Профиль

Very excited to see the first chapter of my PhD out on bioRxiv! It began as a rotation project and became a pivotal part of my PhD on beetles, adding a complementary macroevolutionary perspective to my second chapter on early-stage speciation in Indonesian herbivorous ladybird beetles.

1/ 🧬 & 🖥️ New tool: kmhelpers — a Python toolkit dedicated to kmindex, automating the building, updating & querying of large-scale k-mer genomic indexes. Turning raw sequencing samples into a fast, size-optimized search engine — without needing to be a Bloom-filter expert. 🧵

If you are interested in collecting specimens for chromosomal genomes and/or generating chromosomal reference genomes from specimens that were not cold-chain preserved, please read on and share this thread.

Very happy to announce a big new paper from the lab, led by grad students @smishra677.bsky.social and Laia Pomar-Pallarès (in collaboration with @roblanfear.bsky.social). We introduce a new way to study introgression, with accompanying software (DAFT) 1/n 🧵 www.biorxiv.org/content/10.6...

New PLOS Biology paper arising from a collaboration between us at the Sanger/U Cambridge and the U York and Sheffield, and many more collaborators across the Americas and Europe. Regulatory changes in the same genes (optix, ivory) led to the same colour patterns in mimetic butterflies and moths.

Happy to announce two-fold news! 1) The SCINKD paper is now published in @molbioevol.bsky.social - doi.org/10.1093/molb... 2) SCINKD [v2.2.4] release has reduced runtimes (about 2x) and the revitalized mode for genomes >5Gb is now live and tested on genomes up to 21Gb! 🐸 github.com/DrPintoThe2n...

Sex chromosome identification and genome curation from a single individual with SCINKDAbstract. In most animal species, the sex-determining pathway is typically initiated by the presence/absence of a primary genetic cue at a critical point ddoi.org

@drpintothe2nd.bsky.social et al. present SCINKD as a framework to identify unannotated sex chromosomes and curate diploid genome assemblies from a single individual. 🔗 doi.org/10.1093/molbev/msag067 #evobio #molbio #compbio

Sex chromosome identification and genome curation from a single individual with SCINKDAbstract. In most animal species, the sex-determining pathway is typically initiated by the presence/absence of a primary genetic cue at a critical point ddoi.org

Did you know that many organisms delete parts of their genome during development? To know more please join us at the Roscoff meeting on "Mechanistic and Evolutionary Basis of Programmed DNA Elimination" Sep21- 25, 2026. Please share!
cjm.sb-roscoff.fr/en/conferenc...

Can you believe that until now there were more genomes sequenced for the woolly mammoth than for living African elephants? Today, we bring you the first genomic, continent-scale analyses of 232 high-quality genomes of both species, the savanna and forest elephant. www.nature.com/articles/s41...

Sequencing all complex life in the UK & Ireland could add up to £3bn to the economy over 30 years, a new report finds. Explore the impact of the Darwin Tree of Life Project ⤵️ https://www.sanger.ac.uk/news_item/unlocking-the-value-of-biodiversity-in-the-uk-and-ireland/

Unlocking the value of biodiversity in the UK and IrelandA new economic report analysing the financial impact of sequencing all complex life in the UK and Ireland has shown a huge return on investment and expected growth in scientific research.www.sanger.ac.uk

Excited to share our latest work in Nature. Applying single-molecule and single-cell DNA sequencing methods, we uncover an extraordinary landscape of somatic mutations in immune checkpoint genes in autoimmune B cells, suggesting that somatic mutations may be key to autoimmunity [1/n] rdcu.be/fdqbr

1/ BRAKER4 hatched! The Earth BioGenome Project is on track to sequence ~1.5M eukaryotic species. Every one needs a structural annotation. No Perl monolith was going to survive that. So we rewrote BRAKER from the ground up. github.com/Gaius-August...

🔬 Recruiting a Postdoc!!!! I’m looking for a motivated postdoc to join my lab and work on characterizing the role of a heterochromatin protein involved in a sex-ratio meiotic drive system in Drosophila. If you know someone who might be interested, please share widely!

Excited for this. Teaching popgen is one of my favourite parts of my job and I've wondered about doing an online version of the class for sometime. Teaming up with @jrossibarra.bsky.social to do this is wonderful.

Join our Tree of Life Programme as a Group Leader in Biodiversity Genomics at the Wellcome Sanger Institute. Lead ambitious, large-scale genomics research to understand life’s diversity on Earth. 🔗 Learn more and apply: sanger.wd103.myworkdayjobs.com/en-US/Wellco... 📅 Closing date: 8 February 2026

The Department of Genetics at the University of Cambridge is seeking a talented Postdoctoral Research Associate to work in the group of Dr Felipe Karam Teixeira (www.gen.cam.ac.uk/research-gro...) ➡️For Further details see the link www.cam.ac.uk/jobs/postdoc...

Open postdoc position at @sangerinstitute.bsky.social Tree of Life to contribute to the Biodiversity Cell Atlas, with a focus on spatial transcriptomics. Apply by January 4 sanger.wd103.myworkdayjobs.com/en-GB/Wellco... Please share with anyone who might be interested!