Профиль

Ben Allen

Mathematical biologist studying evolution. Professor of Mathematics at Emmanuel College, MA. Queer, nonbinary (they/them). For social and ecological justice. Jewish as in Free Palestine. https://www.emmanuel.edu/emmanuel-mathematical-biology-research-embr

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Публикации

Under what conditions can the evolutionary interests of a gene differ from those of their host organism? Very cool conceptual/mathematical synthesis here!

Gaurav Athreya

wanna read the latest overview of “internal evolutionary conflicts” — scenarios where genes spread despite being organism-deleterious? and wanna learn how to model them? look at our new preprint! we introduce unifying ideas, and try hard to write accessibly. small 🧵 www.biorxiv.org/content/10.6...

Update: the relationship between Shannon entropy and time to fixation does indeed scale to any number of alleles. Thorough investigation here: www.mdpi.com/2073-4425/14...

www.mdpi.comBen Allen

That is, suppose the two alleles have initial proportions p and 1-p. Then t_fix = (effective pop size) * H(p) where H(p) = - p ln p - (1-p) ln (1-p) is Shannon entropy of initial distribution. Idk if this holds for n≥3 alleles, but it would be a real shame if it didn't!

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