Online now: Activation of the auricular vagus nerve reflex suppresses airway inflammation
Activation of the auricular vagus nerve reflex suppresses airway inflammationBioelectronic technologies are being deployed to treat many inflammatory conditions using transcutaneous auricular nerve stimulation. Shibuya et al. employ viral tracing, chemogenetics, and optogenetics to unveil a sensory skin-lung vagal reflex that suppresses allergic airway inflammation. They identify the neuropeptide CGRPβ as a key mediator and provide a rationale for transcutaneous bioelectronic neuromodulation in asthma.dlvr.it