Associate Professor @UCLchildhealth studying epithelial, neutrophil and mucosal responses to respiratory virus infections including influenza, RSV and SARS-COV2.
To get better protection against respiratory infections and transmission we need to achieve nasal immunity. A new @cp-immunity.bsky.social review www.cell.com/immunity/abs...
Nasal immunity in respiratory viral infection, transmission, and protectionThe nasal mucosa is a key decision point during respiratory viral infection. Here,
Kazer et al. review new understanding of how local host cell subsets respond during
viral infection and how this know...www.cell.comDelighted to share our new paper, out now in @natureportfolio.nature.com where we show that neutrophil myeloperoxidase (MPO) tracks RSV severity in infants, and can be used as a functional readout of therapeutic efficacy in the lab. 📄 Read it (open access) 👉 rdcu.be/ftx53
Neutrophil myeloperoxidase as a functional biomarker for RSV severity: implications for in vitro therapeutic screeningNature Communications - Preclinical human models are needed to investigate mechanisms and evaluate therapies for severe respiratory syncytial virus (RSV) infection in children. The authors here...rdcu.be
A reminder that measles cannot be treated, it can only be prevented. It is one of the most contagious diseases in the world and can cause blindness, deafness and life-threatening lung and brain infections.
More than 60 children infected in north London measles outbreakCases reported in seven schools and a nursery in Enfield amid concern over low levels of MMR vaccination in capitalwww.theguardian.com
Really excited our paper about how H5N1 rapidly adapted to cattle (and how these adaptations also increased its ability to infect cells from the human respiratory tract) is now published! www.nature.com/articles/s41...
Polymerase mutations underlie early adaptation of H5N1 influenza virus to dairy cattle and other mammals - Nature CommunicationsAvian influenza jumped from wild birds into dairy cattle. Here, the authors report that two mutations in the viral polymerase helped the virus to quickly adapt to cattle. Mutations increased the polym...www.nature.comThinking of pursuing research in Child Health sciences? Join our upcoming online information session where you’ll find out what it’s like to study at a world-leading institution. 🌍 📅 Child Health MRes – 9 February, 17:00-18:00 🔗 Secure your place: www.ucl.ac.uk/population-h...
Graduate Open Events: Paediatric and Child HealthExplore Master’s degrees in Child Health and Paediatric Neuropsychology. Join our virtual open events to meet Programme Directors and plan your next career step.www.ucl.ac.uk
If you'd like to celebrate the biology of viruses - or the fight against viral diseases - this winter, try out our free and updated #VirusSnowflake designs. Please share, and if you have any photos of Virus Snowflakes in your area it would be lovely to see them! cvr-engagement.co.uk/virus-snowfl...
Deadline for abstracts extended to 1st December
Dr Claire SmithInterested in respiratory infections? who isn't! Then register for this fab conference with a fantastic line-up of speakers and sessions @sangerinstitute.bsky.social Abstract submission open until 17th Nov!! @eventswcs.bsky.social coursesandconferences.wellcomeconnectingscience.org/event/air-20...