Профиль

Nick Loman

Профиль Vively

Public health (meta)genomics & bioinformatics, Prof @unibirmingham.bsky.social, Director @imibirmingham.bsky.social & @climb.ac.uk

6 тыс. подписчиков706 подписок692 публикаций
⟳ Репост от Nick Loman
Peter Tennant

Peter's Law of Chatbot Accuracy*: "everything you read that's produced by an LLM is absolutely true, except for the rare output about which you happen have expert knowledge". *Remixed from Knoll's Law of Media Accuracy, where the exact same rules apply!

By Cory Doctorow (GPG 0xBF3D9110957E5F4C)

AI is a normal tech. That means there are times when it is useful and times when it is pointless or actively harmful. One rule of thumb for chatbots is that they can only provide useful information to experts who have the discernment to ignore the defective output that LLMs *always* emit. 60/

⟳ Репост от Nick Loman
John Lees

What is an 'everyday task' and what is a 'complex problem' in bioinformatics software engineering? Feels more important use the right model now they're not so heavily subsidised! I did a small comparison on an optimisation task: johnlees.me/posts/ska2-c... Small/cheap model wasn't good enough

Credit use of AI models for bioinformatics: a tiny benchmarkAgentic coding models such as codex and claude code are really useful for software engineering tasks. We sadly (and unsurprisingly) seem to be exiting the era of highly subsidised costs to get us hook...johnlees.me
⟳ Репост от Nick Loman
Andrew Rambaut (🐏🎀)

This is so important - allowing individual uses of data to be tracked as citations will be so useful for demonstrating impact and reach of genome data. When you use data from Pathoplexus, create a SetSet & DOI for the sequences used and cite it in your paper.

Pathoplexus

2/ 📄 SeqSets/DOIs now show citations! We've integrated with @crossref.bsky.social so you can see which scientific publications have used a SeqSet - on the SeqSet page *and* on individual sequence pages. Using seqs in a paper? Don't forget to cite the DOI! 👉 pathoplexus.org/about/citation

⟳ Репост от Nick Loman
By Cory Doctorow (GPG 0xBF3D9110957E5F4C)

"An insecure sandbox is not a demonstration of cyberprowess." -Loren Kohnfelder (on Openai's model "escaping containment" and attacking Hugging Face's servers) designingsecuresoftware.com/writings/com...

Normalizing cybersecurity facepalmsOpenAI writes: “Last week, Hugging Face disclosed a new kind of security incident⁠(opens in a new window) after they detected and contained an AI agent that compromised their infrastructure, something...designingsecuresoftware.com
⟳ Репост от Nick Loman
Sorek Lab

Our paper out in Science today: The Metis defense system senses molecular byproducts released when a phage degrades the bacterial genome, and then prevents replication of the phage in the infected cell Congratulations @ostermanilya.bsky.social and co-authors!

Bacteria sense virus-induced genome degradation via methylated mononucleotidesPhages often degrade the genome of their bacterial host to individual nucleotides. Here we describe Metis, a bacterial defense system that directly senses phage-mediated host genome degradation. Metis...www.science.orgOsterman Ilya

Excited to share that our Metis story is now published in Science! 🎉 Bacteria can sense phage-induced degradation of their genome and activate immunity. Many thanks to everyone who contributed to this work. 📄 www.science.org/doi/10.1126/... More details in my earlier thread 🧵⬇️

⟳ Репост от Nick Loman
Kristian G. Andersen

Important post on the ongoing Bundibugyo outbreak in DRC/Uganda. The clock appears to be fairly well-calibrated by now, even if a little slower than what we might have expected. Timing ~early-mid March and a bit of uncertainty re. 1 or possibly 2 intros. virological.org/t/genomic-ep...

Genomic epidemiology of the ongoing 2026 Bundibugyo Virus Disease outbreak in the Democratic Republic of the CongoGenomic epidemiology of the ongoing 2026 Bundibugyo Virus Disease outbreak in the Democratic Republic of the Congo Institut National de Recherche Biomédicale (INRB), Kinshasa – DRC and partners Conte...virological.org
Следующие публикации