Thanks, Henry!
Профиль
Alex Mackintosh
Population genetics | Uppsala
241 подписчиков223 подписок9 постов
Публикации
New preprint on the effect of ancient admixture / structure on genealogical trees. I introduce a new way of summarising reconstructed genealogies that captures a clear signal of ancient gene flow into the ancestors of modern humans. Feedback welcome!
bioRxiv Evolutionary BiologyThe distribution of integer partitions in human genome-wide genealogies reflects gene flow from a super-archaic lineage https://www.biorxiv.org/content/10.64898/2026.07.14.738421v1
⟳ Репост от Alex Mackintosh
How do coevolutionary interactions begin in nature, and what are the first steps of reciprocal adaptation? Our preprint investigates these questions in a natural experiment: an introduced cricket (T. oceanicus) and its acoustically hunting parasitoid (O. ochracea) in Hawaii. shorturl.at/7llsA 1/n
Ecological genomics of a novel host-parasitoid arms-race in natureNovel antagonistic interactions between species are expected to drive especially rapid coevolution. However, little is known about the genomic basis of such coevolution in nature because novel inter-s...shorturl.at
⟳ Репост от Alex Mackintosh
The first chapter of my PhD thesis is out: doi.org/10.1111/mec.... !!! This comparative study explores the presence and maintenance of a joint contact zone among three important forest tree species (formed during recolonisation after the LGM). Trees, genetics and evolution, just a perfect combo!
When South Meets North: A Joint Contact Zone Coinciding With Environmental Gradients in Three Boreal Tree SpeciesPost-glacial recolonisation of Fennoscandia created secondary contact zones in many species, offering opportunities to study how gene flow and selection contribute to their establishment and maintena....doi.org
⟳ Репост от Alex Mackintosh
PREPRINT ALERT! Determinants of chromosomal rearrangements in holocentric Leptidea butterflies www.biorxiv.org/content/10.6... Massive #chromosome reshuffling in Leptidea #butterflies reveals how satellite DNA, rDNA, and duplications—not #transposons, shape the architecture of #genomeevolution.
www.biorxiv.org
⟳ Репост от Alex Mackintosh
New paper out: “allopatric” Drosophila species aren’t so allopatric after all. We show that most currently allopatric species pairs probably overlapped in the past and exchanged genes at levels similar to sympatric pairs. @evolletters.bsky.social doi.org/10.1093/evle... [1/6]
Genomic analyses in Drosophila do not support the classic allopatric model of speciationAbstract. The allopatric model of speciation has dominated our understanding of speciation biology and biogeography since the Modern Synthesis. It is uncondoi.org
⟳ Репост от Alex Mackintosh
Hit me up if you'd like to apply to a Data-driven postdoc fellowship with me in Sweden. 2 year salary, excellent community. Deadline March 31. I have a project idea on reference bias vs pangenome, but keen on hearing ideas. Please share broadly. www.scilifelab.se/data-driven/...
DDLS Research School Postdoc call 2026Call for Academic and Industrial Postdoctoral Fellowships in Data-Driven Life Science 2026 Generic Description of the DDLS Postdoc Program The SciLifeLab and Wallenberg National Program for Data-Drive...www.scilifelab.se
⟳ Репост от Alex Mackintosh
I'm excited to share that our preprint is now available on bioRxiv! Our study challenges the widespread use of molecular genetic diversity as a predictor adaptive potential, with important implications for how genetic data is used to inform conservation decisions. www.biorxiv.org/content/10.6...
Nucleotide diversity is a poor predictor of short-term adaptive potentialA capacity to adapt is essential for a population to avoid extinction in a changing world and is recognised as a global conservation priority. Adaptation requires additive (heritable) genetic variatio...www.biorxiv.org
⟳ Репост от Alex Mackintosh
We are excited to share our recent work on the surprising robustness of Ancestral Recombination Graph (ARG) inference tools to computational phasing errors, now available on BioRxiv: biorxiv.org/content/10.1.... This work is co-advised by @yundeng.bsky.social and Rasmus Nielsen. 1/7
Robustness of Ancestral Recombination Graph Inference Tools to Phasing ErrorsAncestral Recombination Graphs (ARGs) are fundamental population genetic structures that encode the genealogical history of a sample of haplotypes along the genome. They have recently received substan...biorxiv.org
⟳ Репост от Alex Mackintosh
Very happy to announce that the next POPGROUP meeting will take place in Lille on 7-9 January ! Follow @popgroup2026.bsky.social for all updates. 📢 Please share widely ! 📢
POPGROUP59Exciting news! The next #PopGroup meeting will take place in Lille 🍟, France, 7–9 January 2026 – just 1 hour by train from London, Brussels, and Paris. This year, PopGroup will also host ALPHY, the annual meeting of Evolutionary Genomics. More info: populationgeneticsgroup.org.uk See you there !
⟳ Репост от Alex Mackintosh
🚨New paper out in PNAS🚨 Soil eDNA reflects regionally dominant species rather than local composition of tropical tree communities 🧬🌿🌳🌺🧬 We asked about the spatial scale of biodiversity captured by samples of DNA from tropical soils #Luquillo #eDNA. A short 🧵.... www.pnas.org/doi/10.1073/...
PNASProceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...www.pnas.org