Associate Professor of Genetics Harvard Medical School, Boston Children's Hospital It should be fun, or what's the point? http://heimanlab.com
Endoplasmic reticulum patterns insect cuticle nanostructure. From Sachi Inagaki, Shigeo Hayashi @riken-bdr.bsky.social and colleagues: rupress.org/jcb/article/... 📕 Part of "Collective Behaviors and Self-Organization in Cells" rupress.org/jcb/collecti...
I am excited to open my lab at @ibioillinois.bsky.social in Spring 2027! We will use zebrafish & other fishy friends to reveal the genetic basis of large scale changes in the vertebrate body plan, and how this impacts both human health and evolution. Join me at UIUC! 🧬🧫🔬 www.hawkinslaboratory.com
Can Alphafold help predict protein-protein interactions in the #aECM? Our initial results seem promising! www.biorxiv.org/content/10.6...
A Lipocalin and a Hedgehog-related protein are partners in the C. elegans pre-cuticle apical extracellular matrixApical extracellular matrices (aECMs) line exposed body surfaces to shape tissues and protect them from the environment. These aECMs often organize into complex patterns and structures, but how such m...www.biorxiv.org
Excited to share our review article on cilia disassembly, published in @jcellsci.bsky.social. journals.biologists.com/jcs/article/.... We highlight how disassembly of cilia occurs, ...
Primary cilium disassembly – from mechanisms to roles in physiology and diseaseSummary: This Review explains how recent advances have expanded our models of how, when and where primary cilia disassemble and discusses emerging roles of altered disassembly in disease.journals.biologists.com
Thi Nguyen's paper on ciliary PKA activity is now published at @plosbiology.org: journals.plos.org/plosbiology/... She developed a ciliary PKA activity sensor, then, inspired by recent work from @benmyerslab.bsky.social and Susan Taylor's labs, showed that SMO inhibits PKA within cilia. 1/6
Smoothened and ciliary GPCRs regulate ciliary protein kinase A activity involved in Hedgehog signal transductionHedgehog signaling in vertebrates is transduced by the transmembrane protein Smoothened (SMO) on the primary cilium, but the underlying mechanisms remain unclear. This study shows that SMO and ciliary...journals.plos.orgImportant new work from Chia-Hsiang Chang, @nachury.bsky.social and colleagues identifying the composition of neuronal cilia in an unbiased way. Lots of surprises herein: www.science.org/doi/10.1126/...
In situ proteomics unveils specialized domains for extrasynaptic signaling on neuronal ciliaIn situ proteomics and expansion microscopy reveal nanoscale organization of postsynaptic proteins on neuronal cilia.www.science.org
Neuron-intrinsic and glial pathways regulate sensory cilia regeneration in adult C. elegans https://www.biorxiv.org/content/10.64898/2026.05.15.725580v1
🐈Amid finals and in advance of graduation, two of our most prestigious 'Purr-fessors,' Kinje and Torbie, held office hours at a cat cafe today, arranged the lab of Professor Myriam Heiman. Attendees also enjoyed boba, macarons and cat crafts. Thanks to MIT's School of Science!
Hi folks! @bu-biology.bsky.social is hiring two (!!) lecturers in Cell and Molecular Biology. It is a sweet gig in an awesome department. Come join us! academicjobsonline.org/ajo/jobs/32034
Boston University, Department of Biology Job #AJO32034, Lecturer, Department of Biology, Boston University, Boston, Massachusetts, USacademicjobsonline.org