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Профиль

Adam Mulkern

Профиль Vively

Postdoc, MacLean lab, experimental evolution | University of Oxford

Why do some bacteria evolve antibiotic resistance more readily than others? Loved writing this one with @craigmaclean.bsky.social and Liam.

Craig MacLean

New Essay: 'Resistance potentiators: Evolutionary catalysts of antibiotic resistance' To understand the evolutionary drivers of #AMR we need to move beyond resistance genes to thinking about the ability of genomes to generate AMR variants. #microsky journals.plos.org/plosbiology/...

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Really grateful to receive an MPLS Travel Award to visit Copenhagen this week. Gave talks at DTU - Technical University of Denmark and Københavns Universitet - University of Copenhagen on polyclonal P. aeruginosa interactions and got to meet some brilliant people working on AMR. Great few days!

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Still buzzing after the @microbiologysociety.org meeting on 'Understanding and Predicting Microbial Evolutionary Dynamics' last week. It was great to connect with so many people who share the same type of science. Big thanks to the organisers for the opportunity to present my research too!

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Had a short but sweet visit to Zürich to speak at @ethz.ch. Many thanks to @phagemuffin.bsky.social and @aharms485.bsky.social!

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What a month...I spent June in the US at the @cshlnews.bsky.social Advanced Bacterial Genetics course and then the GRC Molecular Mechanisms in Evolution! I met so many cool people along the way — special shoutout to my course lab partner, Max!

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Hopped over to Northern Ireland last week to give a talk at @qubelfastofficial.bsky.social for their AMR seminar series. Thanks very much to @rwheatley8.bsky.social, @lindaoyama.bsky.social, and @sharonhuws.bsky.social for hosting me!

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Wrapped up 2024 with the @typaslab.bsky.social in Heidelberg @embl.org, doing some evolution experiments with @stefanbassler.bsky.social. Had an incredible time and looking forward to an exciting year of science in 2025!

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Excited to share something from my previous postdoc with @mgalactus.bsky.social, a collaboration with the lab of Jörg Vogel using lab evolution to see how different bacterial species develop resistance to programmable antibiotics:

A systematic identification of resistance determinants to antisense antibiotics suggests adaptation strategies dependent on the delivery peptideThe rise of antimicrobial resistance (AMR) among human pathogenic microbes is a serious threat to global health, calling for the development of novel treatment strategies. Antibiotics based on program...www.biorxiv.org
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Thanks to @rwheatley8.bsky.social for organising a lovely AMR & Microbiome workshop @magdalenoxford.bsky.social