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Doudna Lab

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News from Jennifer Doudna's lab at UC Berkeley, Innovative Genomics Institute. Tweets from lab members and not Jennifer Doudna unless signed JD. Tweets represent personal views only. doudnalab.org

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Thank you to the Blavatnik Family Foundation and The New York Academy of Sciences for honoring our research uniting human innate immunity and bacterial anti-phage defense at @danafarber.bsky.social @harvardmicro.bsky.social @harvard.edu bit.ly/4pZUDkF blavatnikawards.org/news/items/t...

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then turned that knowledge into a global movement for conservation. Her work made it impossible to separate what we learn from our obligation to protect it. Generations of researchers have tried to follow that example." 2/2

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From IGI Founder Jennifer Doudna: "Jane Goodall showed us what a life in science could look like: rigorous discovery paired with fierce advocacy for what you study. She gave the world six decades of groundbreaking research on chimpanzees and their habitats... 1/2

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Our story describing the Panoptes bacterial immune defense system is now finally peer-reviewed and published today! www.nature.com/articles/s41...

The Panoptes system uses decoy cyclic nucleotides to defend against phage - NatureThe Panoptes antiphage system defends bacteria by detecting phage-encoded counter-defences that sequester cyclic nucleotide signals, triggering membrane disruption and highlighting a broader strategy of sensing immune evasion through second-messenger surveillance.www.nature.com
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Bacteria use a decoy defense molecule to set a trap for viruses @doudna-lab.bsky.social @ucberkeleyofficial.bsky.social @ucirvine.bsky.social @aaronwhiteley.bsky.social @colorado.edu @aesully98.bsky.social www.nature.com/articles/d41... www.nature.com/articles/s41... www.nature.com/articles/s41...

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Today in @nature.com , we highlight how a cousin of CRISPR-Cas10, mCpol, establishes an evolutionary trap in anti-phage immune systems. Check out @erinedoherty.bsky.social and my work from @doudna-lab.bsky.social lab here: www.nature.com/articles/s41...

A miniature CRISPR–Cas10 enzyme confers immunity by inhibitory signalling - NaturePanoptes, an anti-phage defence system against virus-mediated immune suppression, is revealed.www.nature.com
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Out today in @nature.com, a new paper from @doudna-lab.bsky.social lab, co-first authors @erinedoherty.bsky.social + @benadler.bsky.social and collaborators at @ucsandiego.bsky.social unveils a powerful new defense strategy in the arms war between viruses + microbes. Read here: ow.ly/mPQI50X5g68

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In a recent paper, IGI's @jenniferdoudna.bsky.social @doudna-lab.bsky.social and Jill Banfield @banfieldlab.bsky.social collaborate with UCLA's @jacobsenucla.bsky.social to create a new, tiny #CRISPR tool for quicker, easier plant genome editing! Read more in this Q&A with Steve: ow.ly/6Szs50VGElf

Tiny CRISPR Tool Opens the Door to Faster, Simpler Plant Genome EditingTiny CRISPR Tool Opens the Door to Faster, Simpler Plant Genome Editing - Innovative Genomics Institute (IGI)ow.ly
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A new Pediatric Center for CRISPR Cures builds on the recent saved life of Baby KJ, who expeditiously had bespoke in vivo base genome editing @jenniferdoudna.bsky.social @doudna-lab.bsky.social @innovativegenomics.bsky.social @chanzuckerberg.bsky.social erictopol.substack.com/p/new-center...

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“What we’ve done here is uncover the secret sauce that makes typical #Cas9 — the original Nobel molecule — so efficient and precise." – Co-first author Honglue Shi of the @doudna-lab.bsky.social on his recent paper in Molecular Cell Read here: innovativegenomics.org/uncovering-c...

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Thanks to the BBC's The Inquiry program for great conversations with IGI's @jenniferdoudna.bsky.social @doudna-lab.bsky.social and @urnov.bsky.social about Baby KJ, #CRISPR on-demand, and the future of personalized medicine! Listen here: www.bbc.com/audio/play/w... Photo credit: TODAY

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Hello everyone! I am pleased to share information on the first ever Computational Structural Virology Symposium, conducted August 4th on zoom and highlighting work in this emerging field. You can register for this event here: forms.gle/CNiqskMwQEuV.... Please re-post!

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US supercomputer named after Nobel laureate Jennifer Doudna @jenniferdoudna.bsky.social @innovativegenomics.bsky.social to power AI and scientific research apnews.com/article/nvid...

US supercomputer named after Nobel laureate Jennifer Doudna to power AI and scientific researchA new supercomputer named after a winner of the Nobel Prize in chemistry will help power artificial intelligence technology and scientific discoveries from a perch in the hills above the University of...apnews.com
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Elated to share that I was awarded a K08 clinician-scientist research career development award from the National Institutes of Allergy and Infectious Diseases!

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Congrats to Dr. Honglue Shi @honglue.bsky.social on his latest research! The importance of weak, yet specific, interactions 👀 @doudna-lab.bsky.social @cellpress.bsky.social

Doudna Lab

Now online at Molecular Cell! What makes SpyCas9 such an efficient editor? Read more at: www.cell.com/molecular-ce... Congrats @honglue.bsky.social, Noor Al-Sayyad, and @kevinwasko.bsky.social!

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In a new paper, IGI's Jennifer Doudna @doudna-lab.bsky.social and Jill Banfield @banfieldlab.bsky.social collaborate with UCLA's @jacobsenucla.bsky.social to create a new, tiny #CRISPR tool for quicker, easier plant genome editing! Read more: ow.ly/6Szs50VGElf

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Jennifer Doudna @jenniferdoudna.bsky.social @doudna-lab.bsky.social speaks with Cleo Abrams on the history and future of #CRISPR 🧬. Watch here: youtu.be/0OXaanDHENI?...

You Can Fix Your DNA... Starting Now (feat. Nobel Prize Winner)YouTube video by Cleo Abramyoutu.be
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New Heroes portrait of @jenniferdoudna.bsky.social for the @nationalacademies.org. @doudna-lab.bsky.social explorers.com/jennifer-dou...

New Heroes: Jennifer DoudnaDr. Jennifer Doudna stands at the intersection of biology and history, a scientist whose discoveries have irrevocably altered the course of human understanding. Her pioneering work on CRISPR gene edit...explorers.com
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“What we’ve done here is uncover the secret sauce that makes typical #Cas9 — the original Nobel molecule — so efficient and precise." – Co-first author @honglue.bsky.social of the @doudna-lab.bsky.social on his new paper out today in Molecular Cell Read here: shorturl.at/p664D