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Профиль

Filipe Carvalho

Профиль Vively

Postdoc @ EpiMiC lab (UMR1319 Micalis, INRAE, Jouy-en-Josas 🇨🇵). Previously @ Cossart lab (Institut Pasteur, Paris 🇨🇵), @ Cabanes lab (i3S, Porto 🇵🇹). Molecular microbiology, host-pathogen interactions, bacterial dormancy and environmental persistence

www.nature.com/articles/s41...

Efficient mitochondrial A-to-G base editors for the generation of mitochondrial disease models - Nature BiotechnologyEfficient adenine base editors for mitochondrial DNA are achieved with evolved TadA deaminases.www.nature.com
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www.nature.com/articles/s41...

Programmable RNA acetylation with CRISPR–Cas13 - Nature Chemical BiologyYu et al. developed a programmable RNA acetylation system using dCas13–eNAT10 to specifically install N4-acetylcytidine on target RNAs in cells and in vivo, enabling functional studies of RNA acetylat...www.nature.com
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#MicroSky #AMR

Communications Biology

Discovery of a bicyclic peptide inhibitor of cell wall biosynthesis in the Enterobacterales demonstrates applicability of a modified phage display platform to antibiotic discovery and development. www.nature.com/articles/s42...

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#MicroSky

Lauren Bird

Excited to share this story from my PhD, out today in Nature Communications! We show that Coxiella removes cathepsin B to reduce lysosomal hostility and promote bacterial success. This depends on a vacuole established by effector CvpB. www.nature.com/articles/s41...

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Happy Freedom Day and 51st anniversary of the Carnation Revolution! 🇵🇹

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#MicroSky

bioRxiv Microbiology

Simultaneous measurements of translation rate and transcriptome in single bacterial cells by scTR-seq uncovers linked regulation within a specialized active cell population. https://www.biorxiv.org/content/10.1101/2025.04.22.649982v1

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