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Gavin Woodruff

Профиль Vively

Development, evolution, worms, gene name etymology. I log interesting papers, questions, and ideas.

A Fluorescent Dauer Marker in Caenorhabditis inopinata Enables Comparative Analysis of Dauer-Inducing Mechanisms www.biorxiv.org/content/10.6...

A Fluorescent Dauer Marker in Caenorhabditis inopinata Enables Comparative Analysis of Dauer-Inducing MechanismsDauer larvae are a dormant developmental stage in nematodes that is induced by a range of environmental cues. The molecular mechanisms that transduce these cues to regulate dauer entry have been well ...www.biorxiv.org
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Caenorhabditis becei recombinant inbred lines (beRILs) reveal the scope of heritable variation within a gonochoristic nematode population www.biorxiv.org/content/10.6...

Caenorhabditis becei recombinant inbred lines (beRILs) reveal the scope of heritable variation within a gonochoristic nematode populationCaenorhabditis nematodes are a powerful model clade for evolutionary genetics. Isogenic lines and panels of recombinant inbred lines (RILs) are among the most essential tools for genetic studies in th...www.biorxiv.org
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Caenorhabditis tropicalis followed a unique evolutionary path to self-fertility doi.org/10.1093/gene...

Caenorhabditis tropicalis followed a unique evolutionary path to self-fertilityAbstract. Caenorhabditis nematodes provide three natural experiments in which a male/female species evolved to produce one with males and self-fertile hermdoi.org
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! "Moreover, transphyletic transplantation experiments show that the blastopore lip of M. leidyi leads to the generation of a secondary body axis in embryos of the cnidarian Nematostella vectensis."

paveltomancak

Big paper from @hejnol.bsky.social lab. Title says it all. Congrats, Stanislav Kremnyov and the team. www.nature.com/articles/s41...

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Comparative transcriptomics reveals an extracellular worm Argonaute as an ancestral regulator of LTR retrotransposons academic.oup.com/gbe/advance-...

Comparative transcriptomics reveals an extracellular worm Argonaute as an ancestral regulator of LTR retrotransposonsAbstract. Safeguarding the genome from non-self elements is essential for development, reproduction, and ageing. One of the major threats to genomic integracademic.oup.com
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😀 Actually, what is a gain-of-function mutation? doi.org/10.1093/gene...

Actually, what is a gain-of-function mutation?Abstract. For more than a century, scientists have worked to characterize, understand, and predict the consequences of mutations. For almost as long, sciendoi.org
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Microbial genetic screen identifies bacterial genes that compromise Caenorhabditis elegans reproductive fitness journals.asm.org/doi/full/10....

Microbial genetic screen identifies bacterial genes that compromise Caenorhabditis elegans reproductive fitness | mSystemsThis study identifies a direct causal link between a specific bacterial gene and host reproductive fitness. Systematic screening of Escherichia coli mutants showed that deleting one gene severely impa...journals.asm.org
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Internalized Evolutionary Inertia on Body Plan Evolution onlinelibrary.wiley.com/doi/10.1111/...

Internalized Evolutionary Inertia on Body Plan EvolutionAnimal development appears to intrinsically bias phenotypic evolution, though the exact mechanism is unclear. This review discusses potential mechanisms by which animal embryogenesis limits phenotypi...onlinelibrary.wiley.com
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Cathepsin B protease mediates high population density-induced mutagenesis to drive genome evolution and competitive growth www.nature.com/articles/s41...

Cathepsin B protease mediates high population density-induced mutagenesis to drive genome evolution and competitive growth - Nature CommunicationsDensity-dependent population regulation is widespread in animals. Here, the authors identify cathepsin B cysteine protease as a crowd-responding factor that induces increased genome mutagenesis, leadi...www.nature.com
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WormTagDB: a systematic survey of endogenously tagged proteins in Caenorhabditis elegans and roadmap toward the tagged proteome academic.oup.com/g3journal/ad...

WormTagDB: a systematic survey of endogenously tagged proteins in Caenorhabditis elegans and roadmap toward the tagged proteomeAbstract. Endogenous protein tagging in Caenorhabditis elegans enables the direct visualization and manipulation of proteins in vivo, providing native readacademic.oup.com
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Differential Phoretic Vector Use Among Sympatric Caenorhabditis Nematodes and an Association With Invasive Nitidulid Beetles in Southwestern Germany onlinelibrary.wiley.com/doi/full/10....

Differential Phoretic Vector Use Among Sympatric Caenorhabditis Nematodes and an Association With Invasive Nitidulid Beetles in Southwestern GermanyWe show evidence for differential host use among the three sympatric Caenorhabditis, and a novel association with nitidulid beetles for C. apta sp. n. This information adds to our understanding of ho...onlinelibrary.wiley.com
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Genetics Society of America

What is the mutation rate in natural vs laboratory populations? What are the typical divergence times among and within species? In #GENETICS, Wei et al. analyzed the evolution of clonal #Celegans genotypes collected and sequenced in Santeuil wood, France.🪱 🔗 buff.ly/1rINY0W

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Kinetochore proteins control microtubule dynamics in postmitotic neurons to regulate the formation of dendritic spines www.pnas.org/doi/full/10....

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Developmental constraints in the repeated evolution of male tail characters in rhabditid and diplogastrid nematodes journals.plos.org/plosone/arti...

Developmental constraints in the repeated evolution of male tail characters in rhabditid and diplogastrid nematodesA longstanding question in evolutionary biology is how change might be restricted or biased due to developmental constraints. To address this question, we investigated three recurrently evolving chara...journals.plos.org
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A Trojan horse pathogen breaking through partner-choice barriers in the insect gut doi.org/10.1073/pnas...

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Chromosome size as a robust predictor of recombination rate: insights from holocentric and monocentric systems academic.oup.com/genetics/art...

Chromosome size as a robust predictor of recombination rate: insights from holocentric and monocentric systemsAbstract. Recombination is a fundamental evolutionary process essential for generating genetic diversity, facilitating adaptation, and driving speciation.academic.oup.com
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Looking at the EvoWorm 2026 abstracts--I'm getting excited about this meeting!!

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