#microsky
Zeynep Baharoglujournals.asm.org/doi/10.1128/... comprehensive review of bacterial RNA modifications 🦠
Профиль
Vivek Mutalik
Профиль VivelyDad, Teacher, Artist, Gardener and Scientist. Change is the only permanent thing in the world. This moment will pass. It has to. Ps. All I post is my personal opinion
🎉final print version in PLOS Genetics @sullivan-lab.bsky.social @biosci.lbl.gov journals.plos.org/plosgenetics...
Cross-family and phage-specific gene requirements for Klebsiella infection revealed by scalable RB-TnSeq genetic screensAuthor summary Bacteriophages, or phages, are viruses that infect bacteria and play central roles in shaping microbial communities across ecosystems. Despite their ecological importance, the bacterial...journals.plos.orgVivek MutalikNew paper 🔔 Collaboration @sullivan-lab.bsky.social Marissa Gittrich led the work Klebsiella phage biology has focused almost entirely on capsulated strains, but capsule loss is the #1 resistance mechanism under phage predation. We used a naturally acapsular host to reveal the receptor landscape
😮🤯
Jeff GrohAvocados come in 2 varieties - A-types start each day female and switch to male midday. B-types do the reverse. In work just published from the last chapter of my PhD, we show this system evolved 40+million yrs ago and is regulated by alleles of 1 transcription factor www.pnas.org/doi/10.1073/...
www.nature.com/articles/s41... #microsky
Eggerthella lenta: metabolism, pathogenesis and therapeutic implications - Nature Reviews MicrobiologyAdvancing microbiome research beyond well-studied bacterial species is key to understanding the full functional diversity and potential of the human gut microbiome. In this Review, Turnbaugh and colle...www.nature.comSorry for this cute looking “incorrect” E. coli! Here is real one 😅 from this cool blast from the past journals.asm.org/doi/pdf/10.1...
Vivek MutalikNew Preprint 🥳 Here we wondered how phages that have been extensively studied in laboratory E. coli strains actually behave when they encounter a real pathogen such as O157:H7 strain...one with a far more complex cell surface & one of the most consequential foodborne pathogens in the United States.
This work is in collaboration with my dear friend 🤗 Ed Dudley who runs 80K+ E. coli collection center foodscience.psu.edu/research/cen...
Strain Collection (Research)foodscience.psu.eduVivek MutalikSurface architecture of the bacterial envelope determines phage adsorption route in pathogenic Escherichia coli O157:H7 www.biorxiv.org/content/10.6...
New Preprint 🥳 Here we wondered how phages that have been extensively studied in laboratory E. coli strains actually behave when they encounter a real pathogen such as O157:H7 strain...one with a far more complex cell surface & one of the most consequential foodborne pathogens in the United States.
Animated E. coli Bacteria DrawingAlt: Animated E. coli Bacteria Drawingstatic.klipy.com
#phagesky #phage
Aude BernheimOut @cp-cellhostmicrobe.bsky.social, natural products meet bacterial immunity! We used genomics to identify lanthivirins: a family of >2,000 lanthipeptide BGCs that protect Actinobacteria against phages. Led by @hshomar.bsky.social & @mariegllm.bsky.social www.sciencedirect.com/science/arti...
www.biorxiv.org/content/10.6... #microsky
Rational design of T-DNA vectors enables predictable, single-copy integration in Arabidopsis thalianaAgrobacterium -mediated transformation is the dominant method for plant transgenesis, yet it frequently produces multi-copy, structurally complex T-DNA insertions associated with transgene silencing, ...www.biorxiv.orgwww.sciencedirect.com/science/arti... #microsky
Bridging cells with devices: emerging reporters and physical interfaces for bacterial biosensorsBacterial biosensors have emerged as versatile platforms for biomedical and environmental applications, yet their real-world deployment is constrained…www.sciencedirect.comwww.biorxiv.org/content/10.6... #microsky
Predicting the protein interaction landscape of a mycobacterial pathogenHigh-dimensional phenotypic screens of bacterial loss-of-function mutant libraries have determined gene-gene connections and specific phenotypes for thousands of bacterial genes in many species, but d...www.biorxiv.orgwww.cell.com/cell-reports... #phage #phagesky
A receptor-centered approach identifies Lom as a LamB-bound superinfection exclusion factor in bacteriophage λGe et al. develop a receptor-centered strategy to identify phage proteins that target
host receptors during infection and discover the λ outer-membrane protein Lom. Lom
binds and occludes LamB, blocki...www.cell.com