High-throughput screening approach identifies substrate-selective Hsp104 variants that counter amyloid seeding with diminished off-target effects www.cell.com/molecular-ce...

High-throughput screening approach identifies substrate-selective Hsp104 variants that counter amyloid seeding with diminished off-target effectsRyan et al. have developed a high-throughput approach for identifying variants of the amyloid disaggregase Hsp104. Their approach facilitates analysis of large Hsp104 variant libraries in parallel and...www.cell.com