Get excited :) PhyloSpec is coming! A shared standard + modelling language for phylogenetic models. Write a model once, run it across engines like BEAST X, BEAST 2.8 & RevBayes. Easy and reproducible. Built by @tochsner.bsky.social & collaborators (ETH Zürich, Auckland, LMU). phylospec.com
PhyloSpecA standardized way to describe phylogenetic model components, common assumptions, and best practices in the field of phylogenetics.phylospec.comПрофиль
Alexei Drummond
Professor of Computational Biology, University of Auckland. Atheist, Rock climber, Trail runner. Co-creator of BEAST1 and BEAST2. Founder of Geneious.
2,2 тыс. подписчиков2,1 тыс. подписок14 постов
Публикации
⟳ Репост от Alexei Drummond
Klawitter & @alexeidrummond.bsky.social introduce novel and efficient methods for estimating the credible level of individual tree topologies using tractable tree distributions, specifically conditional clade distribution (CCD). 🔗 doi.org/10.1093/molbev/msag141 #societyjournal #compbio
I encourage independent Wikipedia editors with an interest in phylogenetics to review my Draft of the StarBEAST software page. Obviously I have a conflict of interest as an author on the first two versions of this software. I have stated that clearly in the Talk :) en.wikipedia.org/wiki/Draft:S...
Draft:StarBEAST - Wikipediaen.wikipedia.org⟳ Репост от Alexei Drummond
Vaughan & @tanjastadler.bsky.social develop a method to infer multitype population trajectories and apply it to MERS-CoV, revealing transmission patterns between camels and humans. 🔗 doi.org/10.1093/molbev/msaf130 #evobio #molbio #virus
Check out our new method for summarising BEAST trees. The CCD0-MAP tree gives much more accurate results than MCC tree. It returns the tree that maximises the product of sampled clade probabilities regardless of whether that tree was sampled. Highly recommend :) journals.plos.org/ploscompbiol...
⟳ Репост от Alexei Drummond
Looks like another nice example of convergence helping to identify (not so nice for us) adaptation.
Michelle Willecattle B3.13 genotype H5N1 viruses rapidly accumulated adaptations in polymerase genes = better replication in bovine cells, + other mammalian species including humans and pigs: PB2 M631L, PA K497R and PB2 D740N 👉 www.biorxiv.org/content/10.1...
⟳ Репост от Alexei Drummond
If you've never donated to Wikipedia, now's the time. Elon Musk is attacking it because it's one of the only sources of honest, curated information that he can't control. www.newsweek.com/elon-musk-ta...
⟳ Репост от Alexei Drummond
My and Derek Setter's work on gene flow is now published in the latest issue of Genetics. We show that it is possible to detect past gene flow between two populations by summarising the asymmetry in pop-specific external branch lengths. 1/2 tinyurl.com/5ff8ch9e
⟳ Репост от Alexei Drummond
20%, under $15m, of Marsden funding went to social sciences while just under $60m went to hard sciences. Total govt research funding in year to March 2023 was ~$1.1b (0.29% of GDP). Cutting the humanities out of Marsden is just spite.
Rod Emmersonwww.nzherald.co.nz/nz/rod-emmer... Rod Emmerson’s cartoons: Week of December 2 - 8
⟳ Репост от Alexei Drummond
My slightly more considered take on the Marsden fund changes is now here. This govt is focused on the impacts of funding — I don’t mind that — but they don’t seem to have thought for a second about the impact of the lack of it. On people; on society; on academic freedom.
⟳ Репост от Alexei Drummond
How fast are viruses spreading in the wild? Check out our latest study now published in @plosbiology.bsky.social: doi.org/10.1371/jour.... A study performed with Paul Bastide, Pauline Rocu, Denis Fargette, Olivier Hardy, @msuchard.bsky.social, @stephaneguindon.bsky.social, and Philippe Lemey (1/7)
⟳ Репост от Alexei Drummond
PhD opportunity in computational population genetics at @MPI_EVA_Leipzig: Join our fully funded project to develop IBD-segment tools, connecting high-quality genomes from 500 Black Death victims to modern Europeans. 🌍💻🧬 Please spread the word! 📢🙌 #aDNA #PopGen www.eva.mpg.de/de/karriere/...
⟳ Репост от Alexei Drummond
One of the reasons Bluesky is seeing more engagement: other platforms have adopted the behaviour of de-prioritising external links (like, say, to research papers) due to Ad models. See this: bsky.app/profile/alt... Here links can be freely shared without being drowned out or de-emphasized
@altmetric.com on BlueskyWe’re no experts but this sounds like it might be suboptimal for disseminating research. [contains quote post or other embedded content]bsky.app⟳ Репост от Alexei Drummond
Don't forget to submit your abstract for "Probabilistic Modeling in Genomics 2025". Deadline: January 10th, 2025. meetings.cshl.edu/meetings.asp...