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Chloé Baum @chloebaum.bsky.social leads the wet-lab team at Institut Pasteur's Biomics. With the PromethION 2 Integrated, she sequences full-length dengue & chikungunya genomes in a single read and runs 96 bacterial genomes per flow cell. #Genomics Interview ↘️ nanoporetech.com/blog/advanci...
In zebrafish, neural stem cells keep producing neurons throughout life. Pasteur scientists reveal how Notch3 signaling coordinates neighboring stem cells to maintain this balance, insights relevant to brain tumours. www.pasteur.fr/en/research-... @natcomms.nature.com #Neuroscience #StemCells
How Brain Stem Cells Coordinate to Produce NeuronsIn many vertebrates, brain stem cells produce neurons throughout life. A team of scientists has revealed for the first time the molecular mechanisms by which adult neural stem cells communicate with o...www.pasteur.frInstitut Pasteur researchers developed "optonanobody": a light-controlled nanobody targeting α7 nicotinic receptors. Switch receptors on/off with light, no genetic editing needed. New research tool for Alzheimer's, Parkinson's & schizophrenia. #Neuroscience ↘️ pubs.acs.org/doi/10.1021/...
An Optonanobody for Reversible Photoactivation of Recombinant and Native α7 Nicotinic ReceptorsPhotopharmacology, which enables the precise optical control of endogenous receptor activity, represents a powerful approach in neuroscience. However, photochromic diffusible ligands often exhibit lim...pubs.acs.orgInstitut Pasteur researchers describe LIN codes in PLOS Biology: a standardized numerical system for identifying bacterial strains from genome data, now used in BIGSdb-Pasteur and Pathogenwatch for outbreak surveillance. @sylvainbrisse.bsky.social ↘️ doi.org/10.1371/journal.pbio.3003781
Life Identification Numbers: A strain nomenclature approach to aid epidemiological surveillance of bacterial pathogensUnified bacterial strain taxonomies are needed for coherent communication of findings in microbiological research. This Essay provides an overview of a novel bacterial strain taxonomy and describes ho...doi.orgQuantifying how multiple transmission routes contribute to the spread of HTLV-1 in different endemic foci: a mathematical modelling study @scauchemez.bsky.social ↘️ www.sciencedirect.com/science/arti...
L'Institut Pasteur et l'IRD ont signé ce mardi un nouvel accord-cadre de 5 ans, troisième génération depuis 2010. Priorité commune : les maladies vectorielles et zoonotiques, du laboratoire au terrain, face aux changements climatiques. 🤝 @ird-fr.bsky.social
The brain's immune sentinels (microglia) & its protective walls (blood-brain barrier) build each other during embryogenesis. Morgane Thion's @morganethion.bsky.social G5 investigates this critical crosstalk and its role in neurological vulnerabilities. ➡️ www.pasteur.fr/en/research-...
How do cells "hibernate"? Deep-sea archaea (100°C, 40 MPa) hold the answer. Scientists identified a protein controlling ribosome dormancy, also found in human gut archaea. Nature Communications #Archaea ↘️ www.pasteur.fr/en/press-are...
🔬 Meet Spyros Lytras, one of our new G5 group leaders! Using AI to predict viral protein evolution, he's designing vaccines for strains that don't yet exist. No more waiting for threats to emerge—be ready ahead of time. The future of pandemic preparedness. 🧬 📖 www.pasteur.fr/en/research-...
Predicting viral evolution with AISpyros Lytras is one of four young scientists selected in 2025 to lead new research groups at the Institut Pasteur. He has headed the “Antigen Evolution & Design laboratory” 5-year Group (G5) since Ju...www.pasteur.frCongratulations to Shahragim Tajbakhsh on his #ERCPoC grant for StemAAV, a project aiming to target muscle stem cells for more durable gene therapies in Duchenne muscular dystrophy and other myopathies. Led with Brendan Evano @brendan-evano.bsky.social 🇪🇺👨🔬 @erc.europa.eu pa.eu
⚠️The current Bundibugyo Ebola outbreak in DRC & Uganda is one of the largest on record. With no vaccine or treatment, early detection & conventional public health measures are critical. Institut Pasteur's Reference Center & OITF are mobilizing to support the response. www.pasteur.fr/en/research-...
2026 Ebola Outbreak in the Democratic Republic of Congo and Uganda: Everything You Need to Know About BundibugyoSince March 2026, an Ebola outbreak caused by the rare Bundibugyo species has been striking the Democratic Republic of Congo (DRC) and spreading to Uganda. With more than 827 confirmed cases and 194 d...www.pasteur.frDiscover how gut, vaginal & skin microbiota shape immunity, mental health & well-being. Meet IM2P—Institut Pasteur's bold new program uniting top institutes to turn microbiome discoveries into clinical breakthroughs. 🔬 📖 www.pasteur.fr/en/research-...
How our microbiota affects our healthThe microbiome, the invisible jungle that inhabits our body, is much more than a mere collection of bacteria, viruses, fungi, or parasites: it is a vital ecosystem that shapes our health, our immunity...www.pasteur.fr🇫🇷🇰🇷 Marking 140 years of Franco-Korean diplomatic ties, Institut Pasteur & Institut Pasteur Korea unveiled a new scientific chapter with an international symposium on vaccine innovation & AI-driven antibiotic development. Strong partnership ahead! 🔬 www.pasteur.fr/en/press-are...
Institut Pasteur Korea and the Institut Pasteur Open a New Chapter in Strategic Collaboration- New agreement and Scientific Liaison Committee to advance joint research and researcher exchange –Institut Pasteur Korea (IPK) is strengthening its strategic partnership with the Institut Pasteur (I...www.pasteur.fr🎵 Universal beat: Study reveals that 98 animal species—from insects to great apes—share a common vocal rhythm of ~2.8 Hz. This ancient constraint reflects how brains process sound & may facilitate cross-species communication! 🧠 www.pasteur.fr/en/press-are...
The universal tempo of animal communicationA team from UNIGE, NCCR Evolving Language, reconnect and the Institut Pasteur shows that the vast majority of animal species have been vocalising at a shared rhythm for hundreds of millions of years.-...www.pasteur.frCongrats @baptistedarracq.bsky.social & @marialopopolo.bsky.social two Pasteurians awarded the Academy of Sciences' "Major Advances in Biology" Prize for groundbreaking Science publications on bacterial defense & ancient leprosy. pubmed.ncbi.nlm.nih.gov/40339013/ pubmed.ncbi.nlm.nih.gov/40440428/
Sedentary chromosomal integrons as biobanks of bacterial antiphage defense systems - PubMedIntegrons are genetic systems that drive bacterial adaptation by acquiring, expressing, and shuffling gene cassettes. While mobile integrons are well known for spreading antibiotic resistance genes, t...pubmed.ncbi.nlm.nih.govSkin bacteria are not just bystanders in hidradenitis suppurativa. New @embomolmed.org research from Institut Pasteur shows Porphyromonas uenonis penetrates skin, sparks inflammation and triggers an autoimmune attack on skin tissue. #HidradenitisSuppurativa
Hidradenitis suppurativa: skin-colonizing bacteria play an unexpected roleScientists have revealed that normally harmless Porphyromonas uenonis bacteria play an active role in triggering inflammation and autoimmunity in patients with hidradenitis suppurativa. This discovery...www.pasteur.fr🧬 A 10‑year follow‑up of the Milieu Intérieur cohort reveals shifts in immune responses including CMV seroreversion and shows early blood transcriptional profiles can predict later infection. A unique window into immune aging & health. www.nature.com/articles/s41... @darraghduffy.bsky.social
An integrative approach for studying immunological variation in an aging population – The Milieu Intérieur follow-up study - Nature CommunicationsThe human immune system and response shows variability between people due to both genetic and environmental factors. Here the authors present a follow up of the Milieu Intérieur study applying an inte...www.nature.com🦠 Join the 27th National Infectious Diseases Days (JNI 2026), June 18‑20 at the Palais des Congrès, Paris! Health pros, researchers & students will explore new therapies, threats & public health challenges. 🔗 Register here: anrs.fr/actualites/a... @anrs-mie.bsky.social
27es Journées Nationales d'Infectiologie - ANRS MIEÀ l’occasion des Journées Nationales d'Infectiologie 2026, l’ANRS MIE anime une session en partenariat consacrée au Mpox, Ebola, Marburg.anrs.fr