Incoming SNSF Ambizione group leader at EPFL. Interested in bacteria-host interactions in health and disease. https://elisabettacacace.github.io/BHI-Lab/
Check out our work on E. coli capsules! Including a 3x extended catalog of capsule loci from >37K genomes, a scalable tool to type them in silico (kTYPr) and new associations with ecology and disease! A joint effort from @microbiomeresearch.bsky.social @mucosalimmunology.bsky.social at @ethz.ch.
Nature MicrobiologyOut Now! In silico typing maps the natural diversity of Escherichia coli transporter-dependent capsules #MicroSky
Excited to announce my upcoming @snsf.ch Ambizione research group at EPFL on bacteria-host interactions, combining systems approaches and microphysiological models. 🚨 We have an open PhD position! More info on projects and how to apply here: elisabettacacace.github.io/BHI-Lab/ 🧪
How diverse are E. coli capsules? How are they linked to ecology and disease? Find out with > 25,000 genomes and MAGs including undersampled environments and hosts from all over the world. Great genomics - glycobiology synergy in Sunagawa and Slack groups at ETH! www.biorxiv.org/content/10.1... 🧪🧫🔬
The natural diversity of E. coli transporter-dependent capsulesSerotyping of bacteria using genomic information ( in silico serotyping) has increasingly replaced serology. However, the E. coli capsule serotyping system has been largely abandoned since the 1990s, ...www.biorxiv.orgLooking forward to #EESMicrobiology and excited to present our latest work on E. coli capsules on Friday! www.embl.org/about/info/c...
New approaches and concepts in microbiologywww.embl.orgCheck out this framework for de novo protein design by @mjendrusch.bsky.social and Kashif Sadiq! Happy we could contribute with our favourite phage defence system.
Michael JendruschHappy to announce the first paper from my PhD at Korbel group at @embl.org has finally been published: embopress.org/doi/full/10.1038… Collaborating with @typaslab.bsky.social, @hennig-lab.bsky.social and the EMBL PEPCF, we designed de novo inhibitors to a bacterial phage defense system 1/🧵
Our paper has been selected among Editors' Highlights for Microbiology! @natcomms.nature.com www.nature.com/collections/... 🧪🔬🧫
Microbiology and infectious diseasesThis page highlights recent articles on all aspects of bacteriology, mycology, parasitology and virology, covering the biology of pathogens, host-pathogen ...www.nature.comElisabetta CacaceDo we really know the antibiotics that we already have? Check out our story on 60y old drug nitroxoline and its new tricks! @goetheuni.bsky.social @embl.org www.nature.com/articles/s41... + great piece from the synchrotron @esrf.fr where we chased nx effects on metals www.esrf.fr/home/news/ge...
Do we really know the antibiotics that we already have? Check out our story on 60y old drug nitroxoline and its new tricks! @goetheuni.bsky.social @embl.org www.nature.com/articles/s41... + great piece from the synchrotron @esrf.fr where we chased nx effects on metals www.esrf.fr/home/news/ge...
www.nature.comInterested in antibiotic cross-resistance/sensitivity? Tired of experimental evolution? Then check our new story led by brilliant @nazgulsakenova.bsky.social, now out on Nature Microbiology @naturemicrobiol.bsky.social !
Typas LabExcited to share our study led by @SakenovaNazgul! We used chemical genetics to identify and understand cross-resistance & collateral-sensitivity (CS) between antibiotics and reduced AMR development with CS drug pairs @embl.org with @camille_goemans @EPFL_en www.nature.com/articles/s41...