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Trying something with huitlacoche (such as quesadilla of huitlacoche) is a good and interesting choice. Other good things to try are guacamole as well as "Chile relleno de queso".

I just saw this message! Going to one branch of the "El Cardenal" restaurants is a good choice. They have good salads and omelettes. They also have some dishes made with avocado, huitlacoche (corn fungus which is delicious), Poblano (pepper) and cheese.

Hi, I recommend checking out some of the papers and software we cite in our paper. Best of luck!

Ese meme es mi filosofía moral.

Spending more time here sounds great!

Thanks, Rebekah! Happy that our paths crossed as some of the last postdocs from Monty.

Natural selection can provoke substantial biases in predicting complex traits from ancient genomes using polygenic scores, so it’s crucial to consider its impact when predicting complex traits! 7/7

In addition, our simulations showed that both types of selection can hamper polygenic scores accuracy for traits like height and BMI, despite having complete genotype data and perfect effect size estimates. 6/7

This leads to a reduction in ancient polygenic scores accuracy for the first, and a reduction that depends on the allele effects for the later. 5/7

We found that while stabilizing selection accelerates the loss of high-effect alleles, directional selection leads to the loss of alleles that drive phenotypes away from the optimal value. 4/7

We observed that each type of selection creates a different pattern for the alleles that are lost and conserved through time between ancient and modern individuals. 3/7

Using forward in time simulations, we modeled a single additive trait evolving under neutrality, stabilizing selection and directional selection. We examined how each of these evolutionary dynamics affects ancient polygenic scores accuracy. 2/7

Thread by Valeria Añorve-Garibay reproduced here: We used a simulation-based approach to explore how natural selection acting on complex traits impacts the predictive accuracy of polygenic scores when applied to ancient samples. 1/7

And also happy to see @psyduckresearch and @valenomics from our group giving talks at #SMBE2024

Jesús Abad Guzmán-López will present his poster "The impact of natural selection in synonymous sites on patterns of genetic diversity" in the poster session from July 10th at 13:20-14:50. Joint work with @johriparul.bsky.social

Sebastián Iturbe will present his work "Leveraging the Ancestral Recombination Graph to estimate the STR mutation model" in the poster session from July 9th at 13:20-14:50. Joint work with Rori Rolhfs and her group.

Alan Izarraras-Gomez will present his poster "Inference of the distribution of fitness effects using local genealogies" in the poster session from July 8th at 14:20-15:50. Joint work with Charleston Chiang and Christian D. Huber.

Alessandro López-Hernández will give the talk "A space-time model for jointly inferring gene flow and natural selection" on July 10th at 15:15-15:30 in the "Olas Altas" room.

Valeria Añorve will give the talk "The contribution of Neanderthal introgression to the heritability of human complex traits in Mexico" on July 10th at 15:30-15:45 in the "Boca de Tomates" room. Joint work with Mashaal Sohail and Emilia Huerta-Sánchez.

Jesús Abad Guzmán-López will present his poster "The impact of natural selection in synonymous sites on patterns of genetic diversity" in the poster session from July 10th at 13:20-14:50. Joint work with @Johri_Parul .