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By GAWD a new amazing (and objectively true) talking point in favor of Medicare for All just dropped

This goes hard

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There was a perfect description for this, in the 90s.

Happy #FluorescenceFriday. Embryonic myeloid cells are curious. They emerge early during development and disperse throughout an embryo. During this journey, they interact with different cell populations. This myeloid cell 🔴 is seemingly probing ectoderm cells 🔵 to the point of warping their nuclei.

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RelB drives integrin-mediated stress tolerance and relapse in high-grade serous ovarian cancer

RelB drives integrin-mediated stress tolerance and relapse in high-grade serous ovarian cancerLujano-Olazaba et al. show that ovarian cancer cells expressing integrin αVβ3 have enhanced tumorigenic capacity and are enriched at relapse, suggesting that αVβ3 specifies stress tolerance. Using in vivo models, they demonstrate that genetic knockdown of NF-κB, a stress response pathway, in combination with αVβ3 inhibition reduced relapse and improved survival.dlvr.it

To put it in perspective. The $16M spent on the Reflecting Pool is enough to fully fund 8 multi-year RO1 grants - the NIH’s flagship, gold-standard grant. That grant gave us statins, pacemakers, and LASIK (& lots more). It’s not just the waste. It’s the lost opportunity that the waste represents.

📢🚨 FAIRyfying Microscopy Data does not need to feel sisyphean. Talk to your local Data Steward or image analyst. They are fountains of knowledge zenodo.org/records/2085.... Also, please see our latest public data set on the Bioimage Archive: www.ebi.ac.uk/biostudies/b... Publication out soon 🎉

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Our latest work linking the Golgi Calcium Pump to actin cytoskeleton defects in Hailey Hailey Disease keratinocytes has been accepted for publication in Am J Physiol-Cell Physiol. 🥳 Big thanks to our team and collaborators at UMich Skin Biol Diseases Res Ctr (UM-SBDRC) for making this happen! 🧪

New paper from the lab is out in Cell Reports: www.sciencedirect.com/science/arti...

Biphasic inflammation control by fibroblasts enables spinal cord regeneration in zebrafishFibrosis and persistent inflammation are interconnected processes that inhibit axon regeneration in the mammalian central nervous system (CNS). Here, …www.sciencedirect.com

Get your calendars, because the new 2027 EMBL Annual Poster has arrived: s.embl.org/2027-poster Whether you'd like to enhance your skills in a practical course or engage with the latest research at one of our conferences, we've got you covered. See you at EMBL in 2027! 🙌 #LifeSciences #EMBL

Ameaka Fatima Nkempu, a Johns Hopkins University researcher in public health, was detained by ICE while boarding a domestic flight. She says she is Cameroonian in a Medium article that she authored. As of Thursday morning, the ICE Online Detainee Locator did not list where she was being held.

The goal now is just to discipline labor and crush any popular anticapitalist movement. They’ve achieved a level of wealth that makes profit and loss pure abstraction, now they’re just focused on social control. Fighting taxes isn’t about wealth, it’s about starving the state of resources

www.science.org/doi/10.1126/...

Reconstitution of actomyosin networks in cell-sized liposomes dissects distinct mechanisms of membrane blebbing and symmetry breakingActin network organization dictates how and where membrane blebs form, revealed through reconstitution and simulations.www.science.org

This epic paper, which has been a heroic 10 year journey for the lead author, Ricardo Barrientos, is finally out in Cell today! Many thanks to all co-authors, especially Billie Meadowcroft and Andela Saric for their beautiful MD simulations www.cell.com/cell/fulltex...

Basement membrane turnover controls cell shapeBasement membranes are scaffolds of proteins, like collagen, that give organs shape. During development, basement membranes must adapt to the growing organ. We infer how fast the basement membrane ada...www.cell.com

A new study maps where dormant cancer cells hide in breast tumours: tucked into neighbourhoods of immune + support cells that may shield them from treatment. Understanding these hideouts could lead to new drug targets🧬 @mrc-lms.bsky.social @imperialmed.bsky.social @ucl.ac.uk

Scientists map dormant cancer cells' hideouts, opening new targets for treatmentResearchers at the MRC Laboratory of Medical Sciences (LMS), Imperial College London and UCL Genetics Institute have created a detailed map of cells within breast tumours and identified distinct neigh...lms.mrc.ac.uk

Cheng, B., Li, M., Lin, M., Guo, H., & Xu, F. (2025). Mechanobiology across timescales. Nature Reviews Physics, 7(11), 621–644. www.nature.com/articles/s42... #EpithelialMechanicsReview

A Very Bad Thing to Do….

Now with #AltText !

#EuroBioImaging's UK Node 🇬🇧 is expanding, from 7 to 13 sites after a successful upgrade application. More technologies, FAIR image analysis support & better geographic coverage ... 👀 check out what the upgraded UK Node has to offer! ⤵️ www.eurobioimaging.eu/news/the-uk-... @bioimaginguk.bsky.social

Today at #IALSJanelia, we're exploring super-resolution. This includes spending time at @aicjanelia.bsky.social's iPALM system, where participant are exploring tubulin networks (purples) and focal adhesions (light blue) at the ~20 nm scale! iPALM data by @anjanja1024.bsky.social