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Take a look at our new paper on the structure of the EHD2 that, upon oligomerization, forms rings that remodel the plasma membrane and form caveolae. Beautiful work by Elena, Vasya @vasiliimikirtumov.bsky.social, Jeff & Oliver Dumke's team; take a look: www.nature.com/articles/s41...

Good day, everyone! We are looking for a technician to join our lab in Berlin. If you know anyone or want to apply, click the link. Starting time: soon. jobrxiv.org/job/max-delb...

Technical Assistant / Laboratory ManagerPost a job in 3min, or find thousands of job offers like this one at jobRxiv!jobrxiv.org

It's always a pleasure giving a talk and visiting ETH Zurich @ethz.ch. Fantastic campus with excellent science, thank you for having me !

New paper from the group! We were curious if the longevity of naked mole-rats has anything to do with their protein synthesis machinery. It was shown that the ribosomal 28S is split into 3 subunits Our cryo-EM study of the NMR ribosomes by @mehmetguel.bsky.social etal www.nature.com/articles/s41...

Cryo-EM structure of the naked mole-rat ribosome reveals a stabilized split 28S rRNA - Nature CommunicationsThe long-living rodent naked mole-rat has a distinct break in its 28S ribosomal RNA. Here, the authors present cryo-EM structures showing this cleavage is stabilized by surrounding ribosomal proteins,...www.nature.com

Went to a wonderful GRC on 3dem and discovered a new GPCR structure!! It has alpha helical resolution and it's an inactive state

Take a look at the fresh post-Easter paper about lipid regulation of NS5A, a key protein of the hepatitis C virus. We were happy to contribute to the all-star team by Anna, Rebecca, James et al, spearheaded by Christoph Welsch. www.science.org/doi/10.1126/...

Phospholipid-driven conformational switching of HCV NS5A links protein folding to replication membrane remodelingA host lipid flips a viral protein’s shape to control membrane remodeling during virus replication.www.science.org

Quantum Computing once felt like a distant academic dream. In 2001, I was excited by a QC factorizing 15; today, it tackles challenging problems in science! ⚛️🧬 I’m excited to invite y'all to the Helmholtz Quantum Conference in Berlin, July 9–10, 2026. 🔗 Details: events.hifis.net/event/3513/o...

Helmholtz Quantum Conference 2026Helmholtz Quantum is supporting innovative research projects that translate quantum technologies into concrete applications. The Quantum Use Challenge aims to realise the potential of quantum computin...events.hifis.net

This is one amazing conference!!

Wish everyone a New Year resolution of 2-3 Ångström!!!

Well, that's one way to look at it. Although I am sure that people with dedication would also take a coffee shop job way too seriously and will be amazing in it! Academia is just a job | Nature Human Behaviour share.google/7IQ3wak0pmOS...

Academia is just a job - Nature Human BehaviourWorking in academia can be stressful. Laurel Raffington suggests treating it as ‘just a job’ to reduce performance pressure and advocate for structural improvements.share.google

We got a large Helmholtz Bioengineering grant with Oliver Daumke, Artur Yakimovich, Alina Bazarova, and Dietrich Ruess to use protein design to target cancer. Five open postdoctoral positions in Generative AI & Protein Engineering. Share & apply! jobrxiv.org/job/max-delb...

Postdoctoral Positions in Protein EngineeringPost a job in 3min, or find thousands of job offers like this one at jobRxiv!jobrxiv.org

We have a new preprint for you. Naked mole rats are very long-lived rodents and have increased translational fidelity. Interestingly, 28S ribosomal RNA is split. Here we investigated the structure of the ribosome by single particle cryo-EM. Take a look. www.biorxiv.org/content/10.1...

Cryo-EM structure of the naked mole-rat ribosome reveals a stabilized split 28S rRNAThe naked mole-rat (Heterocephalus glaber) is a long-lived mammal with remarkable resistance to cancer and hypoxia, suggesting the evolution of robust proteostasis networks. The ribosome, the central ...www.biorxiv.org

Group Leader in Biomedical Engineering at the @mdc-berlin.bsky.social in Berlin. It's a broad call for whoever is doing exciting Bioengineering, please apply or share. We have a great institute with amazing colleagues and core facilities,highly recommend application.mdc-berlin.de/site/index.p...

We have a preprint of a book chapter for you: Structural Analysis of Membrane Proteins in Cell-Derived Microvesicles. We describe how to image membrane proteins in mid-sized vesicles using cryo-electron tomography zenodo.org/records/1717...

I'd say it's a paper of the week if not a year Lithium deficiency and the onset of Alzheimer’s disease www.nature.com/articles/s41...

Lithium deficiency and the onset of Alzheimer’s disease - NatureLithium has an essential role in the brain and is deficient early in Alzheimer’s disease, which can be recapitulated in mice and treated with a novel lithium salt that restores the physiological level...www.nature.com

Postdoc program at the MDC in Berlin, @mdc-berlin.bsky.social : take a look 👇👇 For this call, collaborative projects between two groups will be funded. Take a look at the call and the groups and drop me an email if interested. Share with colleagues too! www.mdc-berlin.de/postdocs#t-g...

Building atomic models to cryo-EM maps of huge molecules is intimidating: crowded, uncertain copy numbers, variable resolution ... Fan Liu and team incl us, show how cross-linking MS can be used to build novel models of unknown complexes, like a giant Melbourne virus biorxiv.org/content/10.1...

We have a preprint for you EHD2 forms rings on caveolae necks, in contrast to most EHDs forming helices. We determined its structure on membranes and show that N-term acts as a spacer By Elena, Vasya @vasiliimikirtumov.bsky.social, Jeff &Oli Daumke www.biorxiv.org/content/10.1...

It's fellowship season in the EU. If you want to talk and join our group at the amazing MDC in Berlin on a fellowship, please write me an email. We do cryo-EM/ET, membrane proteins, data science/AI, our work: scholar.google.com/citations?so... Fellowships: Marie Curie, EMBO, HFSP, Humboldt...

Our contribution to Mohit Misra, Ivan Đikić, and Co's stellar research on how a pathogenic bacterium, Legionella pneumophila, hijacks host cell signaling It was a huge effort and took many years to combine all the data and methods, so enjoy reading👇 www.researchsquare.com/article/rs-6...