Researcher at UCLA. PhD. Immunology, HIV. I love science, music, books and friends. Hate lies, authoritarianism and bad people. I block trolls: no debate, no comment.
Atlas of lysosomal aging reveals a metabolite signature shared with lysosomal storage disorders | Science www.science.org/doi/10.1126/... 🧪
Atlas of lysosomal aging reveals a metabolite signature shared with lysosomal storage disordersLysosomal dysfunction is a well-recognized feature of aging. Here, we used a suite of tools for rapid lysosomal isolation to construct a multitissue atlas of the metabolite changes lysosomes undergo d...www.science.orgAncient DNA confirms historical accounts of how smallpox got to the Americas | Science | AAAS www.science.org/content/arti... 🧪
Ancient DNA confirms historical accounts of how smallpox got to the Americas“Landmark” paper finds disease originated with European contactwww.science.orgHigh-speed orcas are blowing sunfish to smithereens | Science | AAAS www.science.org/content/arti... 🧪
High-speed orcas are blowing sunfish to smithereensNever-before-seen behavior may represent the giant cetaceans playing with their food, ecologists saywww.science.orgEXCLUSIVE: Congo’s Ebola epidemic started at least 4 months before it was detected | Science | AAAS www.science.org/content/arti... 🧪
EXCLUSIVE: Congo’s Ebola epidemic started at least 4 months before it was detectedA remote mining town gripped by fear saw hundreds of suspected cases before the government declared an outbreak, report sayswww.science.orgTime to HIV rebound after infusion of long-acting broadly neutralising antibodies 3BNC117-LS and 10-1074-LS and analytical treatment interruption (the RIO trial): a double-blind, randomised, placebo-controlled trial - The Lancet HIV www.thelancet.com/journals/lan... 🧪
Time to HIV rebound after infusion of long-acting broadly neutralising antibodies 3BNC117-LS and 10-1074-LS and analytical treatment interruption (the RIO trial): a double-blind, randomised, placebo-c...Long-acting bNAbs can sustain extended ART-free viral control in people treated during
early-stage HIV and represent a promising step towards achieving ART-free HIV remission.www.thelancet.comOdd shapes hidden in dense Amazon rainforest reveal sprawling ancient civilization | Science | AAAS www.science.org/content/arti... 🧪
Odd shapes hidden in dense Amazon rainforest reveal sprawling ancient civilizationNewly found earthworks suggest about 3 million people might have lived in just about 3% of the forest’s entire areawww.science.orgWhy is tracing the source of cyclosporiasis outbreaks so difficult? | Science | AAAS www.science.org/content/arti... 🧪
Why is tracing the source of cyclosporiasis outbreaks so difficult?Parasite’s biology, combined with logistical issues and budget cuts, make tracking it a major challengewww.science.orgNew U.S. rules on risky pathogen research draw mixed reviews | Science | AAAS www.science.org/content/arti... 🧪
New U.S. rules on risky pathogen research draw mixed reviewsVague language and extensive reviews could impede potentially useful research, some scientists fearwww.science.orgUnder fire from Republican senators, Fauci takes the Fifth at COVID-19 hearing | Science | AAAS www.science.org/content/arti... 🧪
Under fire from Republican senators, Fauci takes the Fifth at COVID-19 hearingFormer top NIH official says Senator Rand Paul is trying to imprison him because of an “unhinged obsession”www.science.orgwww.nature.com/articles/s41... 🧪
mRNA-based influenza vaccine expands the B cell response breadth in humans - Nature ImmunologyThis study compares the humoral response of individuals who received inactivated influenza vaccines to that of individuals who received an mRNA-based quadrivalent influenza vaccine. The mRNA-based vac...www.nature.comMetabolic traits in obesity and normal BMI in industrialised countries: a multi-country analysis of national population-based studies - The Lancet www.thelancet.com/journals/lan... 🧪
Metabolic traits in obesity and normal BMI in industrialised countries: a multi-country analysis of national population-based studiesIn industrialised countries, blood pressure and non-HDL cholesterol in older adults
with obesity are increasingly similar to those with normal BMI, with higher use of
antihypertensive and lipid-loweri...www.thelancet.comGene may help lizards get a grip in hurricane-force winds | Science | AAAS www.science.org/content/arti... 🧪
Gene may help lizards get a grip in hurricane-force winds“Huge” new study of Caribbean anole populations catches evolution in real timewww.science.orgTrump adviser’s Golden Age report on U.S. science is a missed opportunity, critics say | Science | AAAS www.science.org/content/arti... 🧪
Trump adviser’s Golden Age report on U.S. science is a missed opportunity, critics sayWhite House report aims to shake up a “calcified system,” but researchers warn it could do more harm than goodwww.science.orgActivists and leaders at global HIV meeting decry price of prevention drug | Science | AAAS www.science.org/content/arti... 🧪
Activists and leaders at global HIV meeting decry price of prevention drugGilead is criticized for lack of affordable access to lenacapavir in Latin Americawww.science.orgFossil skull flattening suggests ancient origins of infant helplessness | Science | AAAS www.science.org/content/arti... 🧪
Fossil skull flattening suggests ancient origins of infant helplessnessHomo erectus and H. floresiensis skulls both show defects similar to those modern human babies can develop after repeatedly resting on the same sidewww.science.orgThe gut microbiome of a Northern Plains tribe is in transition between global Indigenous and industrialized populations: Cell Reports www.cell.com/cell-reports... 🧪
The gut microbiome of a Northern Plains tribe is in transition between global Indigenous and industrialized populationsCrouch et al. compared the gut microbiota of healthy adults from a Northern Plains
tribe (NPT) to other global populations that practice traditional, agrarian, or industrial
lifestyles. The NPT microb...www.cell.comRemodeling of the immune-metabolic landscape triggered by long-term high-altitude exposure: Cell Reports www.cell.com/cell-reports... 🧪
Remodeling of the immune-metabolic landscape triggered by long-term high-altitude exposureWang et al. use multi-omics to map human adaptation to long-term high-altitude exposure.
Chronic hypoxia triggers a distinct strategy of innate immune activation and adaptive
suppression. Metabolicall...www.cell.comAntimalarial cytoskeletal targeting with broad apicomplexan activity | PNAS www.pnas.org/doi/10.1073/... 🧪
PNASProceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...www.pnas.orgPublic responses to atrocities depend on partisanship and context, not legal labels | PNAS www.pnas.org/doi/10.1073/... 🧪
PNASProceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...www.pnas.org