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Open position in our lab for a research engineer. The applicant must hold a PhD in life sciences and have demonstrable experience in molecular biology and biochemistry. For more info: emploi.cnrs.fr/Offres/CDD/U...

Please join the upcoming Jacques Monod Conference on the mechanistic and evolutionary basis of programmed DNA elimination in Roscoff, France. Deadline for abstract submission extended to May 20, 2026. cjm.sb-roscoff.fr/en/conferenc...

Thank you @cnrsbiologie.bsky.social for the highlight on our recent publication!

Thank you @cnrsbiologie.bsky.social for the highlight (in French) of our work www.insb.cnrs.fr/fr/cnrsinfo/...

Une marque épigénétique qui active pour mieux réprimerChez les eucaryotes, la marque épigénétique H3K27me3 est classiquement associée à la répression transcriptionnelle.www.insb.cnrs.fr

The Jacques Monod Conference on the mechanistic and evolutionary basis of programmed DNA elimination is approaching. There are selected talk slots available. Abstract submission deadline: Tuesday, May 5, 2026.

now published at BMC Biology! rdcu.be/fdITD

Our latest publication is now out at Genome Biology! link.springer.com/article/10.1... We uncover a unique association between a H3K27me3 reader complex and active transcription. A thread with our key findings: (1/8) #TEsky #Polycomb #transcription #smallRNAs

A H3K27me3 reader complex couples H3K27me3 accumulation to nascent transcription of transposable elements in Paramecium - Genome BiologyBackground The ability to deposit histone H3K27-trimethyl (me3) marks is essential for transcriptional repression by Polycomb Repressive Complex 2 (PRC2). This is largely attributed to Polycomb repres...link.springer.com

Excited to announce the upcoming Jacques Monod Conference on the mechanistic and evolutionary basis of programmed DNA elimination (Sept 21–25, 2026): cjm.sb-roscoff.fr/en/conferenc... Organized by @laurarossevo.bsky.social and myself.

Happy to begin the year with the publication of a Journal Club article - Programmed ‘DNA splicing’ removes transposons from genes. rdcu.be/eXBym

Programmed ‘DNA splicing’ removes transposons from genesNature Reviews Molecular Cell Biology - A study that showed that programmed DNA elimination in somatic genomes of ciliates involves excision of intrusive, transposon-derived sequences from genes.rdcu.be

Excited to share our new preprint on BioRxiv! A collaborative effort spanning many years and several labs to uncover what the germline chromosomes of Paramecium really look like. 🔗 www.biorxiv.org/content/10.1... 1/5

The tiny germline chromosomes of Paramecium aurelia have an exceptionally high recombination rate and are capped by a new class of HelitronsBackground. Paramecia belong to the ciliate phylum of unicellular eukaryotes characterized by nuclear dimorphism. A diploid germline micronucleus (MIC) transmits genetic information across sexual gene...www.biorxiv.org

Our latest paper on a histone methyltransferase-independent function of PRC2 controlling small RNA dynamics during programmed DNA elimination in Paramecium is now published in #NAR. #RNAbiology #TEsky #smallRNAs #PRC2 #DNAelimination 1/5 academic.oup.com/nar/article-...

A histone methyltransferase-independent function of PRC2 controls small RNA dynamics during programmed DNA elimination in ParameciumAbstract. To limit transposable element (TE) mobilization, most eukaryotes have evolved small RNAs to silence TE activity via homology-dependent mechanismsacademic.oup.com