Профиль

A childhood dream has come true – I was appointed Full Professor for Sustainable Biotechnology at the University of Düsseldorf @hhu.de : tinyurl.com/f43s74hp and as Director of the Institute for Molecular Enzyme Technology (IMET, www.iet.uni-duesseldorf.de/en/) at FZ Jülich @fz-juelich.de .

Mathematisch-Naturwissenschaftliche FakultätHeute ernannte Rektorin Prof. Dr. Anja Steinbeck den Biotechnologen Dr. Johannes Rebelein zum W3-Professor für Nachhaltige Biotechnologie. Rebelein wird damit auch Direktor des Instituts für Molekular...tinyurl.com

Very cool story about the efficient transport and incorporation of non canonical amino acid!

Our latest work on the nitrogenase-like methylthio-alkane reductase, which specifically reduces reduces carbon-sulfide bonds is now out @natcatal.nature.com: doi.org/10.1038/s419.... We find for the first time large #nitrogenase metalloclusters (P- and L-cluster) outside nitrogenases.

Methylthio-alkane reductases use nitrogenase metalloclusters for carbon–sulfur bond cleavage - Nature CatalysisMethylthio-alkane reductases are recently discovered enzymes that can produce methanethiol and small hydrocarbons from methylated sulfur compounds. Now the cryo-EM structure of a methylthio-alkane red...doi.org

Fantastic work by the Ward lab to repurpose cytochrome #P450 enzymes for a new-to-nature asymmetric metal-catalysed H atom transfer! Just released @Nature : doi.org/10.1038/s415.... A must read!🧪

Repurposing haemoproteins for asymmetric metal-catalysed H atom transfer - NatureCytochrome P450 enzymes can be repurposed to catalyse asymmetric metal–hydride hydrogen atom transfer, a new-to-nature reaction.doi.org

Great collaboration with @lennartschada.bsky.social on an #enzyme converting the #plastic component ethylene glycol and to a feedstock chemical for microbes. Offering new ways to use plastic biotechnologically. 🧪

I am honored and excited that our research on #nitrogenases and the conversion of #CO2 to hydrocarbons is highlighted in the Yearbook 2024 of the Max Planck Society, see page 29. An English and a German version of the Yearbook are available in www.mpg.de/13631298/yea....

Yearbook HighlightsThe Yearbook Highlights of the Max Planck Societympg.de

A must read for anybody interested in the evolution of life and how to construct phylogenies using structures. Outstanding work by @georghochberg.bsky.social and co-worker. Congrats!

Leveraging spectroscopic and structural approaches we obtained new insights into the role of #ferredoxins in N2 fixation. Just published in Chemistry – A European Journal: doi.org/10.1002/chem...! Great work by Holly Addison. Fantastic collaboration with Antonio Pierik on the EPR characterization.

Two Key Ferredoxins for Nitrogen Fixation Have Different Specificities and Biophysical PropertiesTwo ferredoxins, FdC and FdN, are collectively essential for the process of nitrogen fixation by the iron nitrogenase in R. capsulatus. We explore the biophysical factors, through spectroscopic and s....doi.org

Exciting work from @frunzkelab.bsky.social and @borjana-a.bsky.social at @fz-juelich.de

Exciting work by Ribbe & Hu lab demonstrating the in vivo reduction of N2 by L-cluster containing Nif(EN)2 inside E. coli: www.science.org/doi/10.1126/... This finding suggests a smaller minimal gene set for the heterologous expression of #nitrogenase and an easier route to synthetic #N2-fixation

Heterologous synthesis of a simplified nitrogenase analog in Escherichia coliHeterologous synthesis of a nitrogenase analog (NifH/NifEN) in E. coli enables N2 reduction and incorporation of N into biomass.www.science.org

Great work Adrian!

This is an excellent explanation about the implications of finding #nitrogenase #metalloclusters in the MCR activation complex

Had a blast at VAAM 2025 in Bochum @vaam-microbes.bsky.social. Holly Addison and Frederik Schmidt gave fantastic talks about our work electron transport to #nitrogenase and nitrogenase #catalysis

Very proud to see my first PhD student defend his thesis @mpimicrobiomarburg.bsky.social ! Congrats to Leonard Ernst 🎊🍾🎉🥳

Come and join us in Marburg

Two exciting papers about the the protection of nitrogenases from O2 by the ferredoxin Shethna protein II from the Tezcan doi.org/10.1038/s415... and Einsle doi.org/10.1038/s415... labs were published today by @nature.com. Surprisingly both papers reveal superstructures of nitrogenase filaments.

Structural basis for the conformational protection of nitrogenase from O2 - NatureCryo-electron microscopy of Azotobacter vinelandii FeSII–nitrogenase reveals a core complex of molybdenum–iron proteins (MoFePs), iron proteins (FePs) and FeSII, in which FeSII mediates interactions w...doi.org

I am honored to be selected as EMBO Young Investigator 2024. Thank you to my students, lab members and collaborators who made this success possible! www.embo.org/press-releas...

EMBO announces new Young Investigators – Press releases – EMBO26 new additions to the EMBO Young Investigator Programme join a community of more than 700 current and former awardeeswww.embo.org