New Online! Mechanisms, regulation and clinical relevance of necroptosis
Mechanisms, regulation and clinical relevance of necroptosisNature Reviews Molecular Cell Biology, Published online: 21 July 2026; doi:10.1038/s41580-026-01002-xNecroptosis, a programmed cell death characterized by the formation of membrane pores and cell lysis, can be triggered by both cell-extrinsic and cell-intrinsic signals. This Review discusses mechanistic insights into necroptosis pathways mediated by receptors and by Z-nucleic acids.dlvr.it