Профиль

A novel stress response pathway mediates biofilm architecture in Pseudomonas aeruginosa PLOS Pathogens by Ainelen Piazza et al from Jakob Malone @johninnescentre.bsky.social with @friendlymicrobe.bsky.social journals.plos.org/plospathogen...

A novel stress response pathway mediates biofilm architecture in Pseudomonas aeruginosaAuthor summary Biofilm formation by the opportunistic pathogen Pseudomonas aeruginosa represents a major clinical challenge, with biofilms typically associated with chronic infection, increased antibi...journals.plos.org

Hello Bluesky! 👋 We're a research group at Imperial College working at the interface of chemistry, biology & biotechnology. 🔬 #BiosyntheticPathways, #NaturalProducts & #Antibiotics 🧬 #EnzymeStructure, #EnzymeMechanism & #EnzymeEngineering ⚗️ #Biocatalysis & #SustainableSynthesis. News to follow

Looking for a 𝐩𝐨𝐬𝐭𝐝𝐨𝐜 in phage research? A 𝟐𝟒-𝐦𝐨𝐧𝐭𝐡 position is available at 𝐂𝐘 𝐂𝐞𝐫𝐠𝐲 𝐏𝐚𝐫𝐢𝐬 𝐔𝐧𝐢𝐯𝐞𝐫𝐬𝐢𝐭é starting 𝐉𝐚𝐧𝐮𝐚𝐫𝐲 𝟐𝟎𝟐𝟕 to develop genetically engineered therapeutic phages against 𝘚. 𝘢𝘶𝘳𝘦𝘶𝘴 biofilms. 📄Details in the attached announcement—please share! #PhageResearch #Postdoc #ISVM

High-quality phage assembly from metagenomes with PALACE www.nature.com/articles/s41...

High-quality phage assembly from metagenomes with PALACE - Nature BiotechnologyPALACE combines homology features and deep learning to improve phage assembly from metagenomics.www.nature.com

Registration is now open for Synthetic Biology UK 2026. Join the UK synthetic and engineering biology community on 2–3 November in Hampshire to explore the future of biological design and innovation. https://ow.ly/x7KT50ZlVF9 🧪

What are your favorite papers that linked patients, traced outbreaks, or distinguished epidemiological hypotheses on the careful basis of just a few SNVs? Like ~ <20? Bacterial best, viruses OK too

@breakliquid.bsky.social and I are delighted to say our OpenEVO preprint is finally live! An open source hand-made turbidostat that's modular, affordable, and made to be customized. Designed with love for the research community. Enjoy!!!💚 www.biorxiv.org/content/10.6...

OpenEvo: An Open-Source Platform for Automated Evolution and AnalysisHere we introduce OpenEvo, a fully open-source, low-cost turbidostat platform for automated continuous culture and directed evolution experiments. Existing tools are expensive, complex, or lack open-s...www.biorxiv.org

With Eugene Koonin, we wrote a rather comprehensive review on the origin, evolution and organization of the #virosphere. We describe all 10 viral realms and the logic behind them, and so much more. Check it out! comptes-rendus.academie-sciences.fr/biologies/ar...

#microsky New preprint from the lab! Widespread immune systems protect bacteria against conjugative plasmids www.biorxiv.org/content/10.6... Kudos to the extremely talented lead author Ludovic Poiré! Key contributions by @francoisrousset.bsky.social and also help from C. Lesterlin/TacC lab. 🧵⬇️

Widespread immune systems protect bacteria against conjugative plasmidsConjugative plasmids are a class of mobile genetic elements capable of efficient transfer between bacterial cells. Although they can introduce beneficial traits such as antibiotic resistance to recipi...www.biorxiv.org

Are you a UK-based researcher working in microbiology or environmental biotechnology? Researchers at the University of Edinburgh are seeking your views on the natural environment, microbes and microbiomes. Complete their survey by 17 July: https://microb.io/4y7OWoX

New preprint!! 🎉 A cool collaborative work with @copabio.bsky.social and Chase Beisel teams on the phage editing technology. @sarshad.bsky.social led the work from our side to validate & characterize the lib. #phage #phagesky www.biorxiv.org/content/10.6... Work supported by: phagefoundry.org

Targeted DNA nicking enables efficient, single-step and counterselection-free editing of bacteriophage genomesGenetic manipulation of bacteriophages is essential for interrogating phage biology and advancing antimicrobial therapies. However, current genome editing approaches can be inefficient, require multip...www.biorxiv.org

Access Microbiology is recruiting Editor Mentees across all fields of microbiology! Applications close 31 July 2026. For more information and details on how to apply, visit our website: https://microb.io/Vacancies #AcMi

Recruiting a postdoc to join my lab at @lshtm.bsky.social to work in an MRC porgramme grant funded project to dissect the gut colonziation by Klebsiella. In vivo and in vitro models, and new approaches to identify Klebsiella factors involved. jobs.lshtm.ac.uk/vacancy.aspx...

Job Opportunity at LSHTM: Research FellowThe London School of Hygiene & Tropical Medicine (LSHTM) is one of the world’s leading public health universities. Our mission is to improve health and health equity in the UK and worldwide; working i...jobs.lshtm.ac.uk

Time from submission to acceptance: 3 UK Prime Ministers.

📢 Join us at the ISVM General Meeting during #VoM2026 in Prague! 📅 6 July 2026 🕠 17:30–18:30 📍 Prague, Czech Republic We'll discuss: 🔹 ISVM development 🔹 Activities for members 🔹 Future directions and member engagement Programme: www.vom2026.org/program #ISVM #Virology #Microbiology #Phages

New paper in collaboration with @proftracypalmer.bsky.social, @lislowe.bsky.social and many more. We show that mycobacteria produce Type VII secreted anti-bacterial protein toxins. Excited to explore this new area of mycobacterial biology. www.nature.com/articles/s41...

Check out our latest T7SS toxin story. These reverse toxins aren’t as rare as we thought!

Out Now! Phages tame plant pathogens #MicroSky

Phages tame plant pathogensNature Microbiology, Published online: 23 June 2026; doi:10.1038/s41564-026-02395-3Predicting infection heterogeneity requires looking beyond the host. Phage–bacteria coevolution in tomato fields maintains diverse bacterial strategies and explains uneven disease occurrence across plant populations.go.nature.com

Structures of DnaA domain I reveal a dimer conserved across Actinomycetes academic.oup.com/nar/article/...

Structures of DnaA domain I reveal a dimer conserved across ActinomycetesAbstract. DNA replication is a fundamental process in biology, and initiation marks a key regulatory step. In bacteria, DNA replication is initiated by theacademic.oup.com

Bacterial–fungal interactions: connections and consequences Essays Biochem by Rebecca A. Hall and @katherine-baxter.bsky.social portlandpress.com/essaysbioche...