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Профиль

Patrick R. Secor

Профиль Vively

Associate Professor at Montana State University. Studying bacteria and their viruses with a focus on phage-host-microbe interactions. Lab Website: https://secorlab.org Faculty profile: https://www.montana.edu/mbi/directory/2553333/patrick-secor

⟳ Репост от Patrick R. Secor

If you are a postdoc working on any topic related to environmental microbiology and are looking for exposure, the Thermal Biology Institute (tbi.montana.edu) has slots open for virtual talks via zoom this fall. Email me if you are interested! Seminars are most Mondays, 3-4 pm Mountain Time.

Thermal Biology Institute - Default | Montana State UniversityIndex to the Thermal Biology Institute's website.tbi.montana.edu
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Our Pitt Microbiology and Molecular Genetics department in the School of Medicine is recruiting.. Microbiologists! 🧫🦠🔬🧪 Please apply to join our faculty and enjoy these views 👀 while doing great science cfopitt.taleo.net/careersectio...

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Excited to share the latest work by outstanding PhD student @kdc509.bsky.social. This was one of our first forays into experimental evolution and uncovered some cool connections between potassium transport and antimicrobial resistance in S. aureus. Major kudos to Killian!

Evolution of polyamine resistance in Staphylococcus aureus through modulation of potassium transport | mSphereStaphylococcus aureus is a leading cause of infectious disease-related deaths globally. Understanding factors that govern adaptation and survival of S. aureus and other pathogens in the host environme...journals.asm.org
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schaechter.asmblog.org/schaechter/2... #MicroSky

Elio (1928-2025)by The STC Team — Losing a close friend always saddens one deeply, regardless of age. Losing a person who has so immensely influenced our worldview through his guidance and example makes the sadness e...schaechter.asmblog.org
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⟳ Репост от Patrick R. Secor

Sharing this Pitt article about my helping to lead ASM because it shares my hopes for the scientific and societal good we can do. We are all population biologists, whether or not we know it, and this can enrich us. www.medschool.pitt.edu/news/pitt-s-...

Pitt’s Vaughn Cooper to Serve as President-Elect of the American Society for Microbiology | School of Medicine | University of PittsburghBy Kat Procyk Photography by Rayni Shiring/University of Pittsburgh Vaughn Cooper, professor of microbiology and molecular genetics, University of Pittsburgh School of Medicine, began his new role as ...www.medschool.pitt.edu
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⟳ Репост от Patrick R. Secor

Metal ions are universally required for life, and many of the foundational principles of metal homeostasis have emerged from studies of microbial systems. In this review, I provide a introductory overview targeted to those new to the field. #MicroSky #Metals rdcu.be/eycU2

Microbial metal physiology: ions to ecosystemsNature Reviews Microbiology - Metal ions are required for all cells, and their homeostasis relies on ancient mechanisms that facilitate their import, distribution and storage. In this Review,...rdcu.be
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⟳ Репост от Patrick R. Secor

Still open for applications! We are looking for prospective new faculty doing exciting research in virology or any vector borne diseases

Siân Owen

The Wadsworth Center is expanding it's research focus on #virology /vector-borne diseases! www.asmcareerconnections.org/job/research-scientist-5-g-31/78488664/ This is a unicorn assistant prof equivalent position with 12-month hard money salary and no teaching commitments (!) Reposts appreciated 🙏

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⟳ Репост от Patrick R. Secor

Here's our new broad review on the extended mobility of plasmids, about all mechanisms driving and limiting their transfer. From conjugation to conduction, phage-plasmids to hitchers, molecular to evolutionary dynamics, ecology to biotech. The state of affairs. 1/9 academic.oup.com/nar/article/...

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⟳ Репост от Patrick R. Secor

POSTDOC🚨 With the excellent @anshika22.bsky.social moving to UCI 🥲Anna Zemke and I are again recruiting a postdoc on the HOST-PATHOGEN BIOLOGY of TRACHEOBRONCHITIS. This is a microbiome-device-host immunity problem of broad significance. Contact Dr. Zemke (zemkea at upmc dot edu) if interested! 👇🏻

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Share your stories! @asm.org is calling on members to share stories of how Federal policy changes are affecting your work and institutions. ASM will share your stories with lawmakers and staff to demonstrate impacts on specific legislative districts and states: www.votervoice.net/mobile/ASMUS...

Share How These Federal Policy Changes Impact Your WorldThe changes to the federal workforce, policies, and grants implemented by the new administration are extensive and have far-reaching implications for scientists. The ASM Advocacy team is committed to ...www.votervoice.net
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⟳ Репост от Patrick R. Secor

Hello science fam! We have had a last-minute cancellation for our GRC on Ecological and Evolutionary Genomics and are looking for someone who studies EEG in the context of microbes who would be available to come to beautiful Tuscany in July! Message me!

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Sharing the most significant work from my group, led by the @evolvingstem.bsky.social team. Come for the discoveries of how Pseudomonas adapts in biofilms, stay for the story of how they were discovered by thousands of young scientists in grades 9-12. 🧪🧫🧬🧵 www.biorxiv.org/content/10.1...

Student-led experimental evolution reveals novel biofilm regulatory networks underlying adaptations to multiple nichesWe established a research-education partnership known as EvolvingSTEM that provides secondary school students the opportunity to conduct authentic research experiments centered on microbial evolution....www.biorxiv.org
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⟳ Репост от Patrick R. Secor

Exciting news!! Our latest paper is out in Nat. Microbiol. @natmicrobiol.nature.com We show that a sub-lineage of 7th pandemic V. cholerae has acquired mobile genetic elements packed with phage defense systems—rendering it multi-phage resistant 😳 ..... 1/3 www.nature.com/articles/s41...

West African–South American pandemic Vibrio cholerae encodes multiple distinct phage defence systems - Nature MicrobiologyThe West African–South American lineage of Vibrio cholerae contains multiple distinct anti-phage defence systems that provide resistance to various phage families, including vibriophage ICP1, a key pr...www.nature.com
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We’re thrilled to be featured on the May cover of Nature Microbiology... And our Research Briefing is out now—check it out, it’s 🔥! www.nature.com/articles/s41...

‘Phollowing’ phage outbreaks in microbiomes with live fluorescence microscopy - Nature MicrobiologyPhollow is an in vivo tagging approach for marking bacteriophages with fluorescent proteins while new virions are assembled in bacteria, enabling direct observation of phage outbreaks with single-viri...www.nature.comNature Microbiology

"Phollow" the link to our May issue to read about... 💥lysing bacterial pathogens ⛽microbial alkane oxidation 🌱importance of seed-borne bacteria 🙅‍♀️protective antibodies for norovirus 🚰E. coli in urban drinking water ...and more!👇 www.nature.com/nmicrobiol/v...

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I am thrilled to share the first manuscript from the Wiles lab! We present "Phollow", an in vivo phage-tagging approach that enables direct observation of phage outbreaks with single-virion resolution by live imaging. Here some highlights 👇 www.nature.com/articles/s41...

Phollow reveals in situ phage transmission dynamics in the zebrafish gut microbiome at single-virion resolutionNature Microbiology - ‘Phollow’ is a live imaging-based fluorescence tagging approach that can track phage replication and spread in situ with single-virion resolution.www.nature.com
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⟳ Репост от Patrick R. Secor

Spectacular phage meeting October 12-14 in Washington DC. iasusa.org/bacteriophag... Submit Abstracts by 5/14: 1. Oral presentations (posters) selected from Abstracts 2. Simple Abstract submission; registration and payment can be later 3. Scholarships for New Invest/Trainees

Conference on Bacteriophages: Biology, Dynamics, and Therapeutics - IAS-USAPhysical Education: Bridging Clinical Research and Patient Careiasusa.org
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😮

PLOS Biology

The unique #CellEnvelope of #corynebacteria: @tbharat-lab.bsky.social &co map the C. glutamicum cell surface, revealing a patchy S-layer & specific assembly of the PS2 protein, thereby informing our understanding of cell envelopes that contain #MycolicAcids @plosbiology.org 🧪 plos.io/3Y6JNgw

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Hurray, it is finally out! Meet bacteriophage Bxb1 - the subject of my first full-phage cryo-EM study. My structures are beautifully complemented by the Park Lab’s cryo-ET analysis, shedding light on mycobacteriophage structural changes during infection. www.sciencedirect.com/science/arti...

Structure and infection dynamics of mycobacteriophage Bxb1Mycobacteriophage Bxb1 is a well-characterized virus of Mycobacterium smegmatis with double-stranded DNA and a long, flexible tail. Mycobacteriophages…www.sciencedirect.com
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I'm delighted to share a useful FREE web-based app portal of powerful bioinformatics tools for microbial genomes and shotgun microbiome sequences! It's called Micromics and is built by Middle Author Bioinformatics, led by co-founder @ironark.bsky.social omix.midauthorbio.com

Microbial OmicsA suite of bioinformatics tools for microbial genome and metagenome analysis.omix.midauthorbio.com
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TLDR: most P. aeruginosa cells have active, diverse viromes that affect host-pathogen interactions. ➡️ Pf interact with host cells, interfere w/ antibiotics as @prsecor.bsky.social et al have shown. Dynamics can be FAST! If you don't look carefully, you'll miss it! www.biorxiv.org/content/10.1...

Filamentous cheater phages drive bacterial and phage populations to lower fitnessMany bacteria carry phage genome(s) in their chromosome (i.e., prophage), and this intertwines the fitness of the bacterium and the phage. Most Pseudomonas aeruginosa strains carry filamentous phages ...www.biorxiv.org
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