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Meet the inaugural winners of the Ctrl Z Award www.science.org/content/arti...

ScienceAdviser Exclusive: Meet the inaugural winners of the Ctrl Z AwardToday in Science and science: Ice age hunters’ penchant for female mammoths, a detailed vagal map, and morewww.science.org

Come be our colleague. I have been in this Division for 27 years (4 as a postdoc and 23 as a PI). It is an amazing place to work, collaborate, and be inspired. If you are applying to be an Assistant or Associate Professor this Fall, don't miss this deadline.

Lab Meeting FAQ kamounlab.dreamhosters.com/KamounLab-Me...

Happy to share the final version of our study on the evolution of chromatin states across eukaryotes, out today in @natgenet.nature.com Led by @crisnava.bsky.social and @seanamontgomery.bsky.social www.nature.com/articles/s41... Some highlights below

Diversity and evolution of chromatin regulatory states across eukaryotes - Nature GeneticsThis study introduces iChIP2, a low-input chromatin immunoprecipitation followed by sequencing method that profiles histone post-translational modifications (hPTMs) simultaneously across diverse eukar...www.nature.com

This study uses phylogenetic modelling to show that #spermconjugation, a type of social cooperation among sperm, has a deep and pervasive evolutionary history, including repeated convergence of both structures and their underlying proteins. www.nature.com/articles/s41...

Pervasive convergent evolution of sperm conjugation across the Arthropoda tree of life - Nature CommunicationsSperm cells evolve rapidly and have unique life histories. This study uses phylogenetic modelling to show that sperm conjugation, a type of social cooperation among sperm, has a deep and pervasive evo...www.nature.com

The headlines are still covering the cyclosporiasis outbreak from lettuce, but let's talk about a different summer, long ago. The headlines in Bavaria would have called it "summer diarrhea" & it was killing babies. Enter our hero, Professor Theodor Escherich of the Julius Hospital, Würzburg.

Our study published today @science.org shows that X-chromosome inactivation (XCI) attracts L1 mutations to the human X chromosome: doi.org/10.1126/scie... With outstanding Perspective from @aurelien-doucet.bsky.social & @retrogenomics.bsky.social: doi.org/10.1126/scie...

Next summer's Epigenetics GRC (I'm co-chairing with Deborah Bouch'is) is shaping up nicely with an all-star lineup of speakers working on a broad range of organisms and systems and everything from molecular mechanisms to new phenomena. Apply and put it on your calendar! www.grc.org/epigenetics-...

wanna read the latest overview of “internal evolutionary conflicts” — scenarios where genes spread despite being organism-deleterious? and wanna learn how to model them? look at our new preprint! we introduce unifying ideas, and try hard to write accessibly. small 🧵 www.biorxiv.org/content/10.6...

It's been incredibly fun to work with @gauravathreya.bsky.social @yagmurerten.bsky.social @arvidagren.bsky.social @tom-is-kean.bsky.social on internal evolutionary conflicts (also called intragenomic/intraorganismal conflict) and how to model them! See below for Gaurav's great explainer on the paper

EEB Mentor Match is now open! But apps due soon (8/17). Mentees: get help applying for grad school or fellowships in ecology & evolution. Mentors: senior grads, post-docs, or faculty in these fields willing to give advice Org by Diversity Cmte of @asn-amnat.bsky.social Pls share! eebmentormatch.com

EEB Mentor MatchVisit the post for more.eebmentormatch.com

⭐Postdoc position available⭐ How do symbionts evolve new beneficial functions? Join the Henry Lab to investigate how horizontal gene transfer drives host–microbe symbioses. 🦠 Apply below Enquiries: l.henry@qmul.ac.uk Please share! #Postdoc #EvolutionaryBiology #Symbiosis henry-lab.co.uk

Our paper on how better amino acid substitution matrices trained on cleaned alignments improve gene tree inference, and on best practice for cleaning MSAs more broadly, is now out academic.oup.com/mbe/advance-.... New options in both IQTree and Muscle5. @phylowheeler.bsky.social

Improved gene tree inference from removing alignment errors both from focal genes and when training substitution modelsAbstract. Multiple Sequence Alignment (MSA) is a key step in phylogenetic analysis and is prone to error. Unfortunately, algorithms that remove likely aligacademic.oup.com

And just like that… @pravrutharaman.bsky.social is ready to leave us to start her lab at @umassboston.bsky.social We mark this occasion by the ‘solemn’ passing of the crown and specter to the next seniormost postdoc @tamanash.bsky.social; may his reign be as short as British PMs.

So much sadness, excitement, anxiety.. all the feels! This was a long journey that started with a pandemic and ended with “whatever this is”. But I am thrilled that the Raman lab will be a thing. More about our lab soon but for now, must move toddler and dog across the country. Send good vibes

In 2018, I had the opportunity as a PhD student to write a review about chemical waves with @ditalialab.bsky.social Looking back, this was such a fun and valuable experience. If you’re curious to know more about how chemical waves regulate signaling in cells and embryos, check out our review! 🌊

📢 #Postdoc job: I am looking for a #bioinformatician to join my lab for investigating #XchromosomeInactivation and #chromatin-mediated #epigenetic mechanisms underlying #sexbias in #MultipleSclerosis. Please RT

Gabriel Spitzer (@kuow.org) visited our lab to learn about our work to use evolutionary principles to supercharge innate immunity to (hopefully) deploy it in the face of viral infections. Gabriel is a masterful storyteller and would recommend listening to his ‘Pocket Science’ series (each ~12 min)

Priscillia Lhoumaud and I were very happy to write a N&V for a monster paper about intriguing DNMT1 biology by @mafdawson.bsky.social and co, just out in @natgenet.nature.com . Check it out here (and the actual paper in the next post) (1/2) www.nature.com/articles/s41...

SUMOylation fine-tunes DNMT1 to silence viral mimicry transcripts - Nature GeneticsDNMT1 binds unmethylated CpG islands at active genes and, upon catalytic inhibition, redistributes to partially methylated, inaccessible regions, triggering viral mimicry via endogenous retroelements ...www.nature.com

Sometimes the dark alleys are in fact dark alleys that we shouldn't have gone down. But sometimes the dark alleys are really the path to enlightenment. And we don't really know, ahead of time, which one is going to go, unfortunately. –@harmitmalik.bsky.social on the Night Science Podcast, episode 6

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