Plant genetics and epigenetics @ University of Cambridge, Department of Plant Sciences
CRISPR-mediated centromere fission generates neochromosomes with distorted meiotic inheritance in Arabidopsis biorxiv.org/content/10.6... new preprint from us - includes changing the Arabidopsis karyotype from 5 -> 6 chromosomes using Cas9 & outcomes of 5/6 chromosome hybrid meiosis
Testing Weismann’s germ plasm theory in Arabidopsis www.cell.com/current-biol... super nice lineage tracing work - do plants have a germline? @currentbiology.bsky.social
www.cell.comInteresting study suggesting that nucleus, cytoskeleton, and endomembranes preceded acquisition of mitochondria, during eukaryogenesis www.nature.com/articles/s41...
Dated gene duplications elucidate the evolutionary assembly of eukaryotes - NatureAnalysis of eukaryotic gene sequences using a relaxed molecular clock methodology indicate that eukaryotes emerged 3.0–2.25 billion years ago as a result of mitochondrial endosymbiosis with complex ar...www.nature.comRapid compensatory evolution within a multiprotein complex preserves telomere integrity www.science.org/doi/10.1126/... @levine-lab.bsky.social very cool work
Rapid compensatory evolution within a multiprotein complex preserves telomere integrityIntragenomic conflict with selfish genetic elements spurs adaptive changes in subunits of essential multiprotein complexes. Whether and how these adaptive changes disrupt interactions within such comp...www.science.orgGenetics Society Anniversary Day 25-26th June, Edinburgh genetics.org.uk/events/anniv... Society Prize Winners: Hilary Martin, Joe Felsenstein, Richard Durbin, Zam Iqbal Honorary Members: Brian Charlesworth, Deborah Charlesworth, Kay Davies, Paul Nurse, David Sherratt, Veronica van Heyningen
Anniversary Day 2026 | Genetics SocietyWe will celebrate the Genetics Society Anniversary Day in Edinburgh, June 25th-26th, 2026. The event will celebrate with talks from our Honorary Members, 2026 Prize and Medal winners, and Summer Stud...genetics.org.ukChromosome Dynamics 2026 @ Awaji Japan www.fbs.osaka-u.ac.jp/labs/fukagaw...
CRISPR-Cas–mediated heritable chromosome fusions in Arabidopsis | Science www.science.org/doi/10.1126/... Very nice work from Holger Puchta & colleagues
CRISPR-Cas–mediated heritable chromosome fusions in ArabidopsisThe genome of Arabidopsis thaliana consists of 10 chromosomes. By inducing CRISPR-Cas–mediated breaks at subcentromeric and subtelomeric sequences, we fused entire chromosome arms, obtaining two eight...www.science.orgFastGA -> ALNview; step into the centromeric matrix! github.com/thegenemyers Probably the best dot plot software on the planet...
