelated to the benefits of group formation...buff.ly

Quantifying intracellular mechanosensitive response upon spatially defined mechano-chemical triggering

Deployment of endocytic machinery to periactive zones of nerve terminals is independent of active zone assembly and evoked release

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Deployment of endocytic machinery to periactive zones of nerve terminals is independent of active zone assembly and evoked release

Correction: mTORC1/S6K1 signaling promotes sustained oncogenic translation through modulating CRL3^IBTK-mediated ubiquitination of eIF4A1 in cancer cells

Correction: mTORC1/S6K1 signaling promotes sustained oncogenic translation through modulating CRL3^IBTK-mediated ubiquitination of eIF4A1 in cancer cells