New Results! A biologically grounded simulation can predict how a drug changes brain circuits and even uncover new biomarkers without being trained on the data first. Mechanistic simulation identifies predictive dose-dependent biomarkers of propofol anesthesia doi.org/10.64898/202... #neuroscience
Mechanistic simulation identifies predictive dose-dependent biomarkers of propofol anesthesiaUnderstanding how receptor-level pharmacological modulation reorganizes large-scale brain circuits remains a central challenge in neuropharmacology. We introduce a multiscale mechanistic model with ex...doi.org