We (@rileyshultz.bsky.social) tracked a recessive mutation from birth to death in honey bees. It causes ivory eyes. We collaborated across the continent to identify the mutation and it's downstream effects. Ultimately it is purified through selection on drones. We think Hamilton would be pleased!
Molecular Biology and EvolutionShultz @beeharpur.bsky.social et al. documented the trajectory of a spontaneous deleterious mutation from its origin in a single queen to its extinction, directly observing how haplodiploidy exposes recessive alleles to immediate purifying selection 🔗 doi.org/10.1093/molbev/msag156 #societyjournal