Assistant Professor of Ophthalmic Sciences @Columbia University, Developmental ocular biology, Mom-scientist, Chai lover, All things women-in-science, Immigrant.
Feels like someone spied into my life to write this. Hits so close! 😭
Science Magazine"You feel stretched to the point of breaking. The waves of emotions are rolling over you. I am here, your future self, to tell you that you are enough. You don’t break. You put one foot in front of the other, and you not only make it through, but you have fun." https://scim.ag/3SWodeP
Congratulations to @mfsd2a.bsky.social and co-authors for this fantastic paper showing elevations in intraocular pressure compromises the blood-retina barrier. Incredible work and opens up a whole new investigative line for glaucoma! www.nature.com/articles/s41...
Intraocular pressure induced blood retinal barrier compromise in mouse models and human glaucoma - Nature CommunicationsGlaucoma is a common cause of vision loss. Here the authors show that elevated intraocular pressure disrupts the blood retinal barrier (BRB) and contributes to retinal ganglion cell death in mouse gla...www.nature.comOur recent paper picked up by The Ophthalmologist! www.theophthalmologist.com/issues/2026/...
Targeting Trabecular Meshwork MetabolismStudy suggests potential new vitamin B3 treatment for glaucoma protectionwww.theophthalmologist.comThis Diwali I am hoping that the good truly does triumph over all evil, and soon. Happy Diwali to those celebrating!
a greeting card for happy diwali with fireworks and candlesALT: a greeting card for happy diwali with fireworks and candlesmedia.tenor.comExcited to share this study! We created a developmental atlas of the anterior segment of the eye and provide crucial molecular information that guides the development of Schlemm’s canal and trabecular meshwork cell subtypes. www.biorxiv.org/content/10.1...
Single-Cell Characterization of Anterior Segment Development: Cell Types, Pathways, and Signals Driving Formation of the Trabecular Meshwork and Schlemm's CanalMorphogenesis of the anterior segment (AS) is crucial for healthy ocular physiology and vision but is only partially understood. The Schlemm's canal (SC) and trabecular meshwork (TM) are essential dra...www.biorxiv.orgPaper alert! With co-first authors Nick Tolman and @taiboli.bsky.social , we profile trabecular meshwork cells using single-cell RNA + ATAC seq, identify mitochondrial dysfunction in an early-onset glaucoma model, and use Vitamin B3 to protect against nerve damage. elifesciences.org/reviewed-pre...
Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatmentelifesciences.orgSpotted Valerie Wallace in this. Need to bring her here to bluesky. Or maybe we move to Canada? @blockintheback.bsky.social @michelcayouette.bsky.social @flyeyelab.bsky.social
University Health NetworkToday UHN launches the Canada Leads 100 Challenge! 🇨🇦💯 We’re making an ambitious investment to recruit 100 world-leading scientists. Together, we'll drive the future of health research and position Canada as a leader in global innovation! Learn more: www.uhn.ca/corporate/Ab...
My lab studies mechanisms of pediatric glaucoma and the development of tissues affected (Schlemm's canal and trabecular meshwork). I am getting creative with fundraising because, well... So if you know someone who might be interested in funding our work: joinus.cuimc.columbia.edu/index.cfm?fu...
I'm supporting Your Columbia!Your Columbia is your opportunity to be a part of the unparalleled research, education, and clinical care that takes place every day at Columbia University Irving Medical Center. It’s a potent and imp...joinus.cuimc.columbia.edu