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Профиль

Paul Hoskisson 🧫 🦠🐸

Профиль Vively

Professor of Molecular Microbiology, Fellow of the Royal Society of Edinburgh, Editor at Microbial Genomics & mBio, Scouse, interested in Streptomyces, Evolution, Antibiotics, AMR, microbiology, Phage, herpetology, Cricket, EvertonFC

Couple of gorgeous Adders (Vipera berus) from this mornings walk - always a joy to see these

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really lovely piece of work from @raufs.bsky.social et al., Complex multicellularity is linked with expanded specialized metabolite production in microorganisms www.nature.com/articles/s41...

Complex multicellularity is linked with expanded specialized metabolite production in microorganisms - Nature MicrobiologyThe evolutionary emergence of complex multicellularity in bacteria and fungi, such as the ability for mycelial growth, is strongly associated with increased genomic carriage of biosynthetic machinery ...www.nature.com
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this is very cool - Chemical ecology and convergent evolution of natural hallucinogens: From ecological defense to conserved neural targets www.pnas.org/doi/10.1073/...

PNASProceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...www.pnas.org
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Cool new preprint of a new defence family! Antimicrobial-resistance plasmids encode Evangelion, a widespread DUF4062 anti-phage defence family www.biorxiv.org/content/10.6...

Antimicrobial-resistance plasmids encode Evangelion, a widespread DUF4062 anti-phage defence familyMany bacterial anti-phage defence systems are encoded by mobile genetic elements, yet much of this antiviral repertoire remains undiscovered. Antimicrobial-resistance plasmids are well known for disse...www.biorxiv.org
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First ‘Charles Darwin’ Rose of the year has opened in the garden!

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This is an awesome review from @sheppardlab.bsky.social - Epistasis and co-adaptation in bacterial genome #evolution www.nature.com/articles/s41...

Epistasis and co-adaptation in bacterial genome evolution - Nature Reviews GeneticsBacterial genome evolution is shaped by epistasis, which can constrain or promote specific evolutionary paths. The authors review how integrating the effects of epistatic interactions into population-...www.nature.com
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Recently back from an amazing #Herping trip to #Albania and managed to see Europes smallest and rarest Viper - the Greek Meadow Viper (Vipera graeca), lots of careful searching at 1900 metres resulted in finding a beautiful, sub-adult female

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wow- The evolution of high-order genome architecture revealed from 1,000 species www.cell.com/cell/abstrac...

The evolution of high-order genome architecture revealed from 1,000 speciesComparative Hi-C analysis across 1,025 species reveals that genome architecture has evolved along distinct trajectories, with plants favoring global folding and animals developing checkerboard compart...www.cell.com
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#Academia is essentially, repeatedly adding the same information in to a range of different forms on a daily basis

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Mind blown! 🤯 Spontaneous problem-solving in bumble bees www.science.org/doi/10.1126/...

Spontaneous problem-solving in bumble beesProblem-solving using novel solutions without explicit training is often considered a hallmark of cognitive flexibility. We investigated whether bumble bees (Bombus terrestris) could solve a novel obj...www.science.org
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Island-Hopping Frogs: How Geology, Ocean Currents and Evolution Shaped Biodiversity in the Pacific www.linnean.org/news/2026/04...

Island-Hopping Frogs: How Geology, Ocean Currents and Evolution…Discover the latest news from The Linnean Society of London.www.linnean.org
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@countryman100.bsky.social rooting for you guys tonight!

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Evolution of genome-wide barriers to gene flow during complex speciation in rattlesnakes - www.pnas.org/doi/10.1073/...

PNASProceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...www.pnas.org
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This is cool - ‘Descent from a common ancestor restricts exploration of protein sequence space’ - www.pnas.org/doi/10.1073/... & a great commentary piece too- ‘Maynard Smith’s analogy, realized: Common ancestry constrains evolutionary percolation through protein space’ www.pnas.org/doi/10.1073/...

PNASProceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...www.pnas.org
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This is a really cool study - Convergent evolution of aerobic fermentation through divergent mechanisms acting on key shared glycolytic genes link.springer.com/article/10.1...

Convergent evolution of aerobic fermentation through divergent mechanisms acting on key shared glycolytic genes - The EMBO JournalAs the tree of life becomes increasingly accessible to molecular investigations, describing mechanisms underlying evolutionary convergence and constraint will be crucial to understanding diversificati...link.springer.com
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Come and study for a PhD with us on antibiotic-producing Streptomyces, trying to understand the roles of primary metabolic enzymes with additional cellular roles - Details below - please repost www.findaphd.com/phds/project...

Primary metabolic enzymes in antibiotic-producing Streptomyces bacteria, but not as we know them! at University of Strathclyde on FindAPhD.comPhD Project - Primary metabolic enzymes in antibiotic-producing Streptomyces bacteria, but not as we know them! at University of Strathclyde, listed on FindAPhD.comwww.findaphd.com
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Cool paper from the ISBA collection (www.microbiologyresearch.org/content/adva... ) from @evodivmet.bsky.social et al Functional shifts of the dual-substrate phosphoribosyl isomerase PriA from primary to specialized metabolism in rare Actinomycetota www.microbiologyresearch.org/content/jour...

www.microbiologyresearch.org
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Really cool work from @mblokesch.bsky.social et al Competence-mediated DNA uptake diversifies Vibrio cholerae sedentary chromosomal integrons www.science.org/doi/10.1126/...

Competence-mediated DNA uptake diversifies Vibrio cholerae sedentary chromosomal integronsBacteria often survive viral attack and environmental stress by sharing genes that enhance their defenses. The cholera pathogen Vibrio cholerae carries a sedentary chromosomal integron (SCI), a genetic element containing hundreds of mostly promoterless ...www.science.org
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@christianlandry.bsky.social thanks for the SMBE talk today Christian, wonderful work!

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