Профиль

@pilhoferlab.bsky.social @savitski-lab.bsky.social @cibiocm.bsky.social Justin Sonnenburg Erica Sonnenburg @soreklab.bsky.social @baerboletta.bsky.social @jorg-vogel-lab.bsky.social Paul Wilmes @karinaxavierlab.bsky.social Maria Zimmermann-Kogadeeva

Organisers @lisamaierlab.bsky.social @kiranrpatil.bsky.social @robdfinn.bsky.social @embl.org @events.embl.org Speakers Ami Bhatt @dbikard.bsky.social Xiang Gao kc-huang.bsky.social @jhcepas.bsky.social @microbegrrl.bsky.social @keyfm.bsky.social @microbiome.bsky.social Elisabeth Lowe ...

Check the conference link: www.embl.org/about/info/c... Abstract deadline 15 Sep 2026 & Registration (on-site) 27 Oct 2026, don’t miss out! #EMBLGutMicrobeFunction

Unlocking the functional diversity of gut microbiomeswww.embl.org

Featuring leading voices in microbiome research, with sessions on multi-omics, genetic tools, ecological context functions, and new model species. Focusing on research that moves from descriptive to molecular understanding and functional discoveries.

Great collaboration inside and outside @embl.org @EMBLHeidelberg with @savitski-lab.bsky.social @zimmermannlab.bsky.social @sarsarela.bsky.social y.social @linairmi.bsky.social Gad Frankel @imperialcollegeldn.bsky.social and others #Microbiome #AntibioticResistance #AMR

Overall, we demonstrate that specific microbiota compositions affect the fitness of resistant strains through carbohydrate competition, offering a path towards microbiota‑based interventions that actively counter‑select antibiotic-resistant strains without disrupting susceptible community members.

Mechanistically, glyR mutations upregulate the glycoporin GlyP, improving growth in glycerol-rich niches but carrying costs elsewhere. These mutations are under conditional positive selection in clinical isolates, showing how microbiota context can shape the evolution of resistance.

We found that E. coli can be a key driver of selection for a high-fitness antibiotic resistant K. pneumoniae strain in complex communities. Higher-order interactions with other community members could enhance or decrease the selective advantage of the resistant mutant.

We introduce a high-throughput method to quantify resistance-associated fitness costs inside complex gut microbiomes. This lets us identify which microbiota are permissive or restrictive for antibiotic-resistant pathogens.

@pilhoferlab.bsky.social @savitski-lab.bsky.social @cibiocm.bsky.social Justin Sonnenburg Erica Sonnenburg @soreklab.bsky.social @baerboletta.bsky.social Paul Wilmes @karinaxavierlab.bsky.social Maria Zimmermann Kogadeeva

Organisers: @lisamaierlab.bsky.social @kiranrpatil.bsky.social @robdfinn.bsky.social @embl.org @events.embl.org Speakers: Ami Bhatt @dbikard.bsky.social Xiang Gao KC Huang @jhcepas.bsky.social @microbegrrl.bsky.social @keyfm.bsky.social @microbiome.bsky.social Elisabeth Lowe

Check the conference link: www.embl.org/about/info/c... Abstract submission & registration open, don’t miss out! #EMBLGutMicrobeFunction

Unlocking the functional diversity of gut microbiomeswww.embl.org

Featuring leading voices in microbiome research, with sessions on multi-omics, genetic tools, ecological context functions, and new model species. Focusing on research that moves from descriptive to molecular understanding and functional discoveries.

Great collaboration inside and outside @embl.org with @kiranrpatil.bsky.social @indraroux.bsky.social @zimmermannlab.bsky.social @zellerlab.bsky.social @EMBLHeidelberg

We systematically compared essential genes, protein domains & non-coding elements, uncovering toxic modalities & functional redundancy as key aspects of species-specific essentiality.