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A new study from St. Jude and collaborators shows MBNL1, an RNA-binding protein, plays a key role in leukemia caused by changes in the KMT2A gene by sustaining FLT3 expression. These findings highlight new opportunities for targeted therapies. https://bit.ly/4q14mHI

MBNL1 was identified as a potential cancer drug target for a type of childhood leukemiaDiscover how the RNA-binding protein MBNL1 binds single-stranded DNA to promote a difficult-to-treat childhood cancer.www.stjude.org

NEW: A hacker tracked @agreenberg.bsky.social from his apartment to the subway to his desk using a $30 kids' smartwatch, took photos through its camera and listened in on him at work. Tens of millions of the devices run on three backends in China, and they're all broken.

Hackers Stalked Me by Hijacking a Smartwatch for KidsSecurity researchers tracked and eavesdropped on a WIRED reporter using vulnerabilities in a pink plastic smartwatch. It’s just one piece of a deeply insecure supply chain of GPS-enabled gadgets.www.wired.com

We hold the line, we keep the faith, and we keep forging ahead.

Arizona’s kindergarten vaccination coverage for MMR continues to plummet. And measles is just the bellwether. As vaccination rates fall, other vaccine-preventable diseases will also emerge. RFK Jr. is the absolute GOAT when it comes to putting kids in harm’s way.

I’m skeptical.

The Jan 6 cases are gone. My coworkers and held the line. With a snap of a finger, Todd Blanche's DOJ absolved them of everything and now they face nothing. youtube.com/shorts/r82Sa...

🚨BREAKING: The U.S. Department of Justice (DOJ) took its latest blow in a failing voter roll crusade as a federal judge Thursday dismissed its case targeting Washington, D.C. This marks a 0-21 record for the DOJ. www.democracydocket.com/analysis/doj...

DOJ is 0 for 21 as court dismisses D.C. voter roll grabThe U.S. Department of Justice (DOJ) took its latest blow in a failing voter roll crusade as a federal judge Thursday dismissed its case targeting Washington, D.C.www.democracydocket.com

HAYES: “Major corporations are getting BIG FAT TARIFF REFUNDS — after SCOTUS ruled Trump's tariffs illegal. Walmart: $2.4 BILLION Apple: $2.2 BILLION Ford: $1.3 BILLION As consumers who PAID higher prices get NOTHING.” Heads they win, tails we lose. Trump’s America.

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Dozens of gas-burning power plants are being built across the country, solely to power data centers. These plants could emit as much planet-warming pollution as half of all passenger vehicles in the entire country in a single YEAR. We need a data center moratorium — now.

GOOD NEWS EVERYONE WE BROUGHT BLACK LUNG BACK

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More than 20,000 unaccompanied immigrant children Monday lost their legal representation because the Trump administration has not entered into a new agreement to take over their legal services after it let a longstanding contract with a nonprofit expire ohiocapitaljournal.com/2026/08/04/r...

Legal services contract expires, and unaccompanied immigrant children face deportation • Ohio Capital JournalWASHINGTON — More than 20,000 unaccompanied immigrant children Monday lost their legal representation because the Trump administration has not entered into a new agreement to take over their legal…ohiocapitaljournal.com

This couple came legally. They applied for asylum before their visas expired, wanting to do it all by the books. After six months, they applied for work permits to stay afloat, passing background checks. They worked legally and paid taxes while government delay dragged on. Then ICE came for them.

Nobody should ever endure the nightmare Joke went through. Her abusive ex forced 250 tattoos across her body, but she’s reclaiming her life with free laser removal from Spijt van Tattoo. A powerful step toward healing from severe domestic abuse! 🎥AFP/BBC

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ICE has now spent over $2.2 BILLION on purchasing 4 private prisons from CoreCivic, with the company banking half a billion dollars on the most recent sale. Of course, ICE will not actually operate these facilities; CoreCivic keeps the contracts to run these places for the foreseeable future.

This Thursday, SpaceX insiders will be released from their first post-IPO stock lockup and can cash out early. As I've been saying, this has all the hallmarks of a Ponzi scheme.

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WATCH — “Elon Musk poisoned his town… now he’s running for Congress to stop toxic DATA CENTERS.” @moreperfectunion.bsky.social profiles @justinjpearson.bsky.social and the fight against xAI in MEMPHIS, and the polluting (illegal) turbines xAI uses to power them.

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Rogue AI agents from OpenAI and Anthropic have again been caught trying to disrupt servers and software—and leaving instructions for future bad behavior. www.wired.com/story/ok-wel...

OK, Well, There Are Even More AI Agent Hacking IncidentsRogue AI agents from OpenAI and Anthropic have again been caught trying to disrupt servers and software—and leaving instructions for future bad behavior.www.wired.com

Good. Leave them alone. Ban the practice. Pass my OCTOPUS Act.

🤯 Rep. Max Miller's interview with Jake Tapper was one of the most self-destructive things I've ever witnessed on cable news. Here's the whole thing:

🤯 Max Miller's interview with Tapper is an utter trainwreck 🤯YouTube video by Aaron Ruparwww.youtube.com

NEW: The Olympic canoeist pursued by the Trump administration seeks to permanently sink the Reflecting Pool case, saying Jeanine Pirro shouldn't be able to resurface it later:

Olympic canoeist charged by Pirro seeks to permanently sink Reflecting Pool caseAmid Trump’s criticism of the decision to drop the case, attorneys for David “Davey” Hearn said prosecutors shouldn’t be allowed to try to bring new charges.www.nbcnews.com