Recovery of a minor cryo-EM particle population reveals conformational equilibria linking cofactor loading, turnover, and reactivation in methionine synthase https://www.biorxiv.org/content/10.64898/2026.07.27.741092v1
Профиль
TJ McCorvie
Профиль VivelyRevealing the hidden world of shape shifting enzymes using Cryo-EM. Senior research associate at Newcastle University, UK. Currently working as part of Recon4IMD https://www.recon4imd.org Views are my own.
The consistent shooting oneself in the foot mentality for HE
Times Higher Education (THE)The Department for Education has confirmed that universities will receive £50.9 million less in teaching grants next academic year. Bridget Phillipson, the education minister has defended the reduction in light of tuition fee rises. https://ow.ly/6UWJ50ZkLlf
A tour-de-force cryo-EM study on LRRK2 regulation, which mutation of is linked to Parkinson’s disease.
cryoEM papersThe structural basis for LRRK2's activation and autoinhibition pubmed.ncbi.nlm.nih.gov/42282830/ #cryoEM