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Профиль

Eric Topol

Профиль Vively

physician-scientist, author, editor https://www.scripps.edu/faculty/topol/ Ground Truths https://erictopol.substack.com SUPER AGERS https://www.simonandschuster.com/books/Super-Agers/Eric-Topol/9781668067666

Less protein, more lifespan! A comprehensive review of the merits of protein restriction for healthy aging A flip from the proteinmaxxing craze cell.com/cell-press-b...

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Inflammation is a driver of age-related diseases (inflammaging) and this new NYT magazine article gets deep into the progress that is being made to track and block it gift link www.nytimes.com/interactive/...

Inflammation Keeps Us Alive. It's Also Making Us Sick. (Gift Article)The discovery that chronic inflammation is a cause of myriad illnesses could be this century's biggest medical breakthrough.www.nytimes.com
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Killer T cells (CD8+) in Long Covid directed to SARS-CoV-2 and Herpes virus antigens are persistent and may have a causal role www.cell.com/cell-reports...

Persistent cytolytic CD8+ T cells recognize SARS-CoV-2 and herpesvirus epitopes in long COVIDMa et al. perform deep-phenotyping of CD8+ T cells specific for viruses implicated in LC pathogenesis: SARS-CoV-2, CMV, and EBV. These T cells from LC individuals share features of terminal differenti...www.cell.com
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you didn't need AI to predict this..... www.nytimes.com/2026/07/24/w...

Measles Cases Hit New Record in U.S., as Vaccination Rates Wane (Gift Article)The Trump administration has sent mixed messages on vaccinations against measles as cases have continued to climb.www.nytimes.com
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The pro-peptide stacked FDA advisory committee voted to lift the ban for BPC-157, as expected. This ban lifting is baseless and will give the public a sense of legitimacy for a peptide with no clinical trial data to support safety or efficacy. Pathetic.

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Around the world, life expectancy is increasing but the gap vs healthspan is widening. That is, more sickspan. The US has the largest morbidity gap. Let that sink in: The US has the largest morbidity gap. www.thelancet.com/journals/lan...

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"Perhaps the worst blow to food safety science was the administration’s elimination of the National Advisory Committee on Microbiological Criteria for Foods, a group of experts whose recommendations have informed many major food safety programs." gift link www.nytimes.com/2026/07/20/o...

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This is big. The first vaccine tested to PREVENT pancreatic cancer in high-risk individuals aacrjournals.org/cancerdiscov...

First-in-human testing of a mutant KRAS vaccine for pancreatic cancer interception in high-risk cohortsAbstract. Pancreatic ductal adenocarcinoma (PDAC) arises from precursor lesions over a decade-plus, offering a window for interception in high-risk individuals, but current surveillance detects a mino...aacrjournals.org
783,7 тыс.1,1 тыс.

The aortic dissection that led to Senator Graham's sudden death. Could it have been prevented? What is being done to reduce the toll of aortic dissection with so many people having a dilated proximal aorta and so few progressing to a catastrophic event? www.statnews.com/2026/07/15/l...

Graham’s death from aortic dissection raises questions about preventing the rare disorderWhen the body’s most important blood vessel tears from the inside, it’s a medical emergency that can be years in the making.www.statnews.com
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The serious looming further threat to US science www.newyorker.com/magazine/202...

An O.M.B. Plan to Defund Science—and Anything Trump Doesn’t LikeUnder a new proposal, Administration officials could deny government grants to any group or project on the ground that it didn’t fit the President’s agenda.www.newyorker.com
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To get better protection against respiratory infections and transmission we need to achieve nasal immunity. A new @cp-immunity.bsky.social review www.cell.com/immunity/abs...

Nasal immunity in respiratory viral infection, transmission, and protectionThe nasal mucosa is a key decision point during respiratory viral infection. Here, Kazer et al. review new understanding of how local host cell subsets respond during viral infection and how this know...www.cell.com
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It's medicine's clock moment. We don't age linearly or synchronously (our organs and cells). That leads to an inflection point for promoting health and preventing diseases. erictopol.substack.com/p/medicine-i...

Medicine is Moving From Calendars to ClocksProteins Tell How Fast Our Organs and Cells Are Tickingerictopol.substack.com
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GLP-1 drugs helped people with diabetes to prevent pulmonary fibrosis, #LongCovid Work in patients and the mouse model. Open-access journals.asm.org/doi/full/10....

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Long Covid persistent eye symptoms can be debilitating and appear to be related to chronic T-cell mediated neuroinflammation. open-access www.nature.com/articles/s41...

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For treatment and outcomes for cancer, the tumor microenvironment is pivotal, but we've never had a non-invasive way to assess it. Until now, a blood test breakthrough! With sequencing >10 million cells + AI, discovery & validation of a blood test that informs response to therapy and prognosis.

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On our 250th birthday, celebrating the contribution of immigrants and international collaboration —46% of people with doctoral-level degrees working in US science and engineering fields are foreign-born

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On the future of health, towards primary prevention gift link www.wsj.com/health/welln...

The Future of Health—From Head to ToeEarly detection for all sorts of ailments will allow doctors to treat conditions before a lot of damage is done.www.wsj.com
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