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A truly great collection of webinars about #placebo and #nocebo in many different contexts. The brightest minds - established experts and shooting stars - present their work. Recommend! From @sfb-trr-289.bsky.social @sipsplacebo.bsky.social @placebosydney.bsky.social @kingsioppn.bsky.social

We looked at a global cohort of >145,000 patients with a record of FND in the last 30 ys in TriNetX: confirmed frequent comorbidities and outcomes often worse than in MS. Read in JAMA Neurology: tinyurl.com/yc4wfyaj Open access to the accepted manuscript: osf.io/rwtnp @fndsociety.bsky.social

Comorbidities and Outcomes in People with Functional Neurological DisorderThis cohort study compared the prevalence of neurological comorbidities among people with functional neurological disorder versus those with epilepsy and multiple sclerosis.jamanetwork.com

These two papers in Lancet Psychiatry about placebo/nocebo in practice and in trials are very worth reading. Be mindful about expectation in your patients/yourself, and critical even with RCTs. I hope reporting on placebo conditions, treatment expectations and blinding success improves steadily!!

Interesting approach to avoid unblinding for a study on efficacy of psychotropic components. Just sedate them before giving the verum/placebo! I assume the setting & session with propofol alone might have large placebo effects, so sample size might be critical.

Call for papers for a collection on placebo and nocebo effects in psychiatry - excellent! @sipsplacebo.bsky.social @timnicholson.bsky.social @devinterhune.bsky.social @labasedow.bsky.social @bnpa.bsky.social @sfb-trr-289.bsky.social

Milestone for FND care in Germany: first guideline on functional motor disorder, published by German Neurol. Society. I contributed to comorbidities, pharmacotherapy & placebo/nocebo. Hope it's a valuable resource for clinicians & support people living with FND. register.awmf.org/de/leitlinie...

Finally a prospective study & spotlight on functional sensory symptoms! Congrats to the authors for this diligent, comprehensive & thoughtful work. Great to read qualitative analyses of symptom descriptions as well. Next up - pain in FND..! @braincomms.bsky.social

Exciting research from Mirta Fiorio on placebo effects in the motor domain. She also experimentally probes predictions & bayesian integration in motor FND - can't wait to learn more from her on this in the future!

@popkirov.bsky.social delivers yet another fantastic instructive clinical overview on FND at the @dgn-ev.bsky.social conference (second largest national neurologists' society in the world). Packed audience, most attendees of the whole event. Amazing

@8minutesold.bsky.social and others - cool project - and check our the page! Maybe a cool Sci Fi story from #cosmicchoreographies?!

SIPS snippet #4: It's so important to study patients directly to understand pain. So far, patient data seem to challenge the bayesian integration principles in pain. But we need a clearer picture - just as the work from Eleonora Camerone is striving to do! #SIPSplacebo2025 @sipsplacebo.bsky.social

SIPS snippet #3: Excited that we have people with lived experience at this conference @sipsplacebo.bsky.social The patient advisory board from Germany @sfb-trr-289.bsky.social has a poster today (Tues), no 88! Everyone at #SIPSplacebo2025 go check it out

SIPS snippet #2: Mirta Fiorio talking at #SIPSplacebo2025 about placebo mechanisms in motor system - important topic in neurology! And: Expectation & placebo/nocebo mechanisms are highly relevant in functional neurol. disorder - glad that @sipsplacebo.bsky.social is picking this up!

SIPS snippet #1: Ulrike Bingel from our @sfb-trr-289.bsky.social talking in the first plenary session of the SIPS conference in beautiful Krakow, presenting our work - no effect of dopamine pharmacomodulation on experimental placebo hypoalgesia. #SIPSplacebo2025

Great input from a great webinar! Many implications for funct. sens. and motor symptoms. Sensory processing relies on feedforward modeling of sensory consequences of own actions. Many things could go wrong here & produce prediction errors as basis for aberrant sensations or invol. movements.

Today is #FND awareness day! I was lucky to learn a lot from people with FND and leading scientists within the last six months here at @kingsioppn.bsky.social. If you don't know about FND - here's a great read!

Great brand new metaanalysis on experimental nocebo effects and what factors modulate them - By @madelinestein.bsky.social in the lab of @devinterhune.bsky.social. @sfb-trr-289.bsky.social @laurenatlas.bsky.social @winstontan.bsky.social @christianbuchel.bsky.social @bencolagiuri.bsky.social

🧠 Help Us Understand Pain Perception in FND! 🧠 Looking for volunteers with & without #FND for a study in London @kingsioppn.bsky.social. Single lab visit testing pain perception with electrical stimulation. Interested? Please message me: Livia.Asan@kcl.ac.uk ✉️ Thanks for sharing!