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James Connolly

Профиль Vively

MRC Career Development Fellow at Newcastle University. Studying how pathogens control their genes

Fantastic opportunity to join a brilliant lab and wider collaborative team!

Georgia Isom

Interested in joining our group in Oxford? We are looking for a PDRA with single particle Cryo-EM experience to help us figure out how sphingolipids are transported to the cell surface of Gram-negative bacteria. The deadline is 31st July. Informal enquires are welcome. Please share!

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Huge congratulations to @rhyswg.bsky.social and colleagues for this behemoth of a paper shedding light onto the mechanism of pyocins and their impact on cell function.

L-type pyocins inhibit the BAM complex to kill without cell entry - Nature CommunicationsL-type pyocins are a class of bacteriocin-like proteins with antibacterial activity. Here, the authors show that these proteins kill the pathogen Pseudomonas aeruginosa by inhibiting the BAM complex a...www.nature.com
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Very nice work on sugar transport during Proteus UTI

Selective sugar transport supports Proteus mirabilis fitness in the urinary tractAuthor summary All living organisms require nutrients to grow, survive, and cause disease. Bacteria like Proteus mirabilis, which causes urinary tract infections, rely on specialized systems to import...journals.plos.org
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Latest research from the lab out now. We examined the role and expression of fimbriae during UPEC bloodstream infection. A real team effort and brilliant collaboration with Mark Schembri’s lab in Brisbane. Thanks to the MRC and BBSRC for supporting our research @ukri.org

Yad fimbriae are triggered by host cues and enhance extraintestinal pathogenic Escherichia coli tissue colonisation during bloodstream infectionAuthor summary Extraintestinal pathogenic Escherichia coli (ExPEC) colonise the human gut without causing disease but can disseminate to the urinary tract and bloodstream. Understanding the mechanisms...journals.plos.org
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Congrats @natalia-los.bsky.social

Lis Lowe

First paper for PhD student in the Bolam / Lowe labs Natalia Łoś on a the characterisation of a new CBM family that binds (beta) mannan! #glycotime @natalia-los.bsky.social 🥳🥳 link.springer.com/article/10.1...

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Want to research the basis of how drug resistant bacteria interact with human immune cells? Fully funded 4-year PhD position available (UK home students). Come and join our amazing interdisciplinary team at the intersection of microbiology, immunity, metabolism and the clinic! Please spread the word

Hiding in plain sight: How a multi-drug resistant pathogen evades detection and killing by human neutrophils at Newcastle University on FindAPhD.comPhD Project - Hiding in plain sight: How a multi-drug resistant pathogen evades detection and killing by human neutrophils at Newcastle University, listed on FindAPhD.comwww.findaphd.com
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Fabulous opportunity

Melanie Blokesch

Open postdoc position in my lab on HGT and interbacterial competition. We seek candidates with a PhD in microbiology (or related fields)+ strong 1st-author publications. Curious, highly motivated, and dedicated team players ready to contribute fully are encouraged to apply. Details: tiny.cc/cz01101

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Well done team, I know how hard you have all worked on this!!!

Patrick Moynihan

We've been we've been working on this for quite a while now (hopefully published soon). Grateful to @proftracypalmer.bsky.social for concinving me & @lislowe.bsky.social that mycobacteria produce inter-bacterial toxins. Team science, led by @sambenedict5.bsky.social www.biorxiv.org/content/10.6...

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