Профиль

Alexei Drummond

Professor of Computational Biology, University of Auckland. Atheist, Rock climber, Trail runner. Co-creator of BEAST1 and BEAST2. Founder of Geneious.

2,2 тыс. подписчиков2,1 тыс. подписок14 постов
Публикации
⟳ Репост от Alexei Drummond

Klawitter & @alexeidrummond.bsky.social introduce novel and efficient methods for estimating the credible level of individual tree topologies using tractable tree distributions, specifically conditional clade distribution (CCD). 🔗 doi.org/10.1093/molbev/msag141 #societyjournal #compbio

Bayesian credible sets for phylogenetic tree topologies with applications to coverage analysis and cross-model comparisonAbstract. Credible intervals and credible sets, such as highest posterior density intervals, form an integral statistical tool in Bayesian phylogenetics, bdoi.org
⟳ Репост от Alexei Drummond

Vaughan & @tanjastadler.bsky.social develop a method to infer multitype population trajectories and apply it to MERS-CoV, revealing transmission patterns between camels and humans. 🔗 doi.org/10.1093/molbev/msaf130 #evobio #molbio #virus

Bayesian Phylodynamic Inference of Multitype Population Trajectories Using Genomic DataAbstract. Phylodynamic methods provide a coherent framework for the inference of population parameters directly from genetic data. They are an important todoi.org

Check out our new method for summarising BEAST trees. The CCD0-MAP tree gives much more accurate results than MCC tree. It returns the tree that maximises the product of sampled clade probabilities regardless of whether that tree was sampled. Highly recommend :) journals.plos.org/ploscompbiol...

Accurate Bayesian phylogenetic point estimation using a tree distribution parameterized by clade probabilitiesAuthor summary Our research introduces novel methods to analyse a set of phylogenetic tree topologies, such as those generated by Bayesian Markov Chain Monte Carlo algorithms. We define a new model fo...journals.plos.org
⟳ Репост от Alexei Drummond

My and Derek Setter's work on gene flow is now published in the latest issue of Genetics. We show that it is possible to detect past gene flow between two populations by summarising the asymmetry in pop-specific external branch lengths. 1/2 tinyurl.com/5ff8ch9e

Genealogical asymmetry under the isolation with migration model and a two-taxon test for gene flowAbstract. Methods for detecting gene flow between populations often rely on asymmetry in the average length of particular genealogical branches, with the Atinyurl.com
⟳ Репост от Alexei Drummond

My slightly more considered take on the Marsden fund changes is now here. This govt is focused on the impacts of funding — I don’t mind that — but they don’t seem to have thought for a second about the impact of the lack of it. On people; on society; on academic freedom.

Funding research for economic return sounds good – but that’s not how science really worksThe Marsden Fund was set up to support pure research. Diverting half of it to fund applied research undermines New Zealand’s potential to generate ideas that underpin commercial success.theconversation.com
⟳ Репост от Alexei Drummond

One of the reasons Bluesky is seeing more engagement: other platforms have adopted the behaviour of de-prioritising external links (like, say, to research papers) due to Ad models. See this: bsky.app/profile/alt... Here links can be freely shared without being drowned out or de-emphasized

@altmetric.com on BlueskyWe’re no experts but this sounds like it might be suboptimal for disseminating research. [contains quote post or other embedded content]bsky.app
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