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Профиль

Erwan Gueguen

Профиль Vively

Molecular microbiology assistant-professor at University of Lyon. I tweet only about Science here. I work on Pectobacteriaceae. I don't like bacteria that can't be genetically manipulated. Lab website: https://sites.google.com/view/mtsb

www.science.org/doi/10.1126/

Antibiotics stimulate protein transfer to persister cellsThe exchange of biological matter between bacterial cells drives adaptation and evolution. However, whether bacteria can exchange functional proteins remains unclear. In this work, we found that antib...www.science.org
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🧬 The kick-off meeting of the Erasmus+ Blended Intensive Programme “Microbes in Focus” took place on May 18th, 2026, with all selected students attending. This international programme focuses on modern molecular microbiology, microbial genetics, and the study of microorganisms. 🧵👇

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MSCA Postdoctoral Fellowship 2026 opportunity. Join my team at Lyon 1 University Claude Bernard to study functional genetics of plant pathogens. Full details are available in the attached document. Internal Deadline: June 15, 2026

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I find something amiss with this figure depicting the GAC system network in Pseudomonas aeruginosa published here: journals.asm.org/doi/10.1128/... Should the RsmA binding sites be represented as a double-stranded helix? 🤔 It’s confusing about what this protein actually does. Don't you think ?

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Nous recrutons un Maître ou une Maîtresse de conférences en bactériologie moléculaire pour notre équipe MTSB au laboratoire MAP à Lyon, France. Le poste combine recherche sur l'adaptation des bactéries phytopathogènes et enseignement en génétique microbienne. Notre team : sites.google.com/view/mtsb

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New pub. from the lab ! We discovered that potato tubers exert intense selective pressure during Dickeya solani infection, driving the rapid emergence of mutations in the sRNA ArcZ. These mutations lead to the appearance of "social cheaters" that sweep through the pop. in as few as 30 generations.

bioRxiv Microbiology

Host infection selects for sRNA variants that drive bacterial social cheating https://www.biorxiv.org/content/10.64898/2025.12.19.695336v1

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I am delighted to be taking part in the 8th meeting on RNA regulation in bacteria and archaea, to be held in Strasbourg from September 1-4. This is my first time, and I'm really looking forward to meeting the experts on this topic. microbialrnameeting.com #MicrobialRNAs

Microbes & RNA 2025 – 8th Meeting on Regulating with RNA in Bacteria and Archaeamicrobialrnameeting.com
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🎓 Looking for a postdoc with a background in bacteriology to join my team to study pectinolytic bacteria via a #MSCA fellowship 🇪🇺 (up to 3 yrs in France). 📅 Expression of interest by June 15. The MSCA application deadline is September 10, 2025. 🔗 Info in attached files #Pectobacteriaceae

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www.jbc.org/article/S002...

Throwing a spotlight on genomic dark matter: the power and potential of transposon-insertion sequencingLinking genotype to phenotype is a central goal in biology. In the microbiological field, transposon mutagenesis is a technique that has been widely used since the 1970’s to facilitate this connection...www.jbc.org
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With each passing day, the articles I read about the Trump administration's research policy plunge me into a deeper and deeper state of dismay. 1/3 www.forbes.com/sites/johndr...

The NSF Is Being Dismantled — With Broad Implications For The American EconomyThe economic consequences of cuts to the National Science Foundation and restricting scientific inquiry on this scale could be far-reaching.www.forbes.com
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Our latest publication has just been released. As I am no longer working on this project, I can share the strains with any team wishing to continue it. It was fun but impossible to work on everything. #pseudomonas #putida enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...

High‐Throughput Tn‐Seq Screens Identify Both Known and Novel Pseudomonas putida KT2440 Genes Involved in Metal ToleranceExposure of Pseudomonas putida KT2440 to toxic metals activates genes PP_1663, PP_5002, PP_5337, and the two-component system RoxSR, possibly linked to membrane integrity, FeS cluster maintenance, an...enviromicro-journals.onlinelibrary.wiley.com
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Submission open for the 8th Meeting on Regulating with RNA in Bacteria and Archaea, September 1 – 4, 2025, Strasbourg. microbialrnameeting.com

Microbes & RNA 2025 – 8th Meeting on Regulating with RNA in Bacteria and Archaeamicrobialrnameeting.com
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"My usual advice to anyone thinking about a lab-based career in science is not to do it unless you can’t imagine not doing it. It is frequently all-consuming, you are never finished, and the outcomes are not always what we want. " 1/2

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journals.plos.org/plosbiology/...

Widespread fungal–bacterial competition for magnesium lowers bacterial susceptibility to polymyxin antibioticsInteractions between fungi and bacteria can both suppress and promote bacterial fitness. This study uncovers a widespread form of antagonism, in which fungi like Candida albicans sequester magnesium t...journals.plos.org
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