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Very pleased to finally share the main story from my PhD, now published in @natcomms.nature.com ! 🎉 Using a sea anemone we discovered and characterised epithelial cell extrusion as the mechanism underlying starvation-induced cell loss. 🔗 Open-access article: www.nature.com/articles/s41...

Epithelial cell extrusion underlies starvation-induced cell loss in a sea anemone - Nature CommunicationsEpithelial cell extrusion in a sea anemone shares key hallmarks with bilaterians and is dynamically regulated by nutritional status. During starvation-induced body shrinkage, extrusion likely contribu...www.nature.com

Very happy to share our new review on visual computation in the cephalopod brain, with @vangeliqueallen.bsky.social, out now! We discuss exciting recent advances in understanding how the radically different brain of cephalopods processes the visual scene. 🐙🔬👀 www.sciencedirect.com/science/arti...

Sailing in @biorxivpreprint.bsky.social ready for summer, our study on the iconic Portuguese man o' war 🪼 is out: www.biorxiv.org/content/10.6.... We use (epi)genomics to understand a critter that fascinates me since childhood. Massive team effort with @obog.bsky.social, Cummins and Neely groups. 🧵

Happy to share the final version of our study on the evolution of chromatin states across eukaryotes, out today in @natgenet.nature.com Led by @crisnava.bsky.social and @seanamontgomery.bsky.social www.nature.com/articles/s41... Some highlights below

Diversity and evolution of chromatin regulatory states across eukaryotes - Nature GeneticsThis study introduces iChIP2, a low-input chromatin immunoprecipitation followed by sequencing method that profiles histone post-translational modifications (hPTMs) simultaneously across diverse eukar...www.nature.com

If you are interested in nervous system evolution you may want to read our review with Kei Jokura on nerve nets: "Revisiting nerve nets: functional organization and evolutionary implication" https://link.springer.com/article/10.1038/s44318-026-00879-w […] [Original post on biologists.social]

Ruibao's first paper from the lab is out in @nature.com . www.nature.com/articles/s41.... Collab with @multicellgenome.bsky.social & @jennahed.bsky.social. How did cells stick together and form the first animals? The protist Ministeria suggests cellular aggregation had a role. @iuqcb.bsky.social

A unicellular relative links aggregative multicellularity to animal origins - NatureAggregative multicellularity was key to the evolution of the multicellular animal genetic toolkit.www.nature.com

We're hiring 4 postdocs at @unibo.it to study nervous system evolution. Seeking expertise in single-cell genomics, molecular or developmental biology in ctenophores, cnidarians, echinoderms, flies or human stem cells. 2+2 yrs contract. Deadline: 26 Aug. Please share! bandi.unibo.it/s/apos7/proc...

Procedura di valutazione comparativa per titoli e colloquio per il conferimento di n. 4 contratti di ricerca presso il Dipartimento di Scienze Biologiche, Geologiche e Ambientali - SSD BIOS-04/A - GSD...bandi.unibo.it

New preprint! www.biorxiv.org/content/10.6... Nearly a decade after starting the project, the first major results from our comparative connectomics work is online! Comparing the head direction circuits of the central complex in bees, ants and flies, recapitulating >300million years of evolution.

Grateful to receive support from the ANR @agencerecherche.bsky.social for our collaborative project MiRiFIC with G. Michaux (Univ. Rennes) 🙏 We will explore subcellular regeneration through evolution.

'The Decline & Fall of the Human Empire', now in paperback in a land misruled by ignorant warlords. where pestilence scythes its way unchecked across the burning land, and purveyors of knowledge are persecuted like witches. Also, Canada.

📢 JOB ALERT! 📢 I am recruiting a 30-month postdoc to work on modelling the vision of trilobites @hfspo.bsky.social ! If you like 3D data, fossils, and functional morphology, this is the one for you! 📆Deadline 27. Aug Pls contact me with any Qs and share widely! www.bristol.ac.uk/jobs/find/de...

New paper from the lab out! How did animals move repeteadly from water to land? We compared ca. 1,000 animal genomes across the animal kingdom to ask whether evolution reused the same genomic solutions. The answer: same challenge, but many genomic routes 🧵1/n www.nature.com/articles/s41...

Happy Monday! Come learn how jellyfish swim. In a review led by fluid dynamics maestro Alex Hoover, we outline how neuromechanical modeling will help us understand how modulation of neural activity allows jellyfish to jet and pirouette through fluids www.sciencedirect.com/science/arti...

Excited to share a new preprint from the lab, by @andrewmatheson.bsky.social and team, where we dive into the superpower of newts: plasticity! www.biorxiv.org/content/10.6... Like many good projects, this started with a serendipitous observation... 🧵1/5

Postdoc Positions: Coral Cell and Molecular Biology Reach out directly to mg2@stowers.org or follow the link below to read more and apply through the institute portal! Postdoctoral Research Associate - REQID0002557 www.stowers.org/careers/post...

Postdoctoral Research Associate - REQID0002557If you have a collection of outstanding people who ask really interesting questions, like each other and push the envelope, important discoveries will…www.stowers.org

Our review paper on nerve nets has just been published!! @jekely.biologists.social.ap.brid.gy

Neuronal circuits are assembled using a repertoire of different chemical and electrical synapses, with the latter connecting the cytoplasm between two neurons. Anne Martin asks how this complex process develops, finding proteins that bridge both synapse types. #2026SDB Preprint⤵️

Electrical synapse molecular diversity revealed by proximity-based proteomic discoveryNeuronal circuits are composed of synapses that are either chemical, where signals are transmitted via neurotransmitter release and reception, or electrical, where signals pass directly through intern...www.biorxiv.org

New preprint alert from the Watanabe lab!! Have you wondered what microglia are surveying with their motile processes? Have you wondered what happens to proteolytic organelles that are stuck in axons? Check this out! Microglia are the garbage man! www.biorxiv.org/content/10.6...

Microglia extract neuronal proteolytic organelles via skoupocytosisNeurons face unique challenges in maintaining protein homeostasis due to their tortuous morphology and extended processes. Proteolytic organelles are typically transported retrogradely towards their s...www.biorxiv.org

Great work by PhD student Patricio Ferrer Murguia. His paper reporting the twist mutant in Nematostella is out: doi.org/10.1242/dev.... twist is required to form secondary tentacles, via localized FGFR and mTOR signaling. Later, mutants form stunning epithelial neoplasia with tentacle identity.

Check the brilliant work by Sanjay Narayanaswamy in Nature Comm. www.nature.com/articles/s41.... He established a scalable Gastruloid protocol and showed that in gastruloids of Nematostella axial polarity and germ layer restoration and sorting depends on a Notch-Wnt signaling feedback loop.

Notch coordinates self-organization of germ layers and axial polarity in sea anemone gastruloids - Nature CommunicationsHere they show that gastruloids made of embryonic cells of the sea anemone Nematostella can robustly regenerate whole organisms. They show that Notch signaling is crucial to sort out the randomly disp...www.nature.com