An RNA-guided system that recognizes a noncontiguous DNA code? 🤯 Check out the latest work from the Doudna Lab on the discovery of VIPR. Really exciting biology!
Doudna LabWe present VIPR, a phage-encoded RNA-guided system that recognizes DNA with a noncontiguous code unlike CRISPR. Tiny, programmable, possibly ancestral to CRISPR immunity; VIPR is built around a striking RNA-DNA-DNA triplex.